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임의섭,최지훈 건국대학교 1991 대학원 학술논문집 Vol.34 No.-
The suspension brige consists of Cable, Deck and Tower. The load onto the deck transmitted to the cable along the hanger and, from the above process, the tensile force is generated. The generated tensile force acts as the upward load in the deck. The result of analysis of suspension bridge differs by the connected type of the cable and tower. This study was modelled the suspension bridge as a compound structure of the truss and beam, its connected type of the cable and tower is roller, and analyzed by the finite element method. The anlyzed results by this study compared to the results by the deflection theory of Melan and the finite element method of Abdel-Ghaffar.
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이원홍,임의섭 건국대학교 1992 대학원 학술논문집 Vol.35 No.-
In this paper, some methods of analysis of generally anisotropic laminated curved plates including the effects of transverse shear deformation with all edges clamped are given. When the length of the plate is great as compared with its thickness, conventional methods of structural analysis can be employed. But if the length of the plate is short compared with its thickness, no analytical solution seems to be feasible. One of the practical method of analysis of such problem is the finite difference technique. When this technique is used to solve this problem, it is desirable to reduce the order of the derivatives in order to minimize the number of the pivotal points involved in each equation. This purpose can be accomplished with relative ease. The fourth-order partial differential equation of plate bending is replaces by an equivalent three of second-order partiall differential equations with three dependant variables, namely the deflection and the slope deflections. The finite difference technique is then applied the transform these differential equations into sets of linear algebraic equations. In order to solve the resulting matrix equation with a large number of unknowns, a special scheme is used in programming for the computer. The results are obtained as follows. 1) By decreasing length-thickness ratio of plate, it is noted that the deflection values is very large difference. 2) The errors of this method considerably decrease with increasing of numbers in mesh division.
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이영란,윤주영,박춘임,안정애,임의섭,김미현,조혜경,이정아 이화여자대학교 약학회 1992 梨花藥學會誌 Vol.- No.31
Naturally occurring carcinogens of plant origin were briefly reviewed. The historical background of the studies on the bracken carcinogen and the cattle bracken poisoning and some attempts at the characterization of the active principle(s) were described. finally, ptaquiloside, an unstable glycoside of an illudane-type norsesquiterpene, was characterized as the active principle. On the basis of the chemical and biological nature of ptaquiloside, a bilogical assay method using a modified Ames' test and a chemical assay using thin-layer chromatographydensitometry were devised. By using these methods, several processed or untreated samples of the fern collected in different places, and in different seasons, were assayed for their ptaquiloside contents to show under what conditions the decompositon of ptaquiloside took place, the epidemiological meanings and whether or not they were safe as food. Wide occurrence of ptaquiloside-like compounds in the ferns of the Pteridaceae family was also revealed by the same methods and four new analogous compounds were isolated and characterized. These analogs and illudins S and M, sesquiterpenes of illudane-type from Basidiomycetes, were shown to have mutagenecity in the modified Ames' test and in chromosome abberation in CHL cells of ptaquiloside and were to be the carcinogens of the same type as ptaquiloside.
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植物의 生物活性物質探索 : 고사리의 發癌物質 The Carcinogen of Bracken Fern
이영란,윤주영,박춘임,안정애,임의섭,김미현,조혜경,이정아 이화여자대학교약학회 1992 梨花藥學硏究 Vol.- No.31
Naturally occurring carcinogens of plant origin were briefly reviewed. The historical background of the studies on the bracken carcinogen and the cattle bracken poisoning and some attempts at the characterization of the active principle(s) were described. finally, ptaquiloside, an unstable glycoside of an illudane-type norsesquiterpene, was characterized as the active principle. On the basis of the chemical and biological nature of ptaquiloside, a bilogical assay method using a modified Ames' test and a chemical assay using thin-layer chromatographydensitometry were devised. By using these methods, several processed or untreated samples of the fern collected in different places, and in different seasons, were assayed for their ptaquiloside contents to show under what conditions the decompositon of ptaquiloside took place, the epidemiological meanings and whether or not they were safe as food. Wide occurrence of ptaquiloside-like compounds in the ferns of the Pteridaceae family was also revealed by the same methods and four new analogous compounds were isolated and characterized. These analogs and illudins S and M, sesquiterpenes of illudane-type from Basidiomycetes, were shown to have mutagenecity in the modified Ames' test and in chromosome abberation in CHL cells of ptaquiloside and were to be the carcinogens of the same type as ptaquiloside.
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