당뇨환자 혈청내 Matrix metalloproteinase-3 활성도에 관한 연구

임선정,신광용,전창길,한경윤,김병옥 朝鮮大學校 口腔生物學硏究所 2000 口腔生物學硏究 Vol.24 No.2

Diabetic mellitus(D.M.) is a systemic disease commonly associated with periodontal disease. The generalized periodontal changes of D.M. are abscess formation, enlarged gingiva, loss of attachment, increased tooth mobility and loosened tooth. The loss of connective tissue attachment and bone matrix resorption in periodontal disease is mediated by matrix metalloproteinase(MMP) released by cells such as kerationocytes. fibroblasts, endothelia cells, macrophages, tumor cells and neutrophils. Increased MMP-3 activity has been recognised to be strongly associated wit hinflammatory periodontal disease. The purpose of the present study was to elucidate pathogenesis of periodonatal tissue destruction in D.M. patients through examining the activity of MMP-3 in serum. Twenty-five adults were classified into four groups : healthy control group( n=8, 23-47 years, mean age : 29.6 years ), non-periodontitis D.M. group( n=7, 35-62 years, mean age : 45.7 years ), periodontitis group( 4=4, 23-57 years, mean age : 41 years ) and periodontitis-affected D.M. group( n=6, 42-71 years, mean age : 55.5 years ). Gingival index, diabetic duration and fasting blood sugar(FBS) were examined. The activity of MMP-3 in blood serum was measured by enzyme-linked immunosorbent assay using proMMP-3 ELISA kit(The Binding site, San Diego, CA). The activity of MMP-3 was recorded by optical density measured by microwell plate reader(Bid-Tek instrument, U.S.A., 450㎚). The difference of gingival index and the optical density among groups was statistically analyzed by on way ANOVA. The relationship of diabetic duration and FBS with MMP-3 activity was statistically analyzed by Correlations. The results were as follows : 1. The diabetic duration and FBS were not associated with MMP-3 activity (p>0.05). 2. Periodontitis group was statistically higher than non-periodontitis group(p<0.05). 3. There was no significant difference in the MMP-3 activity between healthy control group and non-periodontitis D.M. group that had similar G.I.(p>0.05). 4. Periodontitis-affected D.M. group showed significantly higher activity, compared with periodontitis group that had similar G.I.(p<0.05). Within the limit of the present study, the above results suggest that periodontal inflammation is associated with increased activity of MMP-3 and periodontal destruction can be occurred more aggressively in periodntitisaffected D.M. than periodontitis alone.

Bistable photo-switching in the fluorescent photochromic polymer

임선정,안병관,박수영 한국고분자학회 2004 한국고분자학회 학술대회 연구논문 초록집 Vol.29 No.2

A Modified Strategy for the Synthesis of Hyperbranched Poly(p-phenylenevinylene)

임선정,박수영 한국고분자학회 2006 한국고분자학회 학술대회 연구논문 초록집 Vol.2006 No.4

국내 대학도서관 공간 연구의 최근 동향 분석

임선정,황미영,임채진 한국문화공간건축학회 2015 한국문화공간건축학회논문집 Vol.- No.50

University library, often called the heart of the university, performs the educational, cultural, academic and social-service functions. It should meet the informational needs of students, faculty and staff members whose academic enquiries require specialized knowledge. What needs to be pursued is a newer space that embraces the multi-cultural space for the community—the community that responds to the evolving information environment such as the development of computer and the information and communication technology. After the 2000s, while the university library in South Korea has been actively constructed and re-constructed, the strong interest has been directed to the library space that combines organically the media based on the concept of Information Commons, users, and services together to meet the changing needs of the users. In order to investigate the trends of the space study of the university library, this study analyzes the journal articles and conference proceedings published between 1981 and the end of 2014: it identifies the changing research trends by investigating the number of publications chronologically; and the publications are also classified by article keyword, research purpose, research space, research content and method. By objectively analyzing the trends of the university library space, we find that the research concern and focus have been shifting, based on the chronological characteristics, from the aspect of the arrangement or dimension to that of planning the ever-changing library space. In addition to its traditional role, we also redefine the function of the university-library space which has been evolving to serve as the social and cultural spaces for the community. The purpose of this study is to help reinventing the university library space by retracing and recasting such changes in the university library.

BUYING MERCHANDISER

임선정 한국생활과학회 2015 한국생활과학회 학술대회 Vol.2015 No.11

대학도서관 공간 분류체계와 소요공간에 관한 기초적 연구 -2000년 이후 신축·리모델링 국내 대학도서관을 중심으로-

임선정,정성욱,임채진 한국문화공간건축학회 2014 한국문화공간건축학회논문집 Vol.- No.47

At the era of knowledge and Information, the university libraries have been changing and keeping pace in this digital paradigm. So, this study investigate about the 'recently-built or newly remodelled' university libraries, and wanted to discuss about the characteristics and direction of changes in the spatial university library of the future. This study categorized the 'recent' classification system of the spacial use of the university libraries into the sector, area and unit space classification. Through the hierarchical classification, the sectors are divided into the sector of usage, sector of collection, sector for work, sector of culture & convenient facilities, and public. In case of 'sector of usage', there are three parts about adult reading area and utilizing information area, and area of academic research. Also for 'sector of collection', there are general material designations, brochures, reference designations, and electric information area. And for the sector for 'office administration' can be divided into two parts of area those are for office and administration. And for the sector for 'culture convenient facilities' can be divided into two parts of areat hose are for culture and convenient facilities. And for the last, 'public sector' are divided into space for ciculation area and ect.

대학도서관 공유공간(Commons)의 특성과 유형에 관한 연구

임선정,황미영,임채진 한국문화공간건축학회 2016 한국문화공간건축학회논문집 Vol.- No.54

Modern university libraries have been changed with the different needs of users caused by changes in social and informational environments. The libraries were only required to collect and save the information. However, over the existing roles those have been widely changed to provide opportunities to have unlimited access to the information and to make, edit, and output the information through the Internet. In addition, social and cultural places where users can do collaboration activities have been added. This study investigated an aspect of the change of university library spaces which have been changed. We formulated a system of spatial composition for modern university libraries on the basis of Donald Beagle's Information Commons. Researches include 12 domestic universities and 10 foreign universities among the universities built since 2000. We categorized the space organization of the university libraries according to the newly founded space composition system for modern university libraries. We formulated new types with the space ratio of the three Common Space(Analogue Commons, Digital Commons, Community Commons) and the floor area ratio. Furthermore, we schematized the Space Connection for each unit space of the Common Space and classified the types by graphic working according to the Quiet Level of the unit space. Conclusively, this study drew conclusions about the type and feature of the modern university libraries.

아동기 부모의 학대를 경험한 중년 여성의 삶에 대한 내러티브 탐구

임선정,정문경 한국상담학회 2020 한국상담학회 학술대회 논문집 Vol.2020 No.8

자유 곡면 형상 건축물의 패널분할과 패널링 프로세스 연구

임선정(Yim, Sun-Jung) 대한건축학회 2013 대한건축학회 학술발표대회 논문집 Vol.33 No.1

중학생의 스트레스와 심리적 안녕감 간의 관계

임선정(Im, Sun-Jeong),이수경(Lee, Soo-Kyoung) 한국웰니스학회 2018 한국웰니스학회지 Vol.13 No.2

본 연구에서는 중학생의 성별에 따라 스트레스, 심리적 안녕감, 또래관계에 차이가 있는지 알아보고, 스트레스와 심리적 안녕감 및 또래관계 간의 관계에서 또래관계가 매개효과를 보이는지 파악해 보았다. 연구대상은 중학교 1·2학년 351명의 학생이었으며, 성별에 따른 주요 변인의 차이, 변인들 간의 상관관계를 분석하고 스트레스, 심리적 안녕감, 또래관계 변인들 간의 구조적 관계를 파악하였다. 주요 연구결과는 첫째, 여학생이 외모 스트레스, 개인처지 스트레스, 의사소통, 화·소외감이 남학생보다 높은 것으로 나타났다. 둘째, 중학생의 스트레스와 심리적 안녕감 및 또래관계는 유의미한 부적 상관을 보였으며, 심리적 안녕감과 또래관계는 유의미한 정적 상관을 나타냈다. 셋째, 스트레스와 심리적 안녕감 간의 관계에서 또래관계는 부분매개효과를 보이는 것으로 확인되었다. 마지막으로 본 연구의 의의 및 한계에 관해 논의하고, 후속연구를 제언하였다. This study aims to examine the difference of gender in the aspects of stress, psychological well-being, peer relationship and the mediation effects of peer relationship on the relationship between stress and psychological well-being. The subjects in this study were 351 middle school students. Major findings were as follows. First, appearance stress, individual situation stress, communication, anger·alienation of female were greater than those of male students. Second, stress had significant negative associations with psychological well-being, peer relationship. And peer relationship had significant positive associations with psychological well-being. Third, peer relationship had partial mediation effects on the relationship between stress and psychological well-being. Finally, the implications and limitations of the study were discussed and suggested the follow-up study.