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      • KCI등재

        추출방법에 따른 편백 정유의 향기 성분 비교 및 아토피 개선에의 응용

        임금숙(Geum-Sook Lim),김란(Ran Kim),조훈(Hoon Cho),문영숙(Young-Sook Moon),최창남(Chang-Nam Choi) 한국생물공학회 2013 KSBB Journal Vol.28 No.2

        Volatile flavor compounds of Chamaecyparis obtuse essential oil were extracted by simultaneous steam distillation extraction (SDE) and supercritical fluid extraction (SFE) and analyzed by GC-MS. A total of 48 and 50 components were identified in essential oil by SDE and SFE, respectively. Monoterpenes, oxygenated monoterpenes, sesquiterpenes, oxygenated sesquiterpenes, and diterpenes in essential oil by SDE were 37.24, 10.9, 9.61, 0.22, and 0.22%, respectively. In the case of SFE, they were 19.1, 23.3, 22.66, 1.31, and 10.57%, respectively. Antioxidant activities were increased with the increase of essential oil up to 80 μL /mL, irrespective of extraction method. Especially, when the essential oil concentration extracted by SDE was increased from 20 to 80 μL /mL, the antioxidant activity was increased from 10.5 to 55.1%. However, over 80 μL/mL of essential oil, an equilibrium state was maintained. In the case of essential oil extracted by SFE, it was decreased compared to that of SDE. For the improvement of atopic dermatitis, various cosmetics such as an ato-cide soap, ato-cide spray, and ato-cide lotion containing essential oil extracted by SFE were tested. About over 90% was useful for the improvement of atopic dermatitis after 4 weeks of clinical trial targeting 40 female adults. These results demonstrate that ato-cide soap, ato-cide spray, and atocide lotion containing essential oil extracted by SFE could be used in functional cosmetics.

      • KCI등재

        함초 씨앗의 화학적 특성과 아질산염 소거능 및 아세틸콜린에스터레이스 저해 효과

        임금숙(Geum-Sook Lim),김란(Ran Kim),전경미(Kyung-Mi Jeon),최현숙(Hyun-Suk Choi),조훈(Hoon Cho),고하영(Ha-Young Koh),최창남(Chang-Nam Choi) 한국생물공학회 2013 KSBB Journal Vol.28 No.6

        This study was to investigate the chemical properties and nitrite scavenging and acetylcholinesterase inhibitory activities from Salicornia herbaciea seed. The lactic acid content of seed was about 2.0 fold higher than that of stem. Among various free sugars, the maximum fructose of seed, glucose of stem, and mannose contents of root were obtained, 176.3, 125.6, and 112.8 mg/100g, respectively. The maximum leucine content of seed among the essential amino acid was obtained, 853.7 mg/100g, which was about 3.0 or 6.0 folds higher than that of root or stem. In the case of glutamic acid of seed, it was 2,388.7 mg/100g , which was 5.6 or 9.8 folds higher han that of root or stem. The ratio of essential amino acid and total amino acid of seed was 30.14%. The γ-aminobutyric acid contents of seed, stem, and root were 43.87, 23.88, and 27.8 mg/100g, respectively. The catechin content of seed was an order of epigallocatechin (723.2 mg/100g) > epigallocatechingallate (654.3 mg/100g) > epicatechin (443.5 mg/100g) > gallocatechin (314.1 mg/100g). Especially, the non-gallated catechins content was about 2.0 folds higher than that of gallated catechins content. The nitrite scavenging activity of seed increased from 38.7 to 65.9% when the hot-water extract content of seed at pH 1.2 increased from 1.0 to 5.0 mg/mL. However, it was decreased to 25.7% at pH 6. The acetylcholinesterase inhibitory activity of seed was increased from 13.2 to 44.6% when the extract content increased from 20 to 100 mg/mL. These results show that S. herbaciea seed has a good potential to be used as a source of material or additive in cosmetics, food, and drug compositions.

      • KCI등재

        약물과 사회범죄

        원형섭,임금숙,원사덕,서동엽 한국병원약사회 2002 병원약사회지 Vol.19 No.4

        Because data rape drugs have disinhibiting sedative and amnesiac properties, they are being used to make sexual assault victims helpless. The drugs are usually administered to the victim in an alcoholic drink at a bar club, party, social event and so on. The drugs MDMA, Ketamine, GHB, GBL, Rohypnol, LSD, PCP, and methamphetamine are included in these categories, but it is possible for them to be used frequently in conjunction with alcohol or other drugs. Police departments often say that after ingestion of these drugs, some women have reported waking up in frat houses with no clothes on, finding themselves in unfamiliar surroundings with unfamiliar people, or having actually been sexually assaulted while under the influence of the drug. We only hope that this study may be helpful in establishing a care system for sexual assault victims and in determining of the etiology of sexual assault.

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