태닝 오일에 의한 모낭염

이성율 ( Sung Yul Lee ),지재홍 ( Jae Hong Ji ),박하나 ( Ha Na Bak ),안성구 ( Sung Ku Ahn ) 대한피부과학회 2010 대한피부과학회지 Vol.48 No.9

Folliculitis is an inflammatory disease that has various causes. It has been widely reported to be caused by exposure to industrial oil such as cutting oil and diesel oil. A 39-year-old man presented with multiple diffuse erythematous papules with a follicular distribution on the anterior chest, back and shoulder. The histopathologic findings of the papules showed follicular epithelial destruction and a perifollicular inflammatory cellular infiltration. He was diagnosed as having folliculitis. The distribution of lesions matched with the area of tanning oil application was identical to that of the patient`s applying tanning oil before the development of skin lesions. We report here on a case of folliculitis due to applying tanning oil. Tanning oil caused the follicular occlusion and dilatation in hairless mice in one experiment. (Korean J Dermatol 2010;48(9):780~782)

한국인 건선환자에서 심·뇌혈관 질환 및 당뇨병 동반에 관한 후향적 연구

이성율 ( Sung Yul Lee ),최응호 ( Eung Ho Choi ) 대한피부과학회 2012 대한피부과학회지 Vol.50 No.8

Background: Psoriasis is now considered as a medical condition that involves not only the skin, but also the other systemic organs. According to the recent studies, psoriasis, especially, the large plaque type, is suggested as a major risk factor of cardiovascular and cerebrovascular disease. However, the prevalence of large plaque type psoriasis is relatively low, among the Asian patients, which leads to a lack of evidence in the population. Objective: This study is performed to evaluate the risk factor of cardiovascular and cerebrovascular disease in psoriasis patients. Methods: After thorough research on the past medical records of the psoriasis patients in our institute, we could classify the four types of psoriasis as guttate psoriasis, small plaque type psoriasis, large plaque type psoriasis, and palmoplantar pustulosis. We enrolled 84 psoriasis patients and 100 dermatologically healthy adults. We divided them into two groups, the psoriasis group and the control group; we compared the prevalence of cardiovascular and cerebrovascular disease between the groups. The psoriasis group was separately recorded by their types of psoriasis. We analyzed the inflammation marker and known risk factor of cardiovascular and cerebrovascular disease, such as total cholesterol, triglyceride, CRP, ESR, fasting glucose, history of diabetes mellitus and hypertension. Results: There was no noticeable difference between the types of psoriasis in all parameters. However, there were statistically significant differences between the psoriasis group and the control group in the parameters of ESR, CRP and prevalence of hypertension and diabetes mellitus. Conclusion: There was no difference in medical co-morbidities and their risk factors between the groups. However, in the psoriasis group, the prevalence of hypertension and diabetes mellitus, which count as the risk factors of cardiovascular and cerebrovascular disease, were higher than the normal control group. Therefore, we suggest that the psoriasis should be considered as a risk factor for cardiovascular and cerebrovascular disease in Korea.

경구 스테로이드와 국소 Tacrolimus에 의해 부분적인 호전을 보인 전두부 섬유성 탈모증

이성율 ( Sung Yul Lee ),김재홍 ( Jae Hong Kim ),지재홍 ( Jae Hong Ji ),이원수 ( Won Soo Lee ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.5

Frontal fibrosing alopecia (FFA) is a rare subtype of cicatricial alopecia. It was first described in 1994 by Kossard as postmenopausal frontal fibrosing alopecia. Patients who suffer from FFA show typical frontal hairline recession, and most patients experience eyebrow loss. It usually affects mainly post-menopausal women but the hormonal change due to menopause is unclear. Etiology of FFA is not clear, but it is assumed that certain autoantigens in the frontal and eyebrow hair follicles play a key role in its pathogenesis. There is no optimal treatment thus far. However, recently, topical calcineurin inhibitor was shown to be effective in early stage FFA via follicular targeted T-cell inhibition. Here, we report a case of a premenopausal 50-year-old female patient suffering from FFA displaying typical clinical features and minimal fibrosis around follicles by histological examination, which were improved by treatment with short-term systemic steroid and long-term topical calcineurin inhibitor. (Korean J Dermatol 2011;49(5):436∼439)

손발을 침범한 비전형장미색비강진

이성율 ( Sung Yul Lee ),김재홍 ( Jae Hong Kim ),지재홍 ( Jae Hong Ji ),이원수 ( Won Soo Lee ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.3

Pityriasis rosea, first described by Gilbert in 1860, is a fairly common dermatosis. The exact cause of pityriasis rosea is not known. The earliest clinical finding of a typical case is a herald patch, which is usually on the trunk, and scaly and erythematous daughter macules, which is distributed along the skin cleavage line, such as the ``Christmas tree pattern``. This may be accompanied by Itching. Atypical cases of pityriasis rosea, such as palmoplantar, unilateral, vesicular and inverse forms, have also been reported. There is no difference between typical and atypical cases regarding the presence of a herald patch and/or symptoms. Differences between typical and atypical cases lie in the distribution of skin lesions and the characteristics of daughter macules. Hands and feet, including palms and soles, are rarely involved in pityriasis rosea. Moreover, there are no reported pathologic findings of pityriasis rosea of the palms and soles, even in atypical distributed pityriasis rosea case reports. Here, we report atypical case of pityriasis rosea with palmoplantar involvement with pathologic reports. (Korean J Dermatol 2011;49(3):279∼282)

알레르기접촉피부염 환자(영서지역, 2005~2010년)의 첩포검사(TRUE Test) 결과에 관한 고찰

설근동 ( Geun Dong Sul ),이성율 ( Sung Yul Lee ),김재홍 ( Jae Hong Kim ),홍한나 ( Han Nah Hong ),천재순 ( Jae Sun Chun ),안성구 ( Sung Ku Ahn ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.7

Background: Since 2005, the commercial patch test panel, the TRUE-test, has been available. However, there have been no reports regarding the results of the TRUE-test compared with previously used Korean Standard Series in Korea. Objective: This study aimed to evaluate the prevalence of the contact allergy, causative allergens, and source of allergens in patients who were diagnosed with allergic contact dermatitis, and to compare the findings with previously used Korean Standard Series. Methods: We reviewed the results of the TRUE-test from 2005~2010 in Wonju Christian Hospital. We patch-tested 843 patients who were diagnosed with allergic contact dermatitis. The patch test reading was performed on day 2 and days 3 or 4, according to the patients` needs. Epidemiologic findings of patients and the results of the patch tests were analyzed. Results: A total of 843 patch-tested cases were compiled and analyzed. Of 843 patch-tested patients (male, 309; female, 534), 65.8% had at least 1 positive reaction and 30.2% at least 2 positive reactions. The highest age distribution was the 5th decade in females. The face, with the exception of the eyelids, ears, and lips, was the most frequently affected site (comprising 50.3%). The highest sensitization rates were found with nickel (29.1%), thiomersal (10.9%), and cobalt dichloride (9.7%). The lowest positivity included caine mix (0.7%), mercaptobenzothiazole (1.2%), and quinolone mix (1.2%). Metal allergens displayed higher positive rates than any other standard allergens. The overall prevalence was similar with a recent report in Korea. Conclusion: There was no significant difference in the overall prevalence of the most sensitized allergen compared with the reports about previously used Korean standard series.

피부 콜레스테롤 색전증

홍한나 ( Han Nah Hong ),이성율 ( Sung Yul Lee ),전수영 ( Soo Young Jeon ),박하나 ( Ha Na Bak ),안성구 ( Sung Ku Ahn ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.8

A cholesterol embolism is a systemic disease resulting from the occlusion of arteries by cholesterol crystals released from atheromatous plaques. It has been associated with inflammation, sheering forces from blood flow due to hypertension, aneurysm formation, infection, mechanical manipulation during surgery or vascular procedures, and anticoagulation. We report a case of a cutaneous cholesterol embolism in a 66-year old man who had purpuric skin lesions on both feet associated with diabetes mellitus, hypertension, and anticoagulation for a cerebral infarction. (Korean J Dermatol 2011;49(8):762∼764)

후경부에 발생한 부이주

지재홍 ( Jae Hong Ji ),오윤석 ( Yoon Seok Oh ),김재홍 ( Jae Hong Kim ),이성율 ( Sung Yul Lee ),박하나 ( Ha Na Bak ),이상훈 ( Sang Hoon Lee ),안성구 ( Sung Ku Ahn ) 대한피부과학회 2009 대한피부과학회지 Vol.47 No.7

Cervical accessory tragus is a rare congenital malformation presenting at birth as a firm nodule on the neck along the anterior edge of the sternocleidomastoid muscle. It has also been reported under different names, such as elastic cartilage choristoma of the neck, Meckel`s cartilaginous remnant, cervical tab, cervical auricle, and wattle. Histologically, cervical accessory tragus is composed of numerous hair follicles, and a prominent connective tissue framework in the subcutaneous fat and central core of cartilage. We report a case of an 8-year-old female who presented with a solitary flesh colored papule on the posterior neck that was histopathologically diagnosed as cervical accessory tragus. (Korean J Dermatol 2009;47(7):838~840)

금침 시술 후에 발생한 가성림프종 1예

지재홍 ( Jae Hong Ji ),박화영 ( Hwa Young Park ),이윤희 ( Yoon Hee Lee ),이성율 ( Sung Yul Lee ),홍승필 ( Seung Phil Hong ),안성구 ( Sung Ku Ahn ) 大韓皮膚科學會 2009 大韓皮膚科學會誌 Vol.47 No.9

Cutaneous pseudolymphoma refers to a heterogeneous group of benign reactive T- or B-cell lymphoproliferative diseases of the skin that resembles cutaneous lymphoma both clinically and histologically. Although most pseudolymphomas develop from unknown causes, various stimuli can induce pseudolymphomas. Pseudolymphomas have developed followed medications, infections, insect bites, ear piercing, and gold. To date, no case of pseudolymphoma developing after gold acupuncture has been reported in the Korean dermatologic literature. We report a case of a 49-year-old female who presented with multiple skin-colored papules on the left lower eyelid that showed features of a pseudolymphoma based on histopathologic assessment. (Korean J Dermatol 2009;47(9):1083∼1086)

유충 피부유주증 1예

김재홍 ( Jae Hong Kim ),지재홍 ( Jae Hong Ji ),이성율 ( Sung Yul Lee ),최응호 ( Eung Ho Choi ) 대한피부과학회 2010 大韓皮膚科學會誌 Vol.48 No.3

Cutaneous larva migrans (CLM) is an uncommon cutaneous creeping eruption caused by the invasion and migration of nematode larvae into the skin. Burrowing larvae produce intensely pruritic, serpiginous, raised erythematous skin lesions. Most cases of CLM reported in Korea involved travelers returning from endemic areas with tropical or subtropical climates. We report herein a case of CLM with no history of travelling to endemic area and briefly review the relevant literature. (Korean J Dermatol 2010;48(3):250~252)