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      • KCI등재
      • SCOPUSKCI등재

        임상연구 : 중화상 환자에서 Mivacurium의 신경근 약역학

        정미화 ( Mi Hwa Chung ),정진경 ( Jin Kyung Jung ),이진영 ( Jin Young Lee ),곽인숙 ( In Suk Kwak ),최영룡 ( Young Ryong Choi ),원임수 ( Rim Soo Won ),한태형 ( Tae Hyung Han ) 대한마취과학회 2006 Korean Journal of Anesthesiology Vol.51 No.5

        Background: Burned patients sometimes require rapid onset of neuromuscular paralysis to secure the airway in full stomach patients or to treat laryngospasm. Because of poor lung function and hypermetabolic state, they desaturate quite rapidly. Burned patients are usually resistant to the effects of nondepolarizing relaxants. Mivacurium can be potentially a good alternative for rapid onset of paralysis, since it is metabolized by plasma cholinesterase, an enzyme often decreased in subject with major burns. This prospective study was conducted to define the neuromuscular pharmacodynamic profile of a single bolus dose of mivacurium in adult patients with major burns. Methods: Adults (M/F = 22/8), aged 44.0 ± 10.2 years, with total body surface area (TBSA) burn of 35.0 ± 12.5% were studied at 39.8 ± 28.9 post burn days. Age and sex matched 30 non-burned patients served as controls. Anesthesia was consisted of propofol and fentanyl infusion with nitrous oxide and oxygen. Mivacurium 0.2 mg/kg was administered as a bolus. Using TOF Watch, neuromuscular block was monitored with T1 response after the initial tetanic stimulation to recruit all muscle fibers. Onset time was defined as the interval from the beginning of drug administration to maximal twitch suppression. Intubation was attempted at 1 minute after the drug administration to simulate the rapid sequence induction with recording of either failure or success of intubation. By allowing spontaneous recovery without reversal drug, recovery profiles of neuromuscular paralysis were also measured. Results: Patients demographics were similar in both groups except for the burn. Onset times and all recovery profiles were significantly prolonged in the burned versus non-burned groups. Attempts at intubation at 1 minute after the drug administration were successful with difficulty in approximately 70% of patients in both groups. Conclusions: Mivacurium 0.2 mg/kg demonstrated the conflicting dual responses in the burned patients. The prolonged onset time suggests resistance to neuromuscular effects. The prolonged recovery suggests increased sensitivity. This can be partially explained by the acetylcholine receptor proliferation and decreased level of plasma pseudocholinesterase. In view of the prolonged onset time of almost two minutes for maximal paralysis, mivacurium does not appear to be a good drug for rapid onset of paralysis in burns. (Korean J Anesthesiol 2006; 51: 541~6)

      • KCI등재

        체외수정 후 일측 두개 뇌류를 동반한 쌍태 임신에서 임신 중반기 선택적 유산

        한경희 ( Kyoung Hee Han ),한혁동 ( Hyuk Dong Han ),홍민 ( Min Hong ),이향아 ( Hyang Ah Lee ),정진경 ( Jin Kyung Chung ),김나옥 ( Na Ok Kim ) 대한산부인과학회 2003 Obstetrics & Gynecology Science Vol.46 No.2

        Selective termination can be used to preserve normal fetus from the other fetus with chromosomal, structural abnormality in multifetal pregnancy. This case is about twin pregnant patient who had undergone in vitro fertilization and embryo transfer. In 18

      • KCI등재

        고로조업조건에서 냉각용 Cu 스테이브의 마모특성

        김장원 ( Jang Won Kim ),박종인 ( Jong In Park ),이기우 ( Ki Woo Lee ),권의혁 ( Eui Hyuk Kwon ),김강민 ( Kang Min Kim ),권재홍 ( Jae Hong Kwon ),정진경 ( Jin Kyung Chung ),최태화 ( Tae Hwa Choi ),한정환 ( Jeong Whan Han ) 대한금속재료학회(구 대한금속학회) 2015 대한금속·재료학회지 Vol.53 No.5

        Blast furnace is generally known for iron mass production vessel with a long campaign life. However during the blast furnace operation, erosion of inner wall by the burden descent is unavoidable and it becomes the most important factor for determining the campaign life of the blast furnace. Lining of the furnace is composed of refractory and cooling Cu stave. Due to the erosion of the refractory brick, the Cu stave built in the refractory brick is exposed after several years use of the furnace. Wear of stave surface is then accelerated by the burden descent rapidly especially at high temperature and high pressure condition. Therefore, wear characteristics of Cu stave are needed to be predicted. Wear of Cu samples is tested at high temperature friction conditions using a ring-on-disc type on custom-built equipment. The wear conditions by burden descent could be changed by the operating temperature and pressure of furnace, coke particle size, hardness of Cu in high temperature, and the cooling temperature, etc. The experimental results are used to predict the life of blast furnace through the measurement of Cu wear loss.

      • SCOPUSKCI등재

        Oxy - coal 버너 사용이 연소대 온도에 미치는 영향

        박판욱,정진경 한국화학공학회 1998 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.36 No.5

        Oxy-coal 버너를 사용하여 미분탄 최입을 하는 경우 고로 연소대 온도를 측정하고 연소대 반경방향의 온도에 미치는 영향을 고찰하였다. 연소대 온도 측정은 고로 휴지시 코크스 샘플링을 통해 얻어진 코크스의 XRD분석, R-type 열전대를 이용한 직접측정, 2색 고온 온도계를 이용한 연소대 온도 최고점 측정을 통해서 이루어 졌으며, oxy-coal 버너를 사용시 버너선단 주위 산소농도를 실험실적으로 측정하였다. 이러한 연소대에서 온도 및 산소성분의 거동을 파악하기 위해서 연소대에서 oxy-coal 버너 사용시 코크스와 미분탄의 연소반응을 고려한 1차원 연소모델을 사용하여 연소대 반경방향의 온도 및 성분분포를 구하였으며 위의 측정값과 비교한 결과 매우 잘 일치하는 것을 알 수 있었다. Oxy-coal injection effects on blast furnace raceway temperature were discussed based on coke sampling experiments through the tuyere of blast furnace, measurement by R-type thermocouple and two-color pyrometer. To analyze the reason for the increase of coal combustion ratio by oxy-coal injection, the oxygen concentration was measured in the simulated experimental of oxy-coal burner. The one-dimensional mathematical model considering the kinetics of coal and coke combustion was developed in other to simulate the combustion characteristics, such as gas temperature and composition in the raceway. It was found that the calculated peak temperature of gas well concurred with the measured temperature according to oxygen enrichment through the oxy-coal burner.

      • SCOPUSKCI등재

        고로에서 분의 거동에 미치는 미분탄 취입의 영향

        박판욱,정진경,허완욱 한국화학공학회 1999 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.37 No.5

        고로공정에서 미분탄 취입량에 따라 증가되는 노내 발생분의 기원파악과 정량화를 위해서 여러 가지 시험을 실시하였다. 고로내에 퇴적된 분과 고로외로 배출된 분을 채취하여 성분분석과 열중량분석, SEM분석 및 메틸렌 요오드를 이용한 중액분리 방법을 통하여 물리적으로 미연소 미분탄을 선별한 결과 미연소 미분탄과 코크스분이 혼재하는 것을 확인하였다. XRD 분석에 의해 결정질 탄소와 비정질 탄소 피크의 상대강도 크기를 비교분석하므로서 코크스 및 미분탄에서 기원한 탄소의 분류가 가능하였다. To investigate on the reasons for the fines increase with PCR, several analyses such as TGA, SEM and separation by heavy medium are carried out for blast furnace wet dust and fines obtained by coke sampling. The results show that the fines are composed of unburned pulverized coal and coke. The contribution of char and carbon contents in char and coke fines changes with coal combustibility. It is concluded that the origin of carbon source, coke or coal, can be discriminated by the relative intensity of graphite peak in XRD carbon analysis.

      • KCI등재

        미분탄취입이 고로연소대 거동에 미치는 영향

        김태동,한창환,정진경 대한금속재료학회(대한금속학회) 1994 대한금속·재료학회지 Vol.32 No.2

        Coal injection effects on the behavior of a blast furnace raceway were discussed based on analyses of operating parameters and coke sampling experiments through the tuyere of the blast furnace as well as one-dimensional mathematical simulation of coal combustion characteristics in the raceway. Coke sampling lance was inserted through the tuyere during the shut-down of blast furnace to measure the raceway depth. It was revealed that the raceway depth decreases with the increase of coal injection rate, which could result in the increase of wall temperature and gas permeability resistance at the lower part of the furnace. The one-dimensional mathematical model considering the kinetics of coal and coke combustions was developed in order to simulate the combustion characteristics, such as gas temperatures and compositions in the raceway. It was found that the calculated peak temperature of gas way similar to the adiabatic flame temperature which is one of the operating parameters, and that the calculated effects of blast temperature, moisture addition and oxygen enrichment on the gas temperature except the coal injection rate were well matched with the changes of adiabatic flame temperature.

      • KCI등재

        정상상태 고로에 미치는 미분탄 취입의 영향

        김정희,박판욱,정진경,허완욱,정용옥 한국화학공학회 2002 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.40 No.2

        미분탄 취입(pulverized coal injection; PCI)은 고로 내부의 분 축적을 가중시킨다. 특히 고로 하부에서 축적된 미연소 미분탄은 연소대 심도를 감소시키고 데드맨의 기체흐름을 저하시켜, 고로의 정상상태에 영향을 준다. 기체와 고체의 흐름 그리고 각 고체층에 상당하는 반응을 고려한 물질전달과 열전달로 모형화한 고로 내부 현상들은 유한요소법(Finite Element Method; FEM)을 사용하고, 철광석의 환원율 모형은 전진 차분법(Forward Euler Method)을 사용하여 수치해석하였다. 연소대의 심도감소와 데드맨의 기체흐름저하는 모두 충진층 내의 압력강하를 증가시키고 고로 내부의 온도를 감소시킨다는 점에서는 비슷하였다. 그러나 데드맨의 기체 흐름 감소가 단지 고로 하부 온도만 감소시켰다. 이에 반해, 연소대의 심도 감소는 고로의 전체 평균온도를 저하시키고, 연소대 경계의 기체흐름을 증가시켜 노벽측 보쉬 부근의 고체온도를 상승시킨다. 따라서 철광석의 연화융착이 축 중심부에서 낮게 형성되고 노벽측에서는 높게 나타난다. 그 결과 연화융착대의 길이가 감소하여 기체흐름과 고로의 상태에 나쁜 영향을 미친다. A pulverized coal injection increases the accumulation of fines in a blast furnace. The accumulation of fines in the lower part of the blast furnace diminishes the size of the raceway depth and gas flow into the deadman and, as a result, affects the steady state condition of the blast furnace. The state of the blast furnace, which depends on the gas and solid flow, chemical reactions, mass transfer and heat transfer, is numerically analyzed using a FEM (finite element method). But the ore reduction index model, which estimates the chemical state of ore in blast furnace, is made using Forward Euler method. The decrease in both the size of the raceway depth and the gas flow into the deadman results in increasing pressure drop and lowering the average temperature in the blast furnace. However the reduction of gas flow into deadman affects in only the lower part of the furnace, but the diminution of the raceway depth decreases the average temperature in the entire furnace, even though the solids on the upper raceway become hotter due to increasing gas flux through the raceway. So, the melting position is lowered in axial direction at center of blast. As a result the length of the cohesive zone is shortened to give permeability resistance on the gas flow and to make the furnace operation unstable.

      • SCOPUSKCI등재

        Finite Element Method 에 의한 고로내 분거동 해석

        김정희,박판욱,정용옥,정진경 한국화학공학회 2001 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.39 No.1

        미분탄 취입량 증가와 함께 고로내에서 분의 거동은 조업상태를 결정하는 중요한 요소가 되었다. 유동 층진층의 일종인 고로내에서 분농도 분포를 추정하기 위해서 Ergun식을 활용하여 고로내 가스유속 및 압력분포를 FEM(Finite Element Method)에 의해서 2차원으로 해석하였다. 분의 거동 해석은 분과 층진입자간 충돌저항력과 중력에 의한 저항 등을 고려한 모멘텀 밸런스를 구한후 실험실적으로 구한 분속도 추정식과 결합하여 해석하였다. 해석 결과 층진층내에서 분의 축적량을 결정하는 데 있어서 분입도, 분발생량 및 분 밀도 순으로 영향을 미치는 것을 알 수 있었다. 풍구를 통해 샘플링된 분의 농도는 수치 해석에 의해서 구한 농도값과 비교한 결과 매우 잘 일치하였으며 분 농도가 10%가 되는 지점은 1.5-2 m정도가 되는 것으로 나타났다. 분의 농도가 높은 지역은 노심내로서 20-30%를 나타냈으며 연화융착대 부분과 연화융착대 직상의 벽부에서는 10-20%의 분 농도를 나타냈다. Fines behaviors are considered as main factors in determining the operation states of blast furnace with PCI(Pulverized Coal Injection). The gas velocity and pressure distribution in blast furnace was analyzed by Ergun equation with two dimensional FEM(Finite Element Method). The theoretical model to predict the pressure drop was used under assumption that the interaction force between gas and powder is main resistance factor in fines flow through packed bed. To estimate the powder hold-up, the model is combined with the experimental result on the fines velocity in gas stream. The size of fines is most important factor in determining the concentration of fine in blast furnace together with density and feeding rate. Both of the measured and calculated results show that 10% fines concentration is at 1.5-2 m distance from tuyere tip. The results of 2-D numerical analysis on the distribution of fines concentration in blast furnace shows 20-30% in deadman and 10-20% above the root of cohesive zone.

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