백서에서 유발된 염증에 대한 Triamcinolone Acetonide 이온도입 경피투과 효과

정대인,김태열,김계엽,김명훈,Jung Dae-In,Kim Tae-Youl,Kim Kye-Yoep,Kim Myong-Hoon 대한물리치료학회 2003 대한물리치료학회지 Vol.15 No.2

This study investigated the effects of triamcinolone acetonide by iontophoretic transdermal drug delivery on anti-inflammatory action into the rats and which had carrageenan-induced hyperalgesia and edema in the feet, trauma-induced tissue damage in the thigh. Each group was treated under the fellowing conditions. 1. Group I : Control group 2. Group II : Application of direct current 3. Group III : Application of 0.1$\%$ triamcinolone acetonide solution 4. Group IV : Iontophoresis of 0.1$\%$ triamcinolone acetonide solution The degree of anti-inflammation was evaluated by the paw withdrawal latency, the change in volume of foot the change of paw edema, histological change in rats. 1. In paw withdrawal latency, group IV showed the most significant therapeutic effect than the other groups at 0, 3, 6 and 9 hours(p < 0.001). 2. In paw edema experiment in the foot, group IV showed the most significant effect than group I at 0, 3, 6 and 9 hours. It meant that there was effective anti-inflammatory reaction in group I (p < 0.001). 3. In the light microscopic observation, group IV showed the most significant reduction of haemorrhage, hyperemia and infiltrative inflammation. From the results, the iontophoresis with triamcinolone acetonide is more effective than using each groups. It is one of the effective physical agent which delivered large molecular weight drug into the body. The continuous study is needed for many interesting issues of iontophoretic transdermal drug delivery in new future.

지연성 근육통에 대한 Triamcinolone Acetonide의 이온도입 경피투과

정대인,김명훈,황태연,윤세원,최은영,Jung, Dae-In,Kim, Myong-Hoon,Hwang, Tae-Yeun,Yoon, Se-Won,Choi, Eun-Young 대한임상전기생리학회 2003 대한임상전기생리학회지 Vol.1 No.1

This study investigated the effects of triamcinolone acetonide by iontophoretic transdermal drug delivery on anti-inflammatory action into the human which had excentric exercise-induced delayed onset muscle soreness in the non-dominant arm. The degree of anti-inflammation was evaluated creatine posphokinase(CPK) by serum enzyme activity and subjective pain threshold by soreness muscle scale in clinical study. The results Were as follows; 1. In a subjective pain scale, all groups showed non-significant difference but, showed a tendency to decrease numerical value in human. 2. In the serum CPK level, iontophoresis group showed more significant reduction than other groups at 24, 48 and 72 hours. From the results, the iontophoresis with triamcinolone acetonide is more effective than using each groups. The continuous study is needed for many interesting issues of iontophoretic transdermal drug delivery in new future.

노인장기요양보험제도 내 가정방문물리치료 도입에 관한 인식도 및 필요성 조사

정대인(Dae-In Jung),김찬규(Chan-Kyu Kim),고대식(Dae-Sik Ko) 한국콘텐츠학회 2014 한국콘텐츠학회논문지 Vol.14 No.6

본 연구는 노인장기요양보험제도에서 가정방문물리치료 제도의 도입과 정착을 위해 수급자 측면의 환자와 공급자 측면의 물리치료사의 인식 및 필요성에 대한 의견을 알아보고자 하였다. 조사 참여자는 광주광역시 소재 의료기관에 근무하는 물리치료사(130명)와 환자(96명)를 대상으로 설문조사를 실시하였다. 연구결과 환자(60.4%)와 물리치료사(75.4%)는 장기요양보험제도에서 간호사 및 간호조무사에 의해 제공되는 신체활동 지원서비스는 전문성이 부족하며, 가정방문물리치료를 통해 질적인 치료가 가능할 것이라고 응답하였다(환자 47.9%,물리치료사 59.2%). 또한 장기요양보험제도 개선 시 가장 우선순위에 대한 질문에서 환자는 급여비 절감(35.4%)과 대상자 확대(32.3%),치료사는 전문인력 확대(73.8%)와 다양한 재활서비스의 도입(20.2%)순으로 응답하였고,재활팀의 도입이 필요하다고 응답하였다. 가정방문물리치료가 필요한 이유는 환자가 의료기관에 가기 힘듦(PT 30.0%)과 노인의 신체기능이 향상(pt47.1%)되기 때문이라고 응답하였다. 결론적으로 물리치료사뿐만 아니라 수요자인 환자 대부분에서 노인장기요양보험제도 내에 가정방문물리치료 도입에 관한 필요성 및 인식도가 현저히 높은 것으로 나타나 제도의 시행이 시급한 것으로 판단된다. This study aims to investigate the awareness and needs of patients as consumers and therapists as providers on the introduction of home physical therapy in the long-term care insurance. The survey participants were 96 patients and 132 physical therapists to a questionnaires, we analyzed for frequency of each questionnaire about awareness and necessity. As a result of the test, they considered that physical activity support services provided by nurse and nurses aid ware not specialized enough(pt60.4%, PT 75.4%) and quality therapy should be available through a home physical therapy(pt47.9%, PT 59.2%). Also, patients responded that the priorities to improve long-term care insurance were given to lowering expenses(35.4%) and expanding coverage of subjects(32.3%) while the physical therapists responded that professionals should be expanded(73.8%) and diverse rehabilitation services(20.2%) and a rehabilitation team should be introduced. They responded that the reasons of home physical therapy were needed that it was hard for patients to visit medical centers(PT 30.0%) themselves and it would be improvable for them to get physical function in elderly(pt47.1%) through the service. In conclusion, as most patients as well as physical therapists responded that home visit therapy services should be introduced and their awareness of it was very high, it is suggested that the service should be quickly introduced as soon as possible.

가상현실 체험형 운동과 요부안정화운동에 따른 뇌졸중환자의 낙상관련 신체․심리적 비교 분석

정대인(Dae-In Jung),서태화(Tae-Hwa Seo),고대식(Dae-Sik Ko) 한국콘텐츠학회 2012 한국콘텐츠학회논문지 Vol.12 No.8

이 연구는 뇌졸중 환자를 대상으로 낙상예방을 위하여 가상현실 체험형 게임 운동(Nintendo-Wii Sport-NWS)과 요부안정화 운동을 실시하고 낙상관련 신체?심리 기능 변화를 측정하였다. 뇌졸중환자 30명을 대상으로 신체적 기능은 정적, 동적균형으로 측정하였고 심리적기능은 낙상효능감을 측정하여 운동 전과 운동 후, 각 운동군간을 비교분석하였다. 정적균형은 BBS, FRT, 동적균형은 TUG, 10m 보행검사, 낙상효능감은 낙상 효능감 지수로 측정되었다. 그 결과 두군 모두 신체?심리적기능에서 유의한 개선을 나타내었다. 그러나 BBS, FRT, 10m보행에서 요부안정화 운동군이 더 통계적으로 개선된 것으로 나타났으며 낙상효능감은 가상현실 체험형 게임 운동 군에서 더욱 개선된 것으로 나타났다. 결론적으로 가상현실 체험형 게임운동은 뇌졸중환자의 신체?심리적 기능 증진에 긍정적인 영향을 미친다. This study conducted the following experiment to examine change of physicopsychological function on lumbar stabilization exercise(LSE) and virtual reality game training(Nintendo Wii Sport-NWS) to stroke patients subject for fall prevention. Psychological function was measured by falls efficacy with stroke patients and physical function was measured by static and dynamic balance on comparative analysis of pre, post exercise and each groups in 30 stroke patient subject. Static balance was measured by BBS, FRT, dynamic were measured by TUG, 10m walking test and falls efficacy with stroke patients was measured index of falls efficacy. These result lead us to the conclusion that each group were statistically improved at all physicopsychological test. but BBS, FRT, 10m walking test were more statistically improved at LSE group and falls efficacy with stroke patients were more improved at virtual reality game training group. Consequently, virtual reality game training would be lead to positive increment of physico sychological function on stroke patient.

음악 템포에 따른 유산소 운동이 스트레스 요소에 미치는 효과

정대인(Dae-In Jung),장일용(Il-Yung Jang),이은상(Eun-Sang Lee) 대한심장호흡물리치료학회 2020 대한심장호흡물리치료학회지 Vol.8 No.1

Purpose : The purpose of this study is to assess changes in the circulatory system according to the tempo of music while performing treadmill exercises. Methods : This study selected a total of 21 healthy students (ten male and eleven female) in the department of physical therapy at Gwangju Health University. Participants exercised for 30 minutes once a week for a total of three weeks. Participants’ heart rate, autonomic nervous system activity, and blood pressure were measured at pre-test and post-test intervals. In the first week, treadmill exercise was completed without music. In the second week, we applied slow tempo music (60~80 bpm) while using the treadmill, and in the third week, we applied fast tempo music (120~140bpm). The measured data were analyzed by repeated-measurements ANOVA using the before and after values for each music tempo. The results are displayed as differences between the three groups. Results : There were no significant differences in heart rate, systolic blood pressure, diastolic blood pressure, or RMSSD (autonomic nervous system) between the three groups. There was a significant difference in LF/HF (autonomic nervous system) between the three groups. Conclusion : According to our results, there was some evidence for music tempo benefiting the autonomic nervous system during exercise. However, there is a need for more study on this subject. Continued research on this subject could provide benefits to the science of physiotherapy as it relates to cardiopulmonary treatment.

뉴노멀 시대의 ‘소수적인 신학’(Minority theology)에 관한 소고 - 질 들뢰즈의 소수성을 중심으로

정대인(Dae-in Jung) 한국기독교학회 2021 한국기독교신학논총 Vol.122 No.-

전지구적 자본주의 문명이 야기한 기후변화와 생태계 파괴는 결국 코로나 바이러스를 통한 팬데믹 사태를 불러왔다. 한국 사회는 이제 팬데믹이라는 부정적인 것과 함께 머물기를 준비해야 하는 시점에서 사회 전반의 표준에 대한 재성찰을 요구하고 있다. 이런 취지에서 본 소고는 제도화된 기독교의 표준을 비판적으로 고찰하며, 기독교의 뉴노멀을 질 들뢰즈(Gilles Deleuze)의 소수성을 중심으로 재구성하고자 한다. 들뢰즈에게 소수성은 표준화/균일화 같이 정해진 영토를 벗어나는 창조와 생성의 탈영토화(deterritorialization)를 의미한다. 본고에서는 기독교의 표준을 추동하는 보편성과 초월성의 신학을 ‘다수적인 신학’(majority theology)으로 규정하며, 이를 ‘소수적인 신학’(minority theology)과 대비시킨다. 소수적인 신학은 제도화된 기독교의 표준을 벗어나는 흐름을 의미하며, 본 소고에서는 1) 감응의 존재론 2) 내재성의 구도를 뉴노멀 시대의 기독교 신학의 새로운 조건으로 제언하고자 한다. Climate change and ecological destruction led by a global capitalist civilization eventually gave rise to the COVID-19 pandemic. At this very moment, Korean society has the need to acknowledge that it must prepare for a “tarrying with the negative” of the pandemic, and as such, is currently pushing for a re-examination of the notion of ‘normal’ in society as a whole. This paper critically reviews the norms of institutionalized Christianity and attempts to organize the New Normal of Christianity centered on the concept of a minority developed by Gilles Deleuze. Deleuze argues that minority means the deterritorialization of creation and formation that go beyond the prescribed territory such as norms/uniformity. This paper prescribes the ideological and transcendental theology that drives this form of norms in Christianity as a ‘majority theology’ and contrasts it with ‘minority theology’. Minority theology can be defined through the flows that deviate from the norms of institutionalized Christianity. The present study suggests 1) an ontology of affect, and 2) the plane of immanence: as the characteristics of minority theology, and proposes these elements as the new conditions for Christian theology in the age of the New Normal.

발성훈련과 병합된 복합 호흡운동이 호흡근 및 폐기능에 미치는 효과

정대인(Dae-In Jung),이한결(Han-Gyeol Lee) 대한심장호흡물리치료학회 2020 대한심장호흡물리치료학회지 Vol.8 No.2

Purpose : This study aims to investigate the effect of complex breathing exercises combined with vocal training on respiratory muscle and pulmonary function. Methods : A total of 39 college students (17 men and 22 women) were enrolled in this study. The subjects were divided equally into three groups as follows: Group 1: breath training (13), Group 2: vocal training (13), and Group 3: both breath and vocal training (13). The exercise programs were conducted over an eight-week period. Group A received training on thoracic mobilization in four directions and abdominal breathing. Group B received training on reading written text and how to use vocal cords. Group C received training on both methods. Micro Quark (Cosmed, Italy) was used to measure breathing ability, and 2EM (4D-MT, Relive, Gimhae, Korea) was used to measure muscle activity of all groups before and after intervention. Results : In this study, the results showed that there were no significant differences in interaction effect of pulmonary function and muscle activity between the three groups. There was a significant difference in the main effect before and after intervention. Conclusion : According to our results, there was some evidence for the effect of complex breathing exercises combined with vocal training on respiratory muscle and pulmonary function. However, more studies on this subject are needed. Continued research on this subject could provide benefits to the science of physiotherapy as it relates to cardiopulmonary treatment.

만성 폐쇄성 폐질환을 위한 자가 관리 호흡운동의 최근 동향 : 체계적 고찰 및 메타분석

정대인(Dae-In Jung),김현중(Hyun-Joong Kim) 대한심장호흡물리치료학회 2021 대한심장호흡물리치료학회지 Vol.9 No.1

Purpose : In self-management of chronic obstructive pulmonary disease (COPD), breathing exercises can effectively improve respiratory muscle strength and endurance, correct abnormal thoracic spine and abdominal motions, and reduce dyspnea and dynamic hyperinflation. In this systematic review and meta-analysis, we aimed to examine recent trends in self-management breathing exercises for patients with COPD. Methods: We searched the MEDLINE, EMBASE, CINAHL, PEDro, and CENTRAL databases until March 2021 for randomized controlled trials (RCTs) evaluating pulmonary function and exercise capacity through self-management breathing exercises (BEs) in patients with COPD. We used Cochrane’s risk of bias tool for qualitative analysis. Postintervention results were quantitatively analyzed using RevMan 5.4. Results : We selected 6 RCTs of 1,039 patients with COPD performing self-management BEs. A previous systematic review and meta-analysis also included six RCTs. For pulmonary function, we found that the results of the patients performing BEs were no more effective than those of the control groups (−0.08; 95% confidence interval [CI], −0.44 to 0.27; heterogeneity, χ² = 9.73, df = 3, I2 = 69%; overall effect, Z = 0.45). However, for exercise capacity, the results of the patients performing BEs were more effective than those of the control groups (0.37; 95% CI, 0.10 to 0.64; heterogeneity, χ² = 19.54, df = 5, I2 = 74%; overall effect, Z = 2.65). Conclusion : COPD self-management BEs did not significantly affect pulmonary function, but positively affected exercise capacity.

뇌졸중 유병경험자와 정상 노인의 신체활동 강도에 따른 심혈관질환 위험요인 비교

정대인(Dae-In Jung),고대식(Dae-Sik Ko),김현중(Hyun-Joong Kim) 대한심장호흡물리치료학회 2021 대한심장호흡물리치료학회지 Vol.9 No.2

Purpose : This study aimed to analyze the difference in the cardiovascular risk factors between post-stroke elderly patients and healthy elderly patients, according to the intensity of physical activity, to determine the effect of physical activity on stroke-related cardiovascular risk factors. Methods : This study involved 4,956 elderly participants(aged >65 years) out of 24,269 subjects who participated in the 7th National Health and Nutrition Examination Survey(2016–2018). Variables that were risk factors for cardiovascular disease in the selected subjects were analyzed. Results : Total cholesterol was significantly higher in the healthy elderly group compared with the post-stroke elderly group(P < 0.05 ), and fasting blood glucose was significantly higher in the post-stroke elderly group compared with the healthy elderly group(P < 0.05 ). H DL c holesterol w as s ignificantly h igher in t he healthy e lderly group compared w ith the p ost-stroke elderly group(P < 0 .05 ). Conclusion: Comparison of the intensity of physical activity revealed the importance of blood sugar control through regular aerobic exercise and exercise intensity. It is suggested that this can serve as basic data for health promotion in stroke patients and the preventive management of cardiovascular disease in healthy elderly people.

Post COVID-19 환자들의 재활

정대인(Dae-In Jung),김현중(Hyun-Joong Kim) 대한심장호흡물리치료학회 2022 대한심장호흡물리치료학회지 Vol.10 No.1

Purpose: Data on clinical and prognosis of patients post coronavirus disease-2019 (COVID-19) and interest in rehabilitation are still insufficient. Contagious isolation causes respiratory, physical, and psychological dysfunction. Therefore, we synthesized and analyzed the effect of rehabilitation on patients with COVID-19 studied abroad. Methods: Randomized controlled trials on the rehabilitation of patients with COVID-19 were searched using four international databases: CINAHL, Embase, MEDLINE, and PEDro. For rehabilitation, a protocol including breathing training and physical activity was selected, and usual care or prior values were used for the control group. The quality of randomized controlled trials was assessed using the risk-of-bias tool provided by the Cochrane Library. Analysis was performed using RevMan 5.4, and data were weighted and pooled with a random-effects model. Results: Of the 129 studies identified, 4 were finally selected. A total of 227 patients with COVID-19 were evaluated, and significant improvements were seen in forced expiratory volume in one second (SMD = 0.75; 95% confidence interval [CI] 0.10-1.40; overall effect [Z = 2.25]) and depression (SMD = 3.46; 95% CI, 1.21-5.71; overall effect [Z = 3.02]), excluding forced vital capacity (SMD = 0.28; 95% CI −0.09 to 0.65; overall effect [Z = 1.48]). Conclusion: Rehabilitation showed improvement in respiratory function through breathing training, but a more effective protocol is required for tele-rehabilitation. In addition, interventions involving physical activity will have a beneficial effect on muscle loss and depression caused by quarantine because of coronavirus infection.