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신장 이식 환자와 말기 신부전 환자의 심박수 변이도 비교
김성민 ( Sung Min Kim ),최승호 ( Seung Ho Choi ),오준석 ( Joon Seok Oh ),홍택종 ( Taek Jong Hong ),신용훈 ( Yong Hun Sin ),배우형 ( Woo Hyung Bae ),김중경 ( Joong Kyung Kim ),이희룡 ( Hee Ryong Lee ),정필 ( Peel Jung ),류태현 ( T 대한내과학회 2012 대한내과학회지 Vol.83 No.5
Background/Aims: Heart rate variability (HRV) is a method for evaluation of autonomic nervous system activity by expressing the balance of sympathetic and parasympathetic tones. Some studies of HRV in patients with end-stage renal disease (ESRD) have been performed in Korea. However, few have examined kidney transplantation (KT) patients. Therefore, we investigated autonomic nervous system activity by means of HRV in patients with KT due to ESRD. Methods: We compared the pattern of cardiac sympathetic and parasympathetic activity by time- and frequency-domain analysis of HRV with 24-h Holter monitoring of 23 KT and 56 dialysis patients. Patients underwent KT between January, 2008 and June, 2011. Results: The mean ages of KT and dialysis patients were 54.2±12.3 and 53.7±12.6 years, respectively. The KT group showed increased time- and frequency-domain HRV (including HRV index), very low frequency (VLF), means and standard deviations of all normal R-R intervals for all 5-min segments of the entire recording (SDNNi), low frequency (LF), LF in normalized units (LF norm), and LF to high-frequency power ratio, compared with the dialysis group. Conclusions: Autonomic tone in patients with KT is higher than that in patients with ESRD on dialysis. (Korean J Med 2012;83:606-612)