덧눈꺼풀교정술 또는 눈꺼풀처짐교정술 후 난시의 변화

정진욱,김남주,정호경,곽상인.Jin-Wook Jeoung. M.D.. Nam-Ju Kim. M.D.. Ho-Kyung Choung. M.D... Sang-In Khwarg. M.D.. 대한안과학회 2005 대한안과학회지 Vol.46 No.9

Purpose: To analyze the changes of astigmatism and keratometric cylinder by using the scalar and vector analysis method in children who had undergone surgery for epiblepharon or ptosis. Methods: The study subjects were 142 eyes of 79 patients who had undergone surgery for epiblepharon or ptosis. We examined the cycloplegic refractive error and keratometric astigmatism by auto-refractometry before and 2 months after surgery. Astigmatic changes were analyzed through the scalar and vector analysis method. Results: The mean age of the patients was 5.27±2.18 years of age, and the male to female ratio was 35:44. There were 98 eyes of 49 patients in the epiblepharon surgery group, 28 eyes of 22 patients in the ptosis surgery group, and 16 eyes of 8 patients in the epiblepharon and ptosis surgery (combined surgery) group. The epiblepharon surgery group demonstrated a decrease in with-the-rule astigmatism, and the changes in magnitude (p<0.001) and vector (p<0.05) of keratometric cylinder were statistically significant. The ptosis surgery group demonstrated an increase in with-the-rule astigmatism and the changes in magnitude and vector of astigmatism were statistically significant (both p<0.01). The combined surgery group demonstrated an increase in with-the-rule astigmatism and the changes in vector of astigmatism and magnitude of keratometric cylinder were statistically significant (both p<0.05). Conclusions: Our results showed significant astigmatic change in eyes that underwent surgery for epiblepharon or ptosis. Therefore, careful cycloplegic refraction is necessary after epiblepharon or ptosis surgery.

군날개 수술 후 발생한 괴사성 공막염에 대한 양막이식술의 치료 효과

정진욱 ( Jin Wook Jeoung ) , 윤여민 ( Yeo Min Yoon ) , 이재림 ( Jae Lim Lee ) , 위원량 ( Won Ryang Wee ) , 이진학 ( Jin Hak Lee ) , 김미금 ( Mee Kum Kim ) 대한안과학회 2004 대한안과학회지 Vol.45 No.12

아르곤 레이저를 이용한 결막모반의 제거

정진욱 ( Jin Wook Jeoung ) , 김태임 ( Tae Im Kim ) , 이진학 ( Jin Hak Lee ) , 위원량 ( Won Ryang Wee ) , 권지원 ( Ji Won Kwon ) 대한안과학회 2004 대한안과학회지 Vol.45 No.12

군날개 수술 후 발생한 괴사성 공막염에 대한 양막이식술의 치료 효과

정진욱 ( Jin Wook Jeoung ),윤여민 ( Yeo Min Yoon ),이재림 ( Jae Lim Lee ),위원량 ( Won Ryang Wee ),이진학 ( Jin Hak Lee ),김미금 ( Mee Kum Kim ) 대한안과학회 2004 대한안과학회지 Vol.45 No.12

아르곤 레이저를 이용한 결막모반의 제거

정진욱 ( Jin Wook Jeoung ),김태임 ( Tae Im Kim ),이진학 ( Jin Hak Lee ),위원량 ( Won Ryang Wee ),권지원 ( Ji Won Kwon ) 대한안과학회 2004 대한안과학회지 Vol.45 No.12

수포각막병증에서 양막 이식술의 효용성

박정현,정진욱,위원량,이진학,김미금,이재림.Jung Hyun Park. M.D.. Jin Wook Jeoung. M.D.. Won Ryang Wee. M.D.. Ph.D... Jin Hak Lee. M.D. Ph.D... Mee Kum Kim. M.D.. Ph.D... Jae Lim Lee. M.D. 대한안과학회 2007 대한안과학회지 Vol.48 No.8

Purpose: To evaluate the efficacy of amniotic membrane (AM) transplantation in symptomatic bullous keratopathy using cryo-preserved or lyophilized AM. Methods: Eight bullous keratopathic patients, who experienced intractable pain despite medication and the application of a therapeutic lens, underwent permanent AM transplantation with 5 cryo-preserved and 3 lyophilized AMs following removal of epithelium using a trephine. The time to re-epithelization and the subsidence of pain were evaluated retrospectively. Results: Mean follow-up was 252±171.0 days. Pain relief and re-epithelization were obtained in all eight patients. The times to complete relief of pain was 32.2±22.7 days in patients with cryo-preserved AM transplantations (n=5) and 22.0±18.0 days in those with lyophilized AM transplantations (n=3) (p=0.549, Mann-Whitney U test). Respective times to re-epithelization were 25.4±20.7 days and 23.0±25.2 days (p=0.297). There were no significant differences in the diameter of transplanted AMs between the two groups (7.6±0.2 vs. 7.3±0.3 mm, p=0.172). Conclusions: Permanent AM transplantation effectively reduced the intractable pain caused by epithelial bulla. Whether the AM was cryo-preserved or lyophilized did not affect the efficacy of the treatment.

수치해석을 이용한 팬 아웃 웨이퍼 레벨 패키지의 휨 경향 및 신뢰성 연구

이미경,정진욱,옥진영,좌성훈,Lee, Mi Kyoung,Jeoung, Jin Wook,Ock, Jin Young,Choa, Sung-Hoon 한국마이크로전자및패키징학회 2014 마이크로전자 및 패키징학회지 Vol.21 No.1

최근 모바일 응용 제품에 사용되는 반도체 패키지는 고밀도, 초소형 및 다기능을 요구하고 있다. 기존의 웨이퍼 레벨 패키지(wafer level package, WLP)는 fan-in 형태로, I/O 단자가 많은 칩에 사용하기에는 한계가 있다. 따라서 팬 아웃 웨이퍼 레벨 패키지(fan-out wafer level package, FOWLP)가 새로운 기술로 부각되고 있다. FOWLP에서 가장 심각한 문제 중의 하나는 휨(warpage)의 발생으로, 이는 FOWLP의 두께가 기존 패키지에 비하여 얇고, 다이 레벨 패키지 보다 휨의 크기가 매우 크기 때문이다. 휨의 발생은 후속 공정의 수율 및 웨이퍼 핸들링에 영향을 미친다. 본 연구에서는 FOWLP의 휨의 특성과 휨에 영향을 미치는 주요 인자에 대해서 수치해석을 이용하여 분석하였다. 휨을 최소화하기 위하여 여러 종류의 epoxy mold compound (EMC) 및 캐리어 재질을 사용하였을 경우에 대해서 휨의 크기를 비교하였다. 또한 FOWLP의 주요 공정인 EMC 몰딩 후, 그리고 캐리어 분리(detachment) 공정 후의 휨의 크기를 각각 해석하였다. 해석 결과, EMC 몰딩 후에 발생한 휨에 가장 영향을 미치는 인자는 EMC의 CTE이며, EMC의 CTE를 낮추거나 Tg(유리천이온도)를 높임으로서 휨을 감소시킬 수 있다. 캐리어 재질로는 Alloy42 재질이 가장 낮은 휨을 보였으며, 따라서 가격, 산화 문제, 열전달 문제를 고려하여 볼 때 Alloy 42 혹은 SUS 재질이 캐리어로서 적합할 것으로 판단된다. For mobile application, semiconductor packages are increasingly moving toward high density, miniaturization, lighter and multi-functions. Typical wafer level packages (WLP) is fan-in design, it can not meet high I/O requirement. The fan-out wafer level packages (FOWLPs) with reconfiguration technology have recently emerged as a new WLP technology. In FOWLP, warpage is one of the most critical issues since the thickness of FOWLP is thinner than traditional IC package and warpage of WLP is much larger than the die level package. Warpage affects the throughput and yield of the next manufacturing process as well as wafer handling and fabrication processability. In this study, we investigated the characteristics of warpage and main parameters which affect the warpage deformation of FOWLP using the finite element numerical simulation. In order to minimize the warpage, the characteristics of warpage for various epoxy mold compounds (EMCs) and carrier materials are investigated, and DOE optimization is also performed. In particular, warpage after EMC molding and after carrier detachment process were analyzed respectively. The simulation results indicate that the most influential factor on warpage is CTE of EMC after molding process. EMC material of low CTE and high Tg (glass transition temperature) will reduce the warpage. For carrier material, Alloy42 shows the lowest warpage. Therefore, considering the cost, oxidation and thermal conductivity, Alloy42 or SUS304 is recommend for a carrier material.

안면화염혈관종 환자에서의 녹내장 발생양상 및 치료

김미진(Mi Jin Kim),이원준(Won June Lee),박기호(Ki Ho Park),김태우(Tae-Woo Kim),이은지(Eun Ji Lee),유영석(Young Suk Yu),정진욱(Jin Wook Jeoung) 대한안과학회 2017 대한안과학회지 Vol.58 No.11

목적: 안면화염혈관종 환자의 녹내장 발생여부 및 시기, 치료방법에 대해 알아보고자 하였다. 대상과 방법: 2000년 1월부터 2016년 8월까지 안면화염혈관종 환자 58명 116안을 대상으로 후향적으로 의무기록을 분석하였다. 환자 들의 초진 시 연령, 시신경유두함몰 비율, 각막 직경 및 안압 상승여부, 녹내장의 발생여부와 시기, 치료 방법 등을 조사하였다. 녹내장이 발생한 눈과 녹내장이 발생하지 않은 눈의 임상적 특징을 비교하였으며, 추가적으로 녹내장이 발생한 눈 중에서 수술을 받은 눈과 그렇지 않은 눈으로 나누어 그 차이를 비교하였다. 결과: 안면화염혈관종 환자 58명 116안 중에서 녹내장을 진단 받은 것은 38명 46안(39.66%)이었고, 이 중에서 녹내장 수술을 시행한 경우는 26명 27안(58.69%)이었다. 대상환자 58명 중 19명(32.76%)에서 경련, 발달지연, 정신지체, 편마비 등의 신경학적 증상을 동반 하고, 32명(55.17%)에서 스터지-웨버증후군을 진단 받았다. 안면화염혈관종과 연관된 녹내장은 2세 이전에 대부분 발병하였고 (85.61%), 모든 환자에서 녹내장이 발생한 눈과 같은 방향에서 안면화염혈관종을 보였다. 녹내장 수술의 평균 횟수는 1.55 ± 0.93회로 첫 수술로 섬유주절개술 7안(25.93%), 섬유주절제술 5안(18.52%), 섬유주절개술 및 섬유주절제술의 병합 13안(48.15%), 방수유출 장치삽입술 2안(7.41%)을 시행하였다. 첫 수술나이는 평균 35.14 ± 50.91개월이었고, 27안 중에서 18안(66.67%)은 수술 후 안압이 21 mmHg 미만으로 조절되었으나 9안(33.33%)은 안압 상승으로 추가적인 녹내장 수술을 시행하였다. 결론: 안면화염혈관종 환자에서는 안압이 상승하거나 녹내장이 동반될 수 있으므로 정기적인 안과검진이 필요하다. 또한 발생하는 녹내장은 약물치료에도 안압을 조절하기 어려운 경우가 있으며, 이 경우 적절한 녹내장 수술 시행이 필요하다. Purpose: To characterize the development of glaucoma, age of glaucoma onset, and treatments for patients with a facial port-wine stain (PWS). Methods: We performed a retrospective analysis of the medical records of 58 patients (116 eyes) with facial PWS between January 2000 and August 2016. We noted patients’ age at the initial examination, cup-to-disc ratio, corneal diameter, occurrence of ocular hypertension, development of glaucoma, age of glaucoma onset, and treatments. We compared the clinical features of eyes that developed glaucoma with those that did not develop glaucoma. Among those eyes with glaucoma, we investigated the differences between eyes that underwent surgery and those that did not undergo surgery. Results: Among the 58 patients with a facial PWS (116 eyes), glaucoma was diagnosed in 38 patients (46 eyes; 39.66%). Of these, 26 patients (27 eyes; 58.69%) underwent glaucoma surgery. PWS-associated glaucoma usually developed by the age of 2 years (85.61%). In all patients, glaucoma developed on the same side of the face as the PWS. Of the 58 patients, 19 (32.76%) showed neurological symptoms, including seizures, developmental delays, intellectual disabilities, or hemiplegia, and 32 (55.17%) were diagnosed with Sturge-Weber syndrome. The mean number of glaucoma surgeries was 1.55 ± 0.93. The initial surgery included trabeculectomy (7 eyes), trabeculotomy (5 eyes), combined trabeculotomy/trabeculectomy (13 eyes), and aqueous drainage device insertion (2 eyes). The mean age at the first surgery was 35.14 ± 50.91 months. In 18 of 27 eyes (66.67%), the postoperative intraocular pressure (IOP) was controlled to below 21 mmHg, but 9 eyes (33.33%) showed elevated IOP and required a reoperation. Conclusions: PWS can be accompanied by ocular hypertension or glaucoma, so patients require regular ophthalmic examinations. When glaucoma occurs, it often does not respond to medication, making it difficult in some cases to control the IOP, so appropriate glaucoma surgery is necessary. J Korean Ophthalmol Soc 2017;58(11):1234-1241

한국인 연소성개방각녹내장 환자에서 섬유주절제술의 장기 성적

오은규,이은지,정진욱,김석환,김태우,박기호,김동명.Eun Kyu Oh. MD. Eun Ji Lee. MD. Jin Wook Jeoung. MD. Seok Hwan Kim. MD.Tae-Woo Kim. MD. PhD. Ki Ho Park. MD. PhD. Dong Myoung Kim. MD. PhD 대한안과학회 2014 대한안과학회지 Vol.55 No.2

Purpose: To evaluate the outcomes and prognostic factors of trabeculectomy with mitomycin C in Korean patients with juvenile open-angle glaucoma (JOAG). Methods: A retrospective review was performed on 29 eyes with JOAG who had undergone trabeculectomy between January 2004 and January 2013. Intraocular pressure (IOP) and postoperative complications were monitored at 1 day preoperatively, at 1 day, 1 week, 1 month, 3 months, 6 months, and 12 months postoperatively, and at final follow-up after postoperative 18 months. Surgical success was defined as a final IOP of <21 mm Hg or <80% of preoperative IOP, regardless of the use of anti-glaucoma medication. Prognostic factors for surgical success or failure were analyzed by the Cox proportional hazards model. Results: Mean (± standard deviation) age at trabeculectomy was 24.6 (± 8.9) years, and mean follow-up period was 24.3 (± 20.8) months. The overall success rate was 82.8% at final follow-up. The Kaplan-Meier cumulative probabilities of surgical success were 100% at 1 year, 87.4% at 2 years, and 78.7% at 3 years postoperatively. The Cox proportional hazards model failed to determine any significant factors that were associated with surgical failure. The three most frequent postoperative complications were immediately postoperative hypotony (n = 19, 65.5%), hypotony maculopathy (n = 8, 27.6%), and encapsulated bleb (n = 8, 27.6%), most of which were resolved after a minor procedure or observation. Two of 8 eyes with encapsulated bleb required a second surgery. There were no vision-threatening severe complications. Conclusions: Trabeculectomy with MMC may be an effective treatment in Korean JOAG patients. J Korean Ophthalmol Soc 2014;55(2):252-260

수치해석을 이용한 팬 아웃 웨이퍼 레벨 패키지의 휨 경향 및 신뢰성 연구

이미경(Mi Kyoung Lee),정진욱(Jin Wook Jeoung),옥진영(Jin Young Ock),좌성훈(Sung-Hoon Choa) 한국마이크로전자및패키징학회 2015 마이크로전자 및 패키징학회지 Vol.21 No.1

최근 모바일 응용 제품에 사용되는 반도체 패키지는 고밀도, 초소형 및 다기능을 요구하고 있다. 기존의 웨이퍼 레벨 패키지(wafer level package, WLP)는 fan-in 형태로, I/O 단자가 많은 칩에 사용하기에는 한계가 있다. 따라서 팬 아웃 웨이퍼 레벨 패키지(fan-out wafer level package, FOWLP)가 새로운 기술로 부각되고 있다. FOWLP에서 가장 심각한 문제 중의 하나는 휨(warpage)의 발생으로, 이는 FOWLP의 두께가 기존 패키지에 비하여 얇고, 다이 레벨 패키지 보다 휨의 크기가 매우 크기 때문이다. 휨의 발생은 후속 공정의 수율 및 웨이퍼 핸들링에 영향을 미친다. 본 연구에서는 FOWLP의 휨의 특성과 휨에 영향을 미치는 주요 인자에 대해서 수치해석을 이용하여 분석하였다. 휨을 최소화하기 위하여 여러 종류의 epoxy mold compound (EMC) 및 캐리어 재질을 사용하였을 경우에 대해서 휨의 크기를 비교하였다. 또한 FOWLP의 주요 공정인 EMC 몰딩 후, 그리고 캐리어 분리(detachment) 공정 후의 휨의 크기를 각각 해석하였다. 해석 결과, EMC 몰딩 후에 발생한 휨에 가장 영향을 미치는 인자는 EMC의 CTE이며, EMC의 CTE를 낮추거나 Tg(유리천이온도)를 높임으로서 휨을 감소시킬 수 있다. 캐리어 재질로는 Alloy42 재질이 가장 낮은 휨을 보였으며, 따라서 가격, 산화 문제, 열전달 문제를 고려하여 볼 때 Alloy 42 혹은 SUS 재질이 캐리어로서 적합할 것으로 판단된다. For mobile application, semiconductor packages are increasingly moving toward high density, miniaturization, lighter and multi-functions. Typical wafer level packages (WLP) is fan-in design, it can not meet high I/O requirement. The fan-out wafer level packages (FOWLPs) with reconfiguration technology have recently emerged as a new WLP technology. In FOWLP, warpage is one of the most critical issues since the thickness of FOWLP is thinner than traditional IC package and warpage of WLP is much larger than the die level package. Warpage affects the throughput and yield of the next manufacturing process as well as wafer handling and fabrication processability. In this study, we investigated the characteristics of warpage and main parameters which affect the warpage deformation of FOWLP using the finite element numerical simulation. In order to minimize the warpage, the characteristics of warpage for various epoxy mold compounds (EMCs) and carrier materials are investigated, and DOE optimization is also performed. In particular, warpage after EMC molding and after carrier detachment process were analyzed respectively. The simulation results indicate that the most influential factor on warpage is CTE of EMC after molding process. EMC material of low CTE and high Tg (glass transition temperature) will reduce the warpage. For carrier material, Alloy42 shows the lowest warpage. Therefore, considering the cost, oxidation and thermal conductivity, Alloy42 or SUS304 is recommend for a carrier material.