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혈액종양 : 식도암 환자에서 발생한 항이뇨 호르몬 부적절 분비 증후군 1예
이소연 ( So Yon Rhee ),신성호 ( Sung Ho Shin ),이재혁 ( Jae Hyuk Lee ),안재성 ( Jae Sung An ),도병주 ( Byong Joo Do ),장근두 ( Geun Doo Jang ),송헌호 ( Hun Ho Song ) 대한내과학회 2015 대한내과학회지 Vol.88 No.2
Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) may be observed in various types of cancer, but is mainly seen in small-cell carcinoma. It can also be caused by several chemotherapeutic agents. However, it is a very rare phenomenon in esophageal cancer or its treatment. We report here on a case of SIADH related to esophageal cancer treatment. A 55-year-old man received chemoradiotherapy (CRT) for esophageal cancer. After receiving CRT for 5 days, he complained of nausea, dizziness, and general weakness, and his sodium level had dropped to 107 mEq/L. His volume status was clinically euvolemic and there were no edema or pigmentation. After hypertonic saline infusion, the sodium level increased and the symptoms improved. There have been several reports of SIADH associated with malignancies or chemotherapy agents. However, to the best of our knowledge, this is the first Korean case of SIADH associated with esophageal cancer that occurred after cisplatin treatment. (Korean J Med 2015;88:231-235)
알코올 남용 및 만성 간질환의 과거력이 없는 환자의 다발성 과혈관 과형성 간결절
도병주 ( Byoung Joo Do ),박인영 ( In Young Park ),이소연 ( So Yon Rhee ),송진경 ( Jin Kyung Song ),장명국 ( Myoung Kuk Jang ),조성진 ( Seong Jin Cho ),남은숙 ( Eun Sook Nam ),윤은주 ( Eun Joo Yun ) 대한소화기학회 2015 대한소화기학회지 Vol.65 No.5
Up-to-date imaging modalities such as three-dimensional dynamic contrast-enhanced CT (3D CT) and MRI may contribute to detection of hypervascular nodules in the liver. Nevertheless, distinguishing a malignancy such as hepatocellular carcinoma from benign hypervascular hyperplastic nodules (HHN) based on the radiological findings is sometimes difficult. Multiple incidental liver masses were detected via abdominal ultrasonography (US) in a 65-year-old male patient. He had no history of alcohol intake and no remarkable past medical history or relevant family history, and his physical examination results and laboratory findings were normal. 3D CT and MRI showed numerous enhanced nodules with hypervascularity during the arterial phase. After US guided liver biopsy, the pathological diagnosis was HHN. To date, several cases of HHN have been reported in patients with chronic alcoholic liver disease or cirrhosis. Herein, we report on a case of HHN in a patient with no history of alcoholic liver disease or cirrhosis. (Korean J Gastroenterol 2015;65:321-325)