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RISS 인기검색어
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- 저자 : 이장진 (검색결과 3 건)
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척추 전이암에서 확산강조 자기공명 영상을 이용한 치료반응의 평가
이장진,신세원 영남대학교 기초/임상의학연구소 2001 Yeungnam University Journal of Medicine Vol.18 No.1
Background: The purpose of this study was to evaluate the usefulness of diffusion-weighted magnetic resonance imaging for monitoring the response to radiation therapy in metastatic bone marrow of the spines. Materials and Methods: Twenty-one patients with metastatic bone marrow of the spines were examined with MRI. Diffusion-weighted and spin-echo MRI were performed in 10 patients before and after radiation therapy with or without systemic chemotherapy, and performed in 11 patients after radiation therapy alone. Follow up spin-echo and diffusion-weighted MRI were obtained at 1 to 6 months after radiation therapy according to patients' condition. The diffusion-weighted imaging sequence was based on reversed fast imaging with steady-state precession(PSIF). Signal intensity changes of the metastatic bone marrows before and after radiation therapy on conventional spin-echo sequence MRI and diffusion-weighted MRI were evaluated. Bone marrow contrast ratios and signal-to-noise ratios before and after radiation therapy of diffusion- weighted MRI were analyzed. Results: All metastatic bone marrow of the spinal bodies were hyperintense to normal bone marow of the spinal bodies on pretreatment diffusion-weighted MRI and positive bone marrow contrast ratios(p<0.001), and hypointense to normal spinal bodies on posttreatment diffusion-weighted MRI and negative bone marrow contrast ratios(p<0.001). The signal to noise ratios after treatment decreased comparing with those of pretreatment. Decreased signal intensity of the metastatic bone marrows on diffusion-weighted MRI began to be observed at average more than one month after the initation of the radiation therapy. Conclusion: These results suggest that diffusion-weighted MRI would be an excellent method for monitoring the response to therapy of metastatic bone marrow of the spinal bodies, however, must be investigated in a larger series of patients with longer follow up period.
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손세정 방법에 따른 세균 제거 효과 비교에 대한 융복합 연구
정무상,이장진,김지로 한국융합학회 2019 한국융합학회논문지 Vol.10 No.9
The purpose of this study is to compare the efficiency of bacteria removal of three different types of hand washing methods. This study performed a convenient sampling of 30 volunteers in cross-over design. The study divided the 30 volunteers into three random groups. The three groups were asked to use antiseptic soap, alcohol-based hand disinfectant, and disposable wet wipes respectively. The result of the study showed that mean log reduction values after each had washing method were –0.45(±0.69) with antiseptic soap and water, -1.19(±0.52) with alcohol-based hand disinfectant and –0.75(±0.58) with disposable wet wipes. The difference was statistically significant when using alcohol-based hand disinfectant compared to the other two methods (p=0.000). According to this study, alcohol-based hand disinfectant was the most effective product based on bacteria removal for hand washing. Advantages of using alcohol-based hand disinfectant are that it is cost-effective and easy to buy, also eco-friendly. Therefore, to prevent infectious disease, providing alcohol-based hand disinfectant to every corner of the community will be very helpful. 본 연구에 목적은 손세정제, 손소독제, 일회용 위생물티슈를 이용하여 손 위생용품간의 세균 제거 효과를 교차 실험설계를 통해 비교하는 융복합 연구를 진행 하였다. 연구를 위해 30명의 연구참여자를 무작위 배정하여 세 개의 군으로 나누어 총 89개의 샘플에 대한 실험을 진행하였고 세균의 증식능력을 CFU로 측정하였다. 손 위생 전 손 위생용품을 사용하였을 때의 세균 감소값은 손세정제 사용 후에서 –0.45(±0.69) log CFU/ml, 알코올 손 소독제를 이용한 경우 –1.19(±0.52) log CFU/ml, 일회용 물티슈를 이용한 경우 –0.75(±0.58) log CFU/ml 로 대조군과 비교하여 실험군에서 낮게 나타났다. 연구결과 손세정제를 사용하였을 때 사용하지 않은 경우보다 세균제거능력이 효과적인 것을 확인할 수 있었으며, 알코올 소독제 사용이 살균효과가 가장 우수한 것으로 나타났다. 그러므로 경제적이고 손쉽게 사용이 가능한 알코올 손소독제를 공공시설에 비치하는 것이 감염병을 예방에 가장 효과적일 것으로 사료된다.
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