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구연 / 제 3 회의장 / 간 30 : 위 - 식도 정맥류 출혈에 대한 치료로서 경목정맥 간내 문맥 간정맥 단락술 후 재출혈과 간성뇌병증의 발생 및 사망에 관련된 인자들의 분석
장영우(W . Y . Jang),정영화(Y . H . Chung),송병철(B . C . Song),양수헌(S . H . Yang),이한주(H . C . Lee),윤현기(H . K . Yoon),성규보(K . B . Sung),이영상(Y . S . Lee),서동진(D . J . Suh) 대한소화기학회 1999 대한소화기학회 추계학술대회 Vol.1999 No.-
진행성 전신경화증 환자에서 식도관련증상과 식도 운동성과의 상호관계
송인성(I S Song),최규완(K W Choi),김정룡(C Y Kim),정영화(Y H Chung),이풍렬(P L Rhee),정현채(H C Jung),송영욱(Y W Song),이효석(H S Lee),윤용범(Y B Yoon) 대한소화기학회 1988 대한소화기학회지 Vol.20 No.3
N/A To investigate the correlation of esophageal symptoms w ith esophageal manometric parameters in patients with progressive systemic sclerosis (PSS) we tested esophageal motility in 10 patients with PSS who were admitted to Seoul National University Hospital from Feb. 1988 to Aug. 1988 and in 5 normal subjects, and we analyzed every parameters. The results were as follows: 1) 4 patients with esophageal symptoms showed marked decrease of lower esophageal sphincter pressure (LESP) (9.I+4.4 mmHg vs 27.9+8.5 mmHg; p< 0.005) while 6 patients having no esophageal symptoms showed normal LESP (29.4+4.0 mmHg vs 27.9+8.5 mmHg). 2) Normally propagating peristaltic waves were not found in the lower esophageal bodies of 4 patients who had esophagea] symptoms. On the other hand, among 6 patients without symptoms, 3 patients showed no propagating peristaltic waves while the other 3 patients showed normally propagating peristaltic waves in the lower esophagus. 3) The amplitudes of contraction waves at upper esophageal body of patients with esophageal symptoms were decreased compared with those of patients who had no esophageal symptom. (29.0+6.1 mmHg vs 21.0+4.4 mmHg; p<0.05) 4) In cases not showing normally propagating peristaltic waves, nonpropagating, hroad-based, low-amplitude contractions were found at the lower esophageal body. In conclusion, LESP is the esophageal manornetric parameter vhich seemed to be the most closely correlated with esophagea) symptoms in patients with PSS. And PSS seems to influence the upper esophageal contraction. Our data also indicates that esophageal manometry may be useful in the early detection of esophageal involvement in patients with PSS.
계통발생에 따른 척추동물의 뇌후구에 대한 전자현미경적 연구
최명봉,정영화,서지은,Choi, W.B.,Chung, Y.H.,Seo, J.E. 한국현미경학회 1985 Applied microscopy Vol.15 No.2
Authors are trying to unveil the ultrastructural organization of olfactory bulb, which has been summerized under light microscopic level or communicated only in some detail in different view point until now. For the critical point of view, since the phylogenetical approach will give the ultimate value in the correlative study between structural and functional bases (Brodal, 1969), the present study was carried out light and electron microscopic analyses of the structures of the neurons and synaptic organizations in olfactory bulbs from different animals in phylogenetical scale. We selected each one species from five animal classes: the house rabbit(Oryctolagus cuniculus var. domesticus [Gmelin]) from Mammalia, the domestic fowl (Gallus gallus domesticus Brisson) from Aves, the viper (Agkistrodon hylys [G.P. Pallas]) from Reptilia, a frog (Bombiana orientalis Boulenger) from Amphibia and the crussian carp (Carassius carassius [Linne]) from Pisces. For light microscopic study, samples were fixed in 10% formalin and paraffin sections were stained with hematoxylin-eosin. For the electron microscopic study, the tissues were fixed by perfusion through the heart or immersion with 1% paraform-aldehyde-glutaraldehyde mixture (phosphate buffer, pH 7.4), and final tissue block trimmed under dissecting microscope were osmicated (1% OsO4), they were embedded in Araldite or Epon 812, and ultrathin sections were made by LKB-V ultratome following the inspection of semi-thin sections stained with toluidine blue-borax solution. Ultra-thin sections contrasted with uranyl acetate and lead citrate were observed with JEM 100CX electron microscope. We have summerized our morphological analyses as follows: 1. The olfactory bulb of rabbit, viper and frog shows the eight layers of fila olfactoria, glomerular, external granular, external plexiform, mitral cell, internal plexiform, internal granular, medullary but domestic fowl shows the five layers of glomerular, fibrillar, mitral, granular and medullary and the three layers of fibrilla, glomerular and medullary in crussian carp. The sharpness of demarcation between the layers shows deferential tendency according to phylogenetical order. 2. Mitral cells of vertebrate have large triangular or oval shape with spherical nuclei which contain not so much chromatin. The cytoplasm contains numerous cell organelles, of which Nissl's bodies or granular endoplasmic reticula arranged as parallel strands. Development of granular endoplasmic reticula were declined as the phylogentical grade is going lower. 3. Tufted cells of all animal are mostly spindle or polygonal contour and contain oval nuclei which located in periphery of cytoplasm. The nuclei of rabbit, fowl, viper and frog has relatively space chromatin, but a nucleus of crussian carp contain irregularly aggregated chromatin in karyoplasm. Their cytoplasmic volume and cell organelle contents are in between those of mitral cell and granular cell. They contain moderate amount of mitochondria, granular endoplasmic reticula, a few Golgi complex, polysomes, lysosome, etc. 4. Granule of cells of all the vertebrate amimals studied exhibit similar features; cells and their dense nuclei show spherical or oval contour, and they have the thin rim of cytoplasm which contain only a few cell organelles. 5. In rabbit, the soma of mitral cells were in contact with boutons with two types of synaptic vesicles, that is, round and flat vesicles, especially flat vesicles in boutons were showing reciprocal synapses. However, in domestic fowls, vipers, frogs and crussian carps, there were found boutons showing only spherical synaptic vesicles. 6. The boutons containing round synaptic vesicles were made contact with the some of tufted cell of olfactory bulb in the rabbits, fowls, vipers and frogs, but no synaptic boutons were observed in soma of tufted cells in crussian carps. In the frogs, there were observed dendrites were contact with the soma of tufted cells. 7. In the neuropil