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W/O 제형에 의한 화장품용 마이크로바이오젤의 One-step 제조
정원욱,서상권,이의정,오주영,판보해,김형일,이경진 한국고분자학회 2023 폴리머 Vol.47 No.4
Microbiogels are biocompatible and biodegradable, so they have various biomedical applications such as drug delivery and their manufacturing methods. However, it has drawbacks such as unstable yield, multi-step procedure, and cumbersome separation process. This study presented a simple one-step method for preparing microbiogel directly during water-in-oil (W/O) emulsion manufacturing process of cosmetics. We controlled the critical gelation temperature (Tgel) of biogel by carrageenan and polyol content and the particle size of microbiogels in emulsions by food emulsifier content. We moniter the release of encapsulated gelatin in microbiogel over Tgel and find the release of the encapsulants can be regulated by controlling the temperature. We find this microbiogel increases the complex modulus (G*) of emulsion. This one-step method is of great value in the study of W/O cosmetic formulations that can encapsulate various active ingredients in microbiogels.
정원욱,최영태,서무교,박응수,손병기 경북대학교 센서기술연구소 1990 센서技術學術大會論文集 Vol.1 No.1
In this paper, pH-meter signal processing system using ISFET(Ion Sensitive Field Effect Transistor), based on single chip MCU(Micro Controller Unit), is designed and fabricated. The reliability and operational characteristics of this system was measured, compared with conventional pH-meter using ISE(Ion Slective Electrode). The method of temperature compensation that this system adapt is to process output of temperature sensor(AD590). The pH-meter with ISFET have good sensitivity, about 53 mV/pH, and showed excellent linearity in the range of pH 2 to pH 12. We certified that this system can used for pH mesurement system using ISFET as pH sensor.