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원발성 담즙성 견경변증과 Isolated pulmonary hypertension을 동반한 미만성 경피증(Diffuse scleroderma)
장현규 ( Hyun Kyu Chang ),정상식 ( Sang Sig Chung ),정행섭 ( Haing Sub R. Chung ),이성희 ( Sung Hee Lee ),허환 ( Hwan Herr ) 대한류마티스학회 1997 대한류마티스학회지 Vol.4 No.2
Primary biliary cirrhosis is frequently associated with a variety of disorders presumed to be autoimmune in nature, such as Sjogren`s syndrome, scleroderma, rheumatoid arthritis, systemic lupus erythematosus, and autoimmune thyroiditis. Scleroderma has been recognized in association with primary biliary cirrhosis. Most cases present as the CREST (calcinosis cutis, Raynaud`s phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia) syndrome. Isolated pulmonary hypertension develops in a small proportion of patients, nearly all of whom have limited cutaneous involvement. We report a case who has diffuse scleroderma associated with primary biliary cirrhosis and isolated pulmonary hypertension.
장현규 ( Hyun Kyu Chang ),정승문 ( Seung Mun Jung ),정행섭 ( Haing Sub R. Chung ) 대한류마티스학회 1998 대한류마티스학회지 Vol.5 No.1
The antiphospholipid syndrome is characterized by arterial thrombosis, venous thrombosis, pregnancy wastage, and thrombocytopenia associated with a persistently positive lupus anticoagulant and/or moderate to high positive anticardiolipin antibodies(IgG or IgM). The antiphospholipid antibodies have been detected in many medical conditions, but the antiphospholipid syndrome (APS) has mainly been restricted to the primary antiphospholipid syndrome and APS associated with systemic lupus erythematosus. Rarely, the APS has been reported in other autoimmune disorders in the literature. We describe a woman with a limited form of scleroderma and the APS manifested by complete occlusion of left axillary artery with probable thrombotic occlusive nature, thrombocytopenia, prolonged aPTT, and persistently positive lupus anticoagulant.
다발성 식도궤양과 회장말단부궤양을 동반한 베체트병 2예
장현규 ( Hyun Kyu Chang ),김연석 ( Yeon Suk Kim ),김완수 ( Wan Soo Kim ),정행섭 ( Haing Sub R. Chung ),정승문 ( Seung Mun Jung ) 대한류마티스학회 1999 대한류마티스학회지 Vol.6 No.3
Behcet`s disease is a chronic polysymptomatic disease of recurrent systemic vasculitis. The etiology remains unclear. This disease affects several organs of the body concurrently or consecutively and sometimes has a serious outcome, depending upon the system involved. Though gastrointestinal symptoms are relatively common in Behcet`s disease, ulcerative change of the intestine is infrequent. The most common sites for the intestinal Behcet`s disease are terminal ileum and cecum. Only a few literatures report the esophageal ulcers in Behcet`s disease. We describe 2 cases of Behcet`s disease who have multiple ulcers in esophagus and terminal ileum. Esophageal ulcers have improved with low-dose prednisolone, colchicine and sulfasalazine in these patients.
장현규 ( Hyun Kyu Chang ),허승호 ( Seung Ho Hur ),정행섭 ( Haing Sub R. Chung ) 대한류마티스학회 2000 대한류마티스학회지 Vol.7 No.1
Giant cell arteritis is an inflammatory disease that mainly involves the cranial branches of the arteries originating from the aortic arch. It affects the white populations over the age of 50 almost exclusively who live in Northern Europe and in the United states. There is close relationship between giant cell arteritis and polymyalgia rheumatica. So far, there have been a few reports of temporal arteritis in Korea. However, giant cell arteritis with typical pathological findings in temporal artery has not been reported. We describe a case who showed typical pathological findings of giant cell arteritis in superficial temporal artery. She had been diagnosed as polymyalgia rheumatica in several months ago.