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임병도(Byeong Do Lim),이혁우(Hyuk Woo Lee),주성홍(Sung Hong Joo),정의식(Eui Sik Jung),박창서(Chang Seo Park),조성진(Sung Jin Cho) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.2
Myelodysplastic syndrome (MDS) is a relatively uncommon hematological disorder, charactedzed by cytopenia in the peripheral blood and normo-or hypercellularity in the bone marrow with morphological dysplastic change. Ineffective hematopoiesis leads to hematological failures in this syndrome. MDS is largeIy affected in older individuaIs with a median age of 60-75. It's association with pregnancy is even rarer. Although the exact incidence of MDS in pregancy is unknown, it is likely to be less than 1 per 100,000 pregnancies annually. Recently, we experienced a case of MDS presented initially during pregnancy in a 34-year-old primipara and managed with intensive hematologic support. Uerine rupture occurred in pregnancy complicated with MDS at 34 gestation weeks and a healthy infant was successfully delivered by Cesarean section. We report this case with a brief review of the literature.
신재국(Jae Kook Shin),김학준(Hag Joon Kim),임병도(Byeong Do Lim),정의식(Eu Sik Jung),박창서(Chang Sue Park),조성진(Sung Jin Cho) 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.10
Aplasic anemia is an extremely rare disease characterized by hypocellular bone marrow with fatty infiltration and peripheral blood pancytopenia. For over half of patients, no cause can be determined and the causal relation between aplastic anemia and pregnancy is not yet clear. Aplastic anemia in pregnancy is difficult to the obstetrician managing it because the risk of bleeding and infections are high and mortality in aplastic anemia associated with pregnancy is more than 20%. However, with improved treatment modalities and close clinical collaboration of hematologist and obstetrician, aplastic anemia complicated in pregnancy is becoming more frequent with favorable outcome. We experienced a case of aplastic anemia initially detected during pregnancy who was managed with intensive hematological support leading to delivery a healthy infant vaginally. We report this case with a brief review of the literature.
태아안녕검사에 있어서 Rapid Biophysical Profile 의 유용성
김학준(Hag Joon Kim),고민석(Min Seok Koh),임병도(Byeong Do Lim),여정언(Jung Eun Yeo),정의식(Eul Sik Jung) 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.6
N/A Object : The nonstress test(NST) and complete biophysical profile(BPP) were compared with the rapid biophysical profile(BPP) in order to evaluate the efficacy of the rapid BPP, namely, the combination of amniotic fluid index(AFI) and sound-provoked fetal movement(SPFM) detected by ultrasound, in predicting intrapartum fetal distress in high-risk pregnancies. Study design : From JAN 9th 2000, through JAN 5th 2001, the prospective study of diagnostic tests was conducted on a total of 91 high-risk singleton pregnancies, undergoing antepartum assessment both the standard NST and the new rapid BPP(including other indices of complete BPP). The diagnostic indices of the NST, rapid BPP and complete BPP were calculated in term of predicting intrapartum fetal distress. Result : The sensitivity, specificity, negative predictive value, and positive predictive value of NST were 50.00, 94.81, 96.05, and 42.86% respectively, and those of rapid BPP were 75.00, 98.53, 98.53, and 75.00%, and those of complete BPP were 83.33, 98.72, 98.72, and 83.33%, as well. In addition, the efficiency of NST, rapid BPP, and complete BPP were 91.57%, 97.22% and 97.62% respectively. Conclusions : The rapid BPP is an effective and reliable predictor of intrapartum fetal distress with high-risk pregnancies. Moreover, it may be inexpensive and less time-consuming method.