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컴퓨터 단층촬영을 이용한 중안모 계측과 상악골 절단술에의 응용
정필훈,유충규,이은경,서제덕,정일혁,Choung, Pill-Hoon,Yoo, Chung-Kyu,Lee, Eun-Kyung,Suh, Je-Duck,Chung, Il-Hyuk 대한악안면성형재건외과학회 2006 Maxillofacial Plastic Reconstructive Surgery Vol.28 No.3
Various methods have been used in the past to indirectly analyze the craniofacial region. Among these, the lateral and posterior-anterior cephalometircs are used for the evaluation of the dentofacial deformities. However, cephalometircs create inaccuracies because of the inherent enlargement and distortion of the image. The interpretation of cephalometric films is also problematic: the number of anatomic landmarks that can be identified accurately is limited, and the overlap of structures on a radiograph making locating these landmarks difficult. To overcome these problems, computed tomography(CT) has been recommended as an useful modality in the diagnosis, surgical planning, and follow-up of craniofacial anomalies. There is no significant enlargement or distortion of the image, overlap of structure, or tracing error. And the number of anatomic landmarks is vast. The purpose of this study was to examine the orbit and midfacial region using Occlusal Maxillary CT, consisted of slices parallel to the occlusal plane. Based on these CT scan, we provide the data that could be applied to monitor an individual patient's skeletal pattern and the guide to the maxillary osteotomy.
정일혁,정종훈,정필훈,Chung, Il-Hyuk,Chung, Jong-Hoon,Choung, Pill-Hoon 대한구강악안면외과학회 2004 대한구강악안면외과학회지 Vol.30 No.5
Objectives : The proper development of the facial structures relies upon a sequence of tightly regulated signaling interactions between the ectoderm and mesoderm involving the participation of several families of signaling molecules. Among these, bone morphogenetic proteins (BMPs) have been suggested to be a key signal that regulates the development of the mandible and the initiation and morphogenesis of the teeth. The aim of this study was to examine the artificial development of the mandibular structures and to examine the role of BMPs on tooth morphogenesis and differentiation using an organ culture system. Materials and Methods : The tooth germs from Ed 11.5, 13.5 mice were dissected, and transplanted into the diastema of the mandible primordia. The mandibles containing the transplanted tooth germs were cultured in vitro. During this period, beads soaked with BMP4 were implanted around the transplanted tooth germs. In addition, a diastema block containing the transplanted tooth germ was dissected, then transferred to an adult mouse kidney. After the organ culture, the developing mandibular explant was removed from the kidney and prepared for the tissue specimens. Odontogeneis of the transplanted tooth germs was examined after Hematoxylin-eosin, Masson-trichrome staining. Results : Proliferation and differentiation of the tooth germs cultured in the diastema was observed. In the BMP4-treated tooth germs, the formation of the first and second molars was noted. The crown of the developing tooth showed the formation of a mature cusp with the deposition of enamel and dentin matrix. In conclusion, it was confirmed that BMP4 is involved in the formation of a dental crown and the differentiation of ameloblasts and odontoblasts of the molar tooth during the development of the transplanted tooth germs.
채윤필(Youn Pill Chae),안희용(Heui Young Ann),정필훈(Pill Hoon Choung),김창수(Chang Soo Kim),정상철(Sang Chul Chung) 대한악안면성형재건외과학회 1989 Maxillofacial Plastic Reconstructive Surgery Vol.11 No.2
사회가 다양해지고 공업화됨에 따라 안면부의 외상이 크게 증가하였으며, 그 외상 정도 또한 더욱 심화되었다. 안면골절중 가장 많은 발생빈도를 차지하는 것은 비골골절이다. 그러나, 골절된 비골에 대한 즉시 치료율은 다른 안면골에 비해 높지 않다. 또한 다른 안면골 골절, 특히 악골 골절과 동반된 경우에 있어서는 마취 기술상 동시 수술이 쉽지 않다. 따라서 많은 수의 비골골절이 즉시 치료되지 못해 변형된 형태로 남게 된다. 이러한 외상성 비변형은 심미적으로나 기능적으로 환자에게 큰 불편을 초래하므로 정비술을 요하게 된다. 코의 외상성 변형은 크게 비골부변형, 비연골부 변형, 피부변형과 다른 주위 구조물 (안와부, 전두부)과 동반된 변형으로 나눌 수 있다. 안와부 또는 전두부와 동반된 비변형에 있어서는 비안각 또는 전비각의 재건에 유의하여야 한다. 단순한 비변형에 있어서는 비연골간 절개 또는 구내절개술을 통한 재건술이 많이 이용된다. 정비술 방법으로는 비골절단술, 연골이식술, 골이식술 및 이물질매식술 등이 있다. 본원에서는 비연골간 절개를 이용한 골 및 연골이식과 이물질 매식 그리고 구내절개를 이용한 골절단술로 외상성 비변형을 이차적으로 재건한 바 만족할만한 결과를 얻었기에 이에 보고하는 바이다. The major causes of the facial bone fractures are automobile collision, industrial or other accident, and fights. Of the facial bone fractures, the nasal bone fractures are monst common. According to Schroeder et al., 50% of facial bone fractures are isolated fractures of the nasal pyramid. But the fractured nasal bone is not immediately treated as other facial bone fractures. And it is necessary to delay the treatment of the combined nasal bone fractures with other jaw bone fractures because of the difficult anesthetic techniques Therefore there are many residual nasal deformities following a fracture; nasal hump, saddle nose and alar rim defect. Many authors have suggested the methods to correct the post - traumatic nasal deformities. We heve treated several patients with several methods and this paper presents the operating methods and results.
구강내 점막과 유리피판에 사용되는 피부의 rete ridge에 관한 2차원 및 3차원적 구조 연구
안강민(Kang-Min Ahn),정헌종(Hun-Jong Chung),김윤태(Yoon-Tae Kim),팽준영(Jun-Young Paeng),신영민(Young-Min Shin),성미애(Mi-Ae Sung),박희정(Hee-Jung Park),명훈(Hoon Myoung),황순정(Soon-Jung Hwang),최진영(Jin-Young Choi),정필훈(Pill-Ho 대한구강악안면외과학회 2005 대한구강악안면외과학회지 Vol.31 No.2
Objects : With the advancement of tissue engineering techniques, the effort to develop bioartificial mucosa have been actively delivered. The problem we met with this technique is the lack of mechanical strength between kerationocyte layer and dermal layer, where in the normal skin and mucosa, they are tightly bound with rete ridge structure. The purpose of this study is to understand the 2D and 3D structure of rete ridge of mucosa and skin paddle for rendering more biomimetic structure to the artificial mucosa. Materials and Methods : Oral mucosa and skin from the patients who received the oral surgery and maxillofacial reconstruction were harvested. The epidermis was separated from the dermis after treating with dispase for 12-16 hours. H & E staining was performed for 2D(dimensional) structure study and confocal LASER and SEM study were performed for 3D structure. Mean height(Sc) and arithmetic mean deviation(Sa) of all surface height were calculated. Results : The average height of rete ridge of skin flap was between 67.14㎛ and 194.55㎛. That of oral mucosa was between 146.26㎛ and 167.51㎛. Pressure bearing area and attached gingiva of oral mucosa showed deeper rete ridges. Conclusion : To obtain the adequate strength of artificially cultured keratinocyte skin and mucosa flap, it is necessary to imitate the original skin and mucosa structure, especially rete ridge. Through this study, 2D and 3D rete ridge structure of normal mucosa and skin was obtained. These results can be used as basis for substrate morphology for keratinocytes culture.
이종호(Jong-Ho Lee),서제덕(Je-Duck Suh),이은진(Eun-Jin Lee),명훈(Hoon Myoung),황순정(Soon-Jung Hwang),최진영(Jin-Young Choi),정필훈(Pill-Hoon Chung),김명진(Myung-Jin Kim) 대한구강악안면외과학회 2002 대한구강악안면외과학회지 Vol.28 No.5
Ameloblastoma of the maxilla is an unusual epithelial tumor of odontogenic origin. According to many authors and reports, ameloblastoma account for approximately 1% of all tumors of the jaws, but when pseudotumors and cysts are excluded, the ratio rises to 11%. Of these tumors,80% originate in the mandible, while 20% originate in the maxilla. Although it is considered benign histopathologically, it can behave in a slowly growing infiltrative fashion, with multiple recurrences and eventual intracranial, or even distant, spread. We clinically analyzed common site in maxilla, radiographic findings, recurrence rate, duration between treatment and recurrence, the presence and site of distant metastasis in 15 patients who were diagnosed as ameloblastoma of the maxilla and took treatments from 1985 to 1999 in Dept. of Oral and Maxillofacial Surgery, Dental Hospital, Seoul National University. In this paper, treatment outcomes and our clinical experiences of maxillary ameloblastoma are reported with review of literatures.
이응태 ( Eung Tae Lee ),임기택 ( Ki Taek Lim ),김장호 ( Jang Ho Kim ),임애리 ( Ae Li Im ),손현목 ( Hyun Mok Son ),조종수 ( Chong Su Cho ),정필훈 ( Pill Hoon Choung ),정종훈 ( Jong Hoon Chung ) 한국조직공학·재생의학회 2008 조직공학과 재생의학 Vol.5 No.4
Low-intensity ultrasound stimulation produces significant multi-functional effects that are directly relevant to bone formation. It was previously found that low-intensity ultrasound stimulation enhanced bone regeneration although the exact cellular mechanism is not clear. The aim of the present study is to investigate the effect of low-intensity ultrasound stimulation on proliferation of alveolar bone marrow stem cells. Before low-intensity ultrasound stimulation, alveolar bone marrow stem cells were cultured for 24h to facilitate their attachment. The cells were cultured in medium with or without low-intensity ultrasound stimulation. The ultrasound frequency was 1 MHz. Cell cultures stimulated with ultrasound were conducted by three treatment groups - group 1: intensity(100, 200, 300, 400 and 500 mW/cm2), group 2: duty cycle(5, 10, 30 and 50%) and group 3: duration time(1, 3, 5, 10, 20 and 30 min). The effect of low-intensity ultrasound stimulation were evaluated by cell number and morphological changes. The proliferation rates of alveolar bone marrow stem cells for the particular stimulated groups were larger than those of control groups. After low-intensity ultrasound stimulation(intensity: 100 mW/cm2, duty cycle: 30% and duration time: 10 min), the alveolar bone marrow stem cell counts were significantly increased(p < 0.05). This study suggested that the cell growth could be enhanced by appropriate low-intensity ultrasound stimulation.
이종호(Jong-Ho Lee),안상철(Sang-Cheol Ahn),이은진(Eun-Jin Lee),서병무(Byoung-Moo Seo),최진영(Jin-Young Choi),정필훈(Pill-Hoon Chung),김명진(Myung-Jin Kim) 대한구강악안면외과학회 2002 대한구강악안면외과학회지 Vol.28 No.5
Pigmented villonodular synovitis(PVNS) usually presents as a benign proliferative monoarticular arthritis that affects the knee in 80% of cases, followed in frequency by the hip, ankle, and calcaneocuboid joint. PVNS rarely affects temporomandibular joint area. Patients typically complain of pain, locking, and recurrent swelling. Tumor progression limits the range of movement of the joint and causes it to become stiff and firm. Sometimes a palpable mass can be appreciated. Aggressive form of PVNS invades into adjacent bones and soft tissues, is confused with other types of neoplasia. Here we report 2 cases of the PVNS on a temporomadibular
CORRECTIVE RHINOPLASTY OF THE POST-TRAUMATIC RESIDUAL NASAL DEFORMITIES
Chung,Sang Chul,Ann,Heui Yong,Chae,Yun Pill,Kim,Chang Soo,Choung,Pill Hoon 大韓顎顔面成形再建外科學會 1989 Maxillofacial Plastic Reconstructive Surgery Vol.11 No.2
The major causes of the facial bone fractures are fractures are automobile collision or other accident, and fights. Of the facial bone fractures, the nasal bone fractures are monst common. According to Schroeder et ai., 50% of facial bone fractures are isolated fractures of the nasal pyramid. But the fractured nasal bone is not immediately treated as other facial bone fractures. And it is necessary to delay the treatment of the combined nasal bone fractures with other jaw bone fractures because of the difficult anesthetic techniques. Therefore there are many residual nasal deformities following a fracture; nasal hump, saddle nose and alar rim defect. Many authors have suggested the methods to correct the post-traumatic nasal deformities. We have treated several patients with several methods and this paper presents the operating methods and results.
CERVICOFACIAL FLAP IN RECONSTRUCTION OF FACIAL DEFECTS AND SCARS
Min,Byung Kook,Lee,Chung Hoon,Min,Seong Kee,Kim,Chang Soo,Choung, Pill Hoon 大韓顎顔面成形再建外科學會 1990 Maxillofacial Plastic Reconstructive Surgery Vol.12 No.1
외상에 의한 안면부의 반흔 및 안면 종양에 의한 결손은, 사회적 적응면에서 고찰할 때, 환자 자신에 대한 심리적 부담 및 타인에 대한 혐오감을 유발시킨다. 그러므로 안면부의 반흔 구축 및 결선 수복은 환자의 사회적 적응을 쉽게 유도해야 하며 방법적인 면을 고려할 때, 보다 심미적인 결과를 추구해야 한다. 일반적으로 안면 반흔의 구축 및 결손의 수복 방법에는 피부 이식 또는 피판 이식이 이용되고 있으나, 원거리 피부 의식의 결과, 안면부의 피부와 상이한 양태를 나타내고 있어 심미적이지 못하며, 안면부에서의 피판 이식은 수복할 수 있는 반흔 및 결손의 범위가 제한되어 있는 결점이 있다. 경안 피판에 의한 반흔 구축 및 결손 수복은 와반증을 동반할 수 있는 단점이 있으나, 혈류 공급이 우수하고, 봉합후 반흔이 적으며, 보다 광범위한 반흔 및 결손을 수복할 수 있고, 안면부 피부와 성상이 유사하여 보다 심미적이다. 본 교실에서는 화상에 의한 안면부 반흔과 혈관종 절제술에 의한 결손 수복에 경안 피판을 이용하여 심미적으로 우수한 결과를 얻었기에 저자등은 문헌 고찰과 함께 증례 보고를 하는 바이다.