돈사의 상대습도가 돼지흉막폐렴의 병인에 미치는 영향

정현규,한정희,김재훈,Jeong, Hyun-kyu,Han, Jeong-hee,Kim, Jae-hoon 대한수의학회 1996 大韓獸醫學會誌 Vol.36 No.1

The effect of relative humidity in swine house on swin pleuropneumonia was examined in piglets experimentally infected with Actinobacillus pleuropneumoniae serotype 5. A total of 20 piglet were grown under 30~40%, 41~50%, 51~64% and 65~80% relative humidity chambers after intratracheal inoculation of A pleuropneumoniae. Characteristic fibrinous pleuropneumonia was observed in the pigs grown at the low relative humidity groups. The detailed results were as follows : 1. Growth performance and environment conditions were lower than high relative humidity groups. 2. Characteristic histopathological findings were fibrinous pleuritis and pneumonia accompanied congestion, hemorrhage, thrombosis and edematous change. 3. Antigenic distribution of inoculated bacterium was found mainly in alveolar macrophages or accumulated foci of macrophages adjacent to necrotic area. 4. Characteristic electron microscopic findings were proliferation of type II pneumocyte with increased lamella bodies and activated alveolar macrophages with pseudopods and widening of interstitium.

돼지생식기호흡기증후군 바이러스가 흉막폐렴에 미치는 영향 -혈청학적 및 백혈구아군 분포율에 관한 연구-

정현규 ( Hyun Kyu Jeong ),박용호 ( Yong Ho Park ),한정희 ( Jeong Hee Han ) 한국가축위생학회 2007 韓國家畜衛生學會誌 Vol.30 No.1

The purpose of this study was to evaluate the effect of a subsequent infection of porcine reproductive and respiratory syndrome(PRRS) virus to pigs with A pleuropneumonia. Twenty three 7-week-old commercial pigs were infected intratracheally with PRRS virus and/or A pleuropneumoniae serotype 5 . Serum antibody titers were examined by an enzyme-linked immunosorbent assay(ELISA) and proportion of porcine leukocyte subpopulations in peripheral blood was examined by flow cytometry. In this experiment, antibodies against PRRS virus and A pleuropneumoniae were detected at 2 weeks and 1 week postinfection and the number of antibody positive pigs were gradually increased. And in proportion to leukocyte subpopulations in peripheral blood of pigs infected with A pleuropneumoniae compared with pigs administrated with saline, the proportion of PoCD4 and N cells were increased(P<0.1). Furtherrmore, in proportion to leukocyte subpopulations in peripheral blood of pigs infected with PRRS virus followed by A pleuropneumoniae compared with pigs administrated with saline, the proportion of MHC class II, PoCD4 and B cells were significantly increased(P<0.1) The results indicated that dual infection with PRRS virus and A pleuropneumoniae induced the stronger immune responses associated with macrophages and Th cells in pigs than single infection with PRRS virus or A pleuropneumoniae.

돼지생식기호흡기증후군과 돼지 흉막폐렴의 복합감염에 따른 병리학적 연구

정현규 ( Hyun Kyu Jeong ),한정희 ( Jeong Hee Han ) 한국수의병리학회 2003 한국수의병리학회지 Vol.7 No.1

Path Morphology 개념을 이용한 MIMO 채널 모델링

정원정(Won-Jeong Jeong),유지호(Ji-Ho Yoo),김태홍(Tae-Hong Kim),김명돈(Myung-Don Kim),정현규(Hyun Kyu Chung),배석희(Seok-Hee Bae),백정기(Jeong-Ki Pack) 한국전자파학회 2010 한국전자파학회논문지 Vol.21 No.2

차세대 이동 통신 시스템에서는 높은 주파수 대역, 광대역, 다중 안테나(MIMO antenna)의 사용이 예상된다. 또한 무선 통신의 급격한 수요와 이동 통신 서비스의 폭발적인 증가로 인해 차세대 이동 통신 시스템의 최적화를 위한 검증 모델 개발 연구가 필요하다. 기존 MIMO 채널 모델의 경우 도심, 부도심, 시골, 개활지 등으로 포괄적으로 전파 환경을 분류하여 연구를 수행하였으나, 이러한 접근 방법은 예를 들어 도심 환경 내에서도 다양한 morphology가 존재할 수 있기 때문에 모델링 정확도 측면에서 취약성을 가질 수 있다. 본 논문에서는 path morphology 개념을 도입하여 전파 환경을 송?수신기 사이의 건물의 높이, 밀집도 등을 고려하여 세부적으로 분류하는 방법을 제안하였다. 광선 추적(ray tracing) 기법을 이용하여 각 환경별 delay spread(DS), AoD와 AoA의 angular spread(AS)를 분석하고, 이를 바탕으로 국내 환경에 적합한 MIMO 채널 모델을 제시하였다. The use of high frequency band, broad band and MIMO antenna is expected in the next generation mobile communication system. By the rapid increase of demand for wireless communications and the explosive increase of the mobile communication services, researches for optimization of next-generation mobile communication system are required. In the existing MIMO channel models, propagation-environments are commonly classified into urban, suburban, rural area, etc. However such approaches can have drawbacks in that many different morphologies may exist even in the urban area, for example. In this paper, we introduced path morphology concept, and proposed the method of morphology classification considering the building height, density, etc. Delay spread(DS), angular spread(AS) of AoD and AoA analyzed for each environment using the ray tracing technique. Based on the analysis, a MIMO channel model appropriate in domestic environment was suggested.

산화막 피복 원전 연료봉에서 $A_1$ 원주파의 전파 특성 해석과 실험적 검증

주영상,이정권,정현규,정용무,Joo, Young-Sang,Ih, Jeong-Guon,Jung, Hyun-Kyu,Cheong, Yong-Moo 한국비파괴검사학회 1999 한국비파괴검사학회지 Vol.19 No.3

산화막이 피복된 원전 연료봉의 원통형 쉘에 대한 공명산란 해석을 수행하고 원주파 전파 특성을 연구하였다. 피복 쉘에 대한 산란 음압의 정규 모우드 해를 구하였고 최근에 새롭게 제안된 고유 배경음압 계수를 이용하여 피복 쉘의 순수 공명 신호를 분리하였다. 12%의 상대 두께를 갖는 원통형 피복 쉘에 대하여 산화막 두께 증가에 따른 공명 원주파의 전파 특성을 해석하였다. 산화막의 존재와 그 두께가 증가할 때 정규 모우드의 차수에 따라 원주파의 전파 특성이 크게 변화한다. 제 1차 반대칭 ($A_1$) 원주파에서 특정 부분파의 위상속도는 산화막이 존재하고 그 두께가 증가함에도 불구하고 위상속도가 일정 한 특성을 보인다. 공명신호를 분리하고 공명 모우드를 확인하는 실험을 수행하여 $A_1$ 원주파의 전파 특성을 확인하였다. $A_1$ 원주파의 위상속도 일정 특성을 이용함으로써 산화막의 두께를 상대적으로 측정 할 수 있는 새로운 비파괴 평가방법을 제안하였다. The resonance scattering of acoustic waves from the cylindrical shells of nuclear fuel rods coated with oxide layers has been theoretically modeled and numerically analyzed for the propagation characteristics of the circumferential waves. The normal mode solutions of the scattering pressure of the coated shells have been obtained. The pure resonance components have been isolated using the newly proposed inherent background coefficients. The propagation characteristics of resonant circumferential waves for the shells coated with oxide layers are affected by the presence and the thickness of an oxide layer. The characteristics have been experimentally confirmed through the method of isolation and identification of resonances. The change of the phase velocity of the $A_1$ circumferential wave mode for the coated shell is negligible at the specified partial waves in spite of the presence of the oxide layer and the increase in coating thickness. Utilizing the invariability characteristics of the phase velocity of the $A_1$ mode, the oxide layer thickness of the coated shells can be estimated. A new nondestructive technique for the relative measurement of the coating thickness of coated shells has been proposed.

계절에 따른 출하돈에서의 폐렴관찰

이석규,한정희,정현규,Lee, Seok-kyu,Han, Jeong-hee,Jeong, Hyun-kyu 대한수의학회 1999 大韓獸醫學會誌 Vol.39 No.1

From 2,373 slaughtered pigs examined, 1,899 of them had visible evidence of pulmonary lesion. The lungs with pulmonary lesion were examined by grossly, histopathological technique to investigate the prevalence according to season, severity of pulmonary lesion, types of the pneumonia and relationship between rearing management and prevalence of pulmonary lesion. The results were as follows : 1. Prevalence of pneumonia according to season was 72.3% to 85.9% and the highest prevalence was in winter. 2. In the severity of pulmonary lesion, rates mild, moderate and severe lesions were 38.3%, 47.0% and 14.7%, respectively. Prevalence of mild lesion was the highest in autumn. Prevalence of moderate and severe lesions was the highest in winter. 3. In the type of pneumonia, rates of interstitial pneumonia and bronchopneumonia fibrinous pneumonia were 23.6%, 13.0%, and 3.4%, respectively. Prevalence of interstitial pneumonia was high in spring and autumn while that of broncho-pneumonia and fibrinous pneumonia was high in winter and summer, respectively. 4. In relationship of pulmonary lesions according to severity of pulmonary lesion and types of pneumonia, similarity was observed in prevalence of mild lesion and bronchopneumonia.

돼지 유행성 설사 바이러스 국내분리주의 유전학적 특성 규명

지영철,권혁무,정현규,한정희,Chi, Yong-zhe,Kwon, Hyuk-moo,Jeong, Hyun-kyu,Han, Jeong-hee 대한수의학회 2003 大韓獸醫學會誌 Vol.43 No.2

Porcine epidemic diarrhea virus(PED), a member of Coronaviridea, is the etiological agent of enteropathogenic diarrhea in swine. The purpose of this study was to investigate genetic characteristic of PEDV isolated in Korea. Nucleocapsid(N) gene and membrane (M) gene of recent Korean PEDV strains isolated in 2001 were amplified, cloned, sequenced and analyzed. N gene of seven Korean PEDV field isolates bad 94.5% to 99.4% nucleotide and 92.4% to 99.4% amino acid sequence homology each other. Nucleotide and amino acid sequences of Korean field PEDVs were different from published foreign PEDVs, showing 95.1% to 98.0% nucleotide and 93.5% to 97.6% amino acid sequence homology. By phylogenetic tree analysis on based nucleotide sequences, PEDVs were clustered into four groups. By phylogenetic tree analysis based on amino acid sequences. PEDVs were clustered into five groups. M gene of our Korean PEDV field isolates had 99.6% to 100% nucleotide and 98.7% to 100% amino acid sequence homology each other. Nuclotide and amino acid sequences of Korean field PEDVs were different from published foreign PEDVs, showing 98.5% to 98.8% nucleotide and 97.3% to 97.8% amino acid sequence homology. By phylogenetic tree analysis based on nucleotide and amino acid sequences, PEDVs were clustered into two groups which were Korean PEDV isolate group and foreign PEDV isolate group.

송.수신 안테나 스케줄링에 기반한 MIMO-OFDM 시스템의 HARQ 스위칭 기법

김규현,강승원,장경희,정병장,정현규,Kim, Kyoo-Hyun,Knag, Seoung-Won,Chang, Kyung-Hi,Jeong, Byung-Jang,Chung, Hyun-Kyu 한국통신학회 2007 韓國通信學會論文誌 Vol.32 No.6a

본 논문에서는 최근 많은 연구가 진행되고 있는 공간 다중화 기법인 Iterative BLAST를 기반으로 채널 값의 Sum을 이용하여 양호한 통신 링크를 적응적으로 선택하는 송/수신 안테나 선택 기법과 선택된 안테나를 사용하여 시스템의 신뢰성을 향상시키기 위한 안테나 스케줄링 기반 Hybrid-Automatic Repeat reQuest (UARO) 스위칭 기법을 결합한다. 본 논문에서 제안된 HARQ 스위칭 알고리즘은 각 안테나에 삽입된 CRC (Cyclic Redundancy Check) 코드를 사용하여 안테나별로 ACK (Acknowledgement) 와 NAK (Non Acknowledgement)를 확인한 후, 재전송 요구 시, 송신 안테나를 스케줄링하여 ACK 안테나에서는 CC (Chase Combining) 기법을, NAK 안테나에서는 IR (Incremental Redundancy) 기법을 적용하여 재전송이 이루어지게 한다. 본 논문에서 제안한 알고리즘의 적용시, SNR 이득과 공간 다이버시티 이득이 발생하여 기존 HARQ 시스템에 비하여 링크 성능이 향상됨을 SCM-E 채널 환경에서 모의 실험을 통하여 검증한다. In this paper, we combine the Hybrid-Automatic Repeat reQuest (HARQ) algorithm with joint Tx and Rx antenna selection based on the reliability of the individual antennas links. The cyclic redundancy check (CRC) is applied on the data before being encoded using the Turbo encoder. In the receiver the CRC is used to detect errors of each antenna stream and to decide whether a retransmission is required or not. The receiver feeds back the transmitter with the Tx antennas ordering and the acknowledgement of each antenna (ACK or NACK). If the number of ACK antennas is higher than the NACK antennas, then the retransmission takes place from the ACK antennas using the Chase Combining (CC). If the number of the NACK antennas is higher than the ACK antennas then the ACK antennas are used to retransmit the data streams using the CC algorithm and additional NACK antennas are used to retransmit the remaining streams using Incremental Redundancy (IR, i.e. the encoder rate is reduced). Furthermore, the HARQ is used with the I-BLAST (Iterative-BLAST) which grantees a high transmission rate.

항혈청 투여에 의한 돼지 전염성 위장염의 예방효과 II.임상검사, 병리조직학적 검사, 면역조직화학적 검사

지영철,한정희,권혁무,정현규,Chi, Yong-Zhe,Han, Jeong-Hee,Kwon, Hyuk-Moo,Jeong, Hyun-Kyu 한국수의병리학회 2003 한국수의병리학회지 Vol.7 No.1

The purpose of this study was to investigate protective effects against transmissible gastroenteritis virus (TGEV) infection in piglets by administration of the TGEV antiserum orally at 2hrs, 24hrs and 36hrs after birth. Five piglets administered with the TGEV antiserum were experimentally challenged with TGEV at four-day-old. Control group was four piglets challenged with TGEV only. Clinical signs and gross, histopathological and immunohistochemical findings were examined. In clinical signs, piglets of the control group appeared the typical signs such as severe watery diarrhea, depression and anorexia but piglets of the TGEV antiserum adminstered group recovered progressively. In clinical signs, piglets of the control group appeared the typical signs such as severe watery diarrhea, depression and anorexia but piglets of the TGEV antiserum adminstered group recovered progressively. In mortality, control group showed 75%, but TGEV antiserum adminstered group showed 20.0 %, respectively. In gross findings, piglets of the control group appeared the typical findings of congestion, distension of lumen, contaning curdes of undigested milk in stomach. But gross findings of piglets of the TGEV antiserum adminstered group appeared milder than them of control group. In histopathological findings, piglets of the control group appeared the typical findings of villous atrophy and fusion, congesion, exfoliation, vacuolation, squamation, loss of cilia and proliferation of crypt. But histopathological findings of piglets of the TGEV antiserum adminstered group appeared milder than them of control group. In immunohistochemical findings, piglets of the TGEV antiserum adminstered group showed more intensive in reaction for IgA and IgG than them of control group. The recation for IgA was stronger than that of IgG. It was concluded that oral administration of TGEV antiserum to piglets was effective to prevent TGEV infection and reduce their mortality.

돼지 유행성 설사병(porcine epidemic diarrhea)의 상재화에 대한 혈청학적 증명

박봉균,한경수,류광수,김준영,정현규,Park, Bong-kyun,Han, Kyung-soo,Lyoo, Kwang-soo,Kim, Jun-young,Jeong, Hyun-kyu 대한수의학회 1998 大韓獸醫學會誌 Vol.38 No.4

The persistence of porcine epidemic diarrhea virus(PEDV) infection was demonstrated in 7 swine farms employing continuous pig flow management even after seasonal outbreaks. Clinically, sporadic postweaning diarrhea was a major concern in those farms. Subsequently circulatory antibody detection using serum neutralizing test made useful for confirmation of PEDV persistent infections. The persistence of PEDV in the premise might have induced recurrence over the period of time.