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RISS 인기검색어
- 검색키워드
- 저자 : 전석길(Seok Young Park) (검색결과 2 건)
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정상인에서 Dual-Head Gamma Camera를 이용한 위배출 연구
강영우(Young Woo Kang),손수호(Soo Ho Sohn),허정숙(Jung Sook Hur),박근용(Keun Young Park),안성훈(Sung Hoon Ahn),전석길(Seok Young Park) 대한소화기학회 1994 대한소화기학회지 Vol.26 No.2
N/A Gastric emptying study has an important role in patients with gastrointestinal functional disorders without demonstrable mechanical or mucosal abnormalities. Although several meth- ods for detection on gastrointestinal functional disorders are well known, non-invasive scintigraphic technique using a Gamma Camera is taken as a gold standard at present. A Dual-Head Gamma Camera coupled to a computer was used in 20 normal subjects after in- gestion of the mixture of ''T,-labelled scrambled egg in order to determine gastric emptying time. Four values including lag time, T,,(half gastric emptying time), remnant 1 hour, remant 2 hours were taken at all ages. In the female half gastric emptying time and lag time was slightly shorter, and the amount of remnant radioactive counts at one and two hours was smaller than the I,aale without significant difference. Delayed gastric emptying time was above 109. 9 minutes of half gastric emptying time when defined as excess of Mean+ZSD. W e believe this study using a Dual-Head Gamma Camera can be useful for establishment of more accurate gastric emptying study.(Korean J Gastroenterol 1994; 26: 2Z4 229)
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연속 양측 폐이식 실험견에서 LPDG용액을 이용한 폐보존 효과연구
김정식,권건영,유영선,전석길,박창권 啓明大學校 醫科大學 1999 계명의대학술지 Vol.18 No.1
Background: As lung transplantation has recently become successful, the shortage of suitable donor organs has become urgent problems. The current tolerable ischemic time has been accepted until 10 hours. Improvements in lung preservation would increase the number of suitable donor lungs by permitting lung harvest from longer distances, and by promoting the sharing of the two donor lungs between different centers. We prepared LPDG(low potassium dextran glucose)solution for lung preservation study. In this study we examined the efficacy of LPDG solution in 24-hour lung preservation by using of a sequential bilateral canine lung allotransplant model. Method: Seven bilateral lung transplant procedures were performed using weight-matched pairs(23 to 26 kg) of adult mongrel dogs. The donor lungs were flushed with LPDG solution and maintained hyperinflated with 100% oxygen at 10℃ for a planned ischemic time of 24 hours for the lung implanted first. After sequential bilateral lung transplantation, dogs were maintained on a ventilator for 3 hours: arterial oxygen tension, pulmonary arterial pressure, and pulmonary vascular resistance were determined in the recipients hourly after bilateral reperfusion and compared with pretransplant-recipient values, which used as controls. After 2 hours of reperfusion, the chest X-ray, computed tomogram and lung perfusion scan were performed for assessment of early graft lung function. And pathological examinations for ultrastructural findings of alveolar structure and endothelial structure of pulmonary artery were performed. Results: Five dogs of seven experiments had successfully finished the whole assessments after bilateral reperfusion for three hours. Arterial oxygen tension in the recipients was markedly decreased in immediate reperfusion period hut gradually recovered after reperfusion for three hours. The pulmonary arterial pressureand pulmonary vascular resistance showed singificant elevation (p<0.05 versus control values) but also recovered after reperfusion for three hours (p<0.05 versus immediate period value). The ultrastructural findings of alveolar structure and endothelial structure of pulmonary artery showed reversible mild injury in 24 hours of lung preservation and reperfusion. Conclusions: The present study suggests that LPDG solution provide excellent preservation and transplanted lung function after 24 hours of preservation in a canine model in which the dog is completely dependent on the fuction of transplanted lung.
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