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- 저자 : 조석구(Suk Ku Cho) (검색결과 2 건)
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Coagulase 음성 포도상구균에 의한 원내감염 균혈증의 임상적 고찰
이봉수(Bong Soo Lee),김태룡(Tae Ryong Kim),유석환(Suk Whan Yoo),이경혜(Gyeong Hye Lee),이여민(Yeo Min Lee),임규택(Gyu Taek Lim),조석구(Suk Ku Cho),신완식(Wan Shik Shin),강문원(Moon Won Kang) 대한내과학회 1991 대한내과학회지 Vol.40 No.2
N/A During a 3 year period from July 1986 to June 1989, 1, 230 of 11,238 cases had positive blood culture, and coagulase-negative staphylococcus (CNS) was present in 370 cases (30.1%) at St. Mary`s hospital. In a retrospective study 345 cases were examined, 125 (36.2%) were true CNS bacteremia, and 75 of 125 cases (60% of CNS bacteremia) were nosocomial in origin (defined as those in which the first positive blood culture was obtained 48 hr after admission). There was a significant annual increase in nosocomial bacteremia and little relation in age-related incidences. The most common undelying diseases were hematologic or neoplastic diseases, mainly acute leukemia, followed by gastrointestinal or liver diseases. The common medical procedures frequently related to bacteremia were cytotoxic chemotherapy, catheterization, and steroid. The most frequent clinical features were fever and leukocytosis. The main sources of bacteremia were the respiratory tract, infected wounds, injured mucosa, and catheter; however the sources were unknown in over half of the cases. The overall mortality was 25.3%, and mortality was especially high in adults over 50 years of age. Mortality due to sepsis was similar to mortality from aggravating underlying diseases, and most of the expired patients had fatal underlying diseases. In antimicrobial susceptibility, the prominent feature was resistance to many commonly used antimicrobial agents. However there was no resistance to vancomycin.
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암환자의 통증 치료에 대한 펜타닐 - TTS 의 유효성과 안정성
김훈교(Hoon Kyo Kim),이경식(Kyung Shik Lee),홍영선(Young Seon Hong),이복근(Bok Keun Lee),송치원(Chi Won Song),박진노(Jin No Park),조석구(Suk Ku Cho),김재유(Jae Yoo Kim) 대한내과학회 1999 대한내과학회지 Vol.57 No.3
N/A The transdermal administration of narcotics is one of the alternative ways of providing adequate pain relief for the patients with chronic cancer pain. A Phase 4 trial was conducted to evaluate the efficacy and safety of Fentanyl-TTS in adult patients with cancer-related pain in Korea. Methods : Patients with histologically confirmed malignancy, who have pain related to the cancer and/or therapy, pain necessitating the use of opoid analgesics, age of 18 yr or older, ability to communicate effectively with study personnel, and signed on informed consent were included. The patients were titrated with a short-acting narcotic to control their cancer pain before they are converted to a fentanyl-transdermal therapeutic system(TTS). Short acting parenteral morphine and MS contin were used as rescue medications. All patients were evaluated initially and were followed up with a pain visual analogue scale(VAS), quality of life(QOL)-VAS. Patients were asked to keep the daily record for 21 days about pain VAS, QOL-VAS, amount of rescue morphine used, and side effects. Results : Twenth two patients were enrolled from January 1996 to October 1997. The dose of fentanyl-TTS required, ranged between 25 and 75 ug/hr (25 ㎍/hr in 13, 50 ㎍/hr in 4, and 75 ㎍/hr in 2). The mean dose of morphine required before the use of the fentanyl-TTS was 135.3 mg (20-285 mg/day), but it was decreased after the use of the fentanyl-TTS. Pain VAS and QOL-VAS were in adquate level during the fentanyl- TTS treatment. Patients favored continuous use of fentanyl after the study was finished. Side effect of fentanyl-TTS was minimal. Conclusion : Transdermal fentanyl seems to be a convenient and effective analgesic for the control of cancer related pain in Korean. A controlled trial comparing fentanyl-TTS to morphine needs to be followed. (Korean J Med 57:348-356, 1999)
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