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Siamese Network for Learning Robust Feature of Hippocampi
Samsuddin Ahmed,정호엽(Ho Yub Jung) 한국스마트미디어학회 2020 스마트미디어저널 Vol.9 No.3
Hippocampus is a complex brain structure embedded deep into the temporal lobe. Studies have shown that this structure gets affected by neurological and psychiatric disorders and it is a significant landmark for diagnosing neurodegenerative diseases. Hippocampus features play very significant roles in region-of-interest based analysis for disease diagnosis and prognosis. In this study, we have attempted to learn the embeddings of this important biomarker. As conventional metric learning methods for feature embedding is known to lacking in capturing semantic similarity among the data under study, we have trained deep Siamese convolutional neural network for learning metric of the hippocampus. We have exploited Gwangju Alzheimer’s and Related Dementia cohort data set in our study. The input to the network was pairs of three-view patches (TVPs) of size 32 × 32× 3. The positive samples were taken from the vicinity of a specified landmark for the hippocampus and negative samples were taken from random locations of the brain excluding hippocampi regions. We have achieved 98.72% accuracy in verifying hippocampus TVPs.
Abol Basher,Samsuddin Ahmed,정호엽 (사)한국스마트미디어학회 2020 스마트미디어저널 Vol.9 No.2
The hippocampal volume atrophy is known to be linked with neuro-degenerative disorders and it is also one of the most important early biomarkers for Alzheimer's disease detection. The measurements of hippocampal pure volumes from Magnetic Resonance Imaging (MRI) is a crucial task and state-of-the-art methods require a large amount of time. In addition, the structural brain development is investigated using MRI data, where brain morphometry (e.g. cortical thickness, volume, surface area etc.) study is one of the significant parts of the analysis. In this study, we have proposed a patch-based ensemble model of 3-D convolutional neural network (CNN) to measure the hippocampal pure volume from MRI data. The 3-D patches were extracted from the volumetric MRI scans to train the proposed 3-D CNN models. The trained models are used to construct the ensemble 3-D CNN model and the aggregated model predicts the pure volume in one-step in the test phase. Our approach takes only 5 seconds to estimate the volumes from an MRI scan. The average errors for the proposed ensemble 3-D CNN model are 11.7±8.8 (error%±STD) and 12.5±12.8 (error%±STD) for the left and right hippocampi of 65 test MRI scans, respectively. The quantitative study on the predicted volumes over the ground truth volumes shows that the proposed approach can be used as a proxy
랜덤 포레스트를 이용한 X-선 혈관조영영상에서의 혈관 자동 영역화 알고리즘
정성희,이수찬,심학준,정호엽,허용석,장혁재,Jung, Sunghee,Lee, Soochahn,Shim, Hackjoon,Jung, Ho Yub,Heo, Yong Seok,Chang, Hyuk-Jae 대한의용생체공학회 2015 의공학회지 Vol.36 No.4
The purpose of this study is to develop an automatic algorithm for vessel segmentation in X-Ray angiogram using Random Forest (RF). The proposed algorithm is composed of the following steps: First, the multiscale hessian-based filtering is performed in order to enhance the vessel structure. Second, eigenvalues and eigenvectors of hessian matrix are used to learn the RF classifier as feature vectors. Finally, we can get the result through the trained RF. We evaluated the similarity between the result of proposed algorithm and the manual segmentation using 349 frames, and compared with the results of the following two methods: Frangi et al. and Krissian et al. According to the experimental results, the proposed algorithm showed high similarity compared to other two methods.