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국민건강영양조사 자료를 통한 천식과 비만의 상관성 연구
장규진 ( Kyu Jin Chang ),구현숙 ( Hyun Sook Koo ),이현승 ( Hyeun Seung Lee ),조영아 ( Young A Jo ) 대한천식알레르기학회 2005 천식 및 알레르기 Vol.25 No.4
Background: Many studies have suggested the association between asthma and obesity both of which are important chronic health problems and socioeconomic problems. There are few studies about the association of adults in foreign nations and the association of all ages in Korea, especially based on the representative population. Objective: Authors analyze the association between asthma and indices such as BMI (body mass index), age, gender, smoking, alcohol drinking and diet habit in Korea National Health and Nutrition Survey. Method: National Survey was done from November to December 2001 and this study enrolled 27,331 men and women above 19 years of age. A structured questionnaire, weight and height were used to collect information. Obesity is defined above 25 kg/m2 of BMI. The criterion of asthma is a diagnostic history by medical doctor. Result: The overall prevalence of asthma in this study is 1.54% (male 1.50%, female 1.57%). The prevalence is higher in elderly (≥60), smokers, obese person, someone who has low educational level and does not have current partner. The significant predictors of asthma in multiple logistic regression are BMI (female OR=1.685 (95% CI=1.047∼2.713)), age (male OR=3.250 (95% CI=0.999∼10.567), female OR=6.798 (95% CI=1.583∼29.195)), educational level (male OR=5.381 (95% CI=1.857∼15.598)) and alcohol drinking (OR=0.549 (95% CI=0.323∼0.933)). Conclusion: Obesity is a risk factor of asthma in women. Old age and low educational level are social risk factors in asthma in men. (Korean J Asthma Allergy Clin Immunol 2005;25:262-268)
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적혈구 막단백 4.2 결핍에 의한 유전성 구상 적혈구증 1 예
김승호,이종우,이영석,최황,한남익,장상아,강성구,진종률,이현승,정용학,지영희 대한내과학회 1994 대한내과학회지 Vol.46 No.6
Hereditary spherocytosis is the most common form of congenital hemolytic anemia, which is characterized by spheroidal red blood cells, increased osmotic fragility and splenomegaly. The development of protein research revealed various primary defect resides in the erythrocyte membrane proteins of the spherocyte. Recently, we studied a 36-year-old male hereditary spherocytosis patient with anemia and splenomegaly, Analysis of the erythrocyte membrane proteins by SDS-PAGE showed a deficiency of protein 4.2.
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