국내에 분포하는 Sordariales 목 균에 관한 보고

이선주,류진창,고승주 ( Seonju Lee,Jin Chang Ryu,Seung Joo Go ) 한국균학회 1998 韓國菌學會誌 Vol.26 No.3

요엽후박나무 추출물의 입술 주름 개선에 대한 연구

이선주 ( Seonju Lee ),김미나 ( Mina Kim ),박성범 ( Sung Bum Park ),김기영 ( Ki Young Kim ),박선규 ( Sun-gyoo Park ),김미선 ( Mi-sun Kim ),강내규 ( Nae-gyu Kang ) 대한화장품학회 2019 대한화장품학회지 Vol.45 No.1

입술은 각질층이 매우 얇아 수분증발에 취약하며, 노화 과정에서 주름이 증가하고, 붉은색을 잃으며, 볼륨이 감소하게 된다. 매력적인 입술을 가지기 위해 시행되는 지방이식, 필러 주입을 대체하기 위한 성분에 대한 연구는 아직 보고된 바가 거의 없으며, 최근 새로운 지방세포의 수를 증가시키는 것이 인체 내 지방을 늘릴 수 있는 방법으로 제안되고 있다. 우리는 선행연구에서 지방줄기세포를 지방세포로 분화 유도하는 천연물질로써 요엽후박나무 추출물(Magnolia officinalis bark extract)의 우수한 효능을 확인하였다. 본 연구에서는 요엽후박나무 추출물이 바이오 프린팅으로 제작한 지방 유사 구조체에서 지방(lipid droplet)의 양을 증가시키면서 분화를 촉진시킴을 3D 수준에서 확인하였다. 다음으로 입술 주름에 미치는 영향을 확인하기 위해 주름 사진으로 부터 명암값의 표준편차(SDGV)를 J 이미지 소프트 웨어를 사용하여 측정함으로써 객관적 측정 방법을 확립하였고, 주름 정도에 따른 입술 주름 그레이드를 도출하여 정량화하였다. 결과적으로 요엽후박나무 추출물 1%를 함유한 제품을 12주간 사용했을 때, 입술 주름을 유의하게 개선시킬 수 있음을 확인하였다. 본 연구 결과는 요엽후박나무 추출물이 지방줄기세포를 지방세포로 분화 유도하는 효능을 가지며, 이러한 효능이 입술 주름을 개선하는데 도움을 줄 수 있다는 점을 시사하고, 따라서 요엽후박나무 추출물은 입술 주름과 볼륨을 개선하는 화장품 후보 소재로 적용 가능하다는 것을 보여준다. Lips have a defect in maintenance of moisture due to their thin layer. As aging progresses, lips lose volume and redness, and become wrinkled. Fat grafting and filler surgery have been used to achieve attractive lips, but little research has been reported to develop better materials to replace the present methods. Recently, a study suggests that the increase of adipocyte number can be enhancing the expansion endogenous fat. In previous study, we identified that the efficacy of Magnolia officinalis bark extract (MOBE) was effective on the induction of adipogenic differentiation. In this study, we confirmed that MOBE enhanced the differentiation of human adipose-derived stem cells on the fat mimic 3D structure built by 3D bioprinting method From further experiments in human, we established a method to quantify the severity of lip wrinkle by measurement of standard deviation of gray value using Image J software. Finally, we found that topical treatment with 1% MOBE formulated lip balm significantly improved the lip wrinkle after using for 12 weeks. In conclusion, these findings suggest that MOBE has great potential, as a cosmetic ingredient, to reduce the lip wrinkle through the effect of promoting adipogenic differentiation.

신재생산기술에 대한 페미니즘의 논쟁과 여성의 위치

이선주(Seonju Lee) 한국동서비교문학학회 2016 동서 비교문학저널 Vol.0 No.36

To analyze the feminist debates on new reproductive technology, this study applies the two perspectives of technological determinism and one that transcends it. In the perspective of technological determinism, we examine radical feminism and eco-feminism which opposes new reproductive technology and cyber feminism which praises the technology. We call the perspective which separates technology from society to regard it as an independent area and perceives an inherent characteristic within the technology itself as technological determinism. Not only are radical feminism and eco-feminism which regard new reproductive technology as a vice classified as technical determinism but cyber-feminism which praises technology as being beneficial to women also belongs to it. The position of technological determinism regards the female as being extremely passive. The female is not given any autonomous agency as she is positioned as the victim of patriarchal capitalism or the subject of new reproductive technology experiments. In the stance opposing technological determinism, the various locations and agency of the female is emphasized. Sawicki of the Foucalt Feminism who examines the location of female resistance while objecting to new reproductive technology belongs to this position. Also, Haraway, who finds the potential for female liberation through post-human technology and cyborg, asserts the theory connecting the ‘situated knowledge’ of women who are placed in different positions and situations with female agency. This study examines how Sawicki and Haraway, while holding contrasting positions to technology, both transcend technological determinism to thereby actively interpret the location and agency of females.

디킨즈의 『돔비부자』- 근대경제와 성(Sexuality)

이선주(Seonju Lee) 19세기영어권문학회 2008 19세기 영어권 문학 Vol.12 No.2

The title Dombey and Son has two meanings, both the patriarchy home and family business. This novel focuses on the connection between modern economy and sexual economy. This novel portrays the transition from the age of chariot to the age of railway in the 1840s’ railway building boom. If the transitional age of spirit can be expressed by the transportation, it also appears through the national economy policies from the monopolistic mercantilism to the free trade system. The conflicts and catastrophe are caused by the coercive situation where the law of command and control and profit-orientated mind in business world are directly adapted to the law of family management. This paper explores first Dombey’s modern economic character and then the relation of modern economy and sexuality. The last chapter examines the novel’s dual direction of desires in which the one desire is to reveal the sexuality and the other desire is to bury the sexuality and examines how these contradictory movements bring up the ending’s dramatic turning. The connection between modern economy and sexuality economy is evident in Dombey who recognizes the personal and emotional marital relation only through the econmic level. To him Edith Dombey is a bought woman. Edith’s self-disgust turns into a loathing for Dombey and she becomes attached to Florence. Her focus upon Florence is an interesting combination of physically intense female-female erotics and passionate fetishization of Florence’s innocence. This novel shows also sexual deviation through Carker’s homosexual nuance. This book has the two contradictory narrative directions where the early movement is to reveal and posit the sexual desire in a foreground and the later movement is to get rid of the dangerous sex and bury the sexual desire. As Edith cannot disrupt the coherency of the narrative’s representations of power, the narrative direction is the recovery of normalcy, that is the recovery of male power on every front of public and private life.

포스트휴먼 관점에서 본 『프랑켄슈타인』

이선주(Seonju Lee) 19세기영어권문학회 2017 19세기 영어권 문학 Vol.21 No.1

The reason why I look at Frankenstein from a posthuman perspective is that the monster in the novel is not an animal-like human being but an artificial life made by technology. The scientific experiment that Frankenstein tried to create was successful, different from his expectation. The monster is not only surprising for the outset of the 19<SUP>th</SUP> century when the novel was first published, but also surprising even in the situation of contemporary times in which artificial life has developed. The monster has been actually produced as an artificial human transgressing the boundaries between the human and non-human, the organic and machine. Chapter 2 examines that the modern science represented by Frankenstein is based on mechanistic theory. The process of making a human out of inorganic material such as the limbs of a dead body by applying artificial material such as electricity is based on the mechanistic theory of modern science. I analyze that Frankenstein’s action of discarding the artificial human at the moment of his creation due to the monstrous appearance is based on the Cartesian mechanistic theory. Chapter 3 investigates that the narrative in which the monster forms a consciousness through his senses coincides with the concept of sense and consciousness from the posthuman perspective. Consciousness is not unique to the human nor produced from a specific area of the brain. Chapter 4 focuses on the narrative of Frankenstein, recording the emergence of the artificial life, thus showing the attributes of mechanistic text. I try to analyze that from the mid-section in which the monster starts up a whirlwind by subsuming the control of the text to himself. I emphasize how the resolute action that Frankenstein demonstrates when he loses all against the monster can be considered as Gilles Deleuz’s ‘Becoming,’ that is, ‘becoming monster.’

아담 스미스의 『도덕감정론』 과의 연관 속에서 찰스 디킨스의 『돔비 부자』 읽기

이선주(Seonju Lee) 19세기영어권문학회 2015 19세기 영어권 문학 Vol.19 No.1

The study compares Charles Dicken`s Dombey and Son (1848) with Adam Smith`s studies in the perspective of modern knowledge as there are great similarities between their thoughts and concepts. Smith understood that his age was a period of transition into the modern society in which one can break free from medieval class order and attempt at self-development through autonomous economic activities based on self-love. Smith`s The Wealth of Nations deals with the challenging commerce society of the Modern Britain, while The Theory of Moral Sentiments proposes an alternative to correct capitalist society in which each person performs economic activities based on self-love. Smith tried to solve the problem by perceiving the world as a binary structure in which on one part, he diagnosed the economic reality of his age and on the other, he presented a correction rod so that the economism may not overly become rampant. The broad framework of a binary structure towards modernity that has started from the great theorist Smith has continued onto Dickens. While Smith proposed the binary structure of the economic problems of modern commercial society and moral sentiment for keeping social order through two books, Dickens presents such binary structure in one novel, forming the broad frame of the novel. This study analyzes Dicken`s novel in relation to Smith`s The Theory of Moral Sentiments. Smith emphasized that in order for and justice to be maintained in a society in which every agent strives for self-development based on self-love, propriety must be kept through the moral sentiment of sympathy. The theory of sympathy that is central in Smith`s is very effective in analyzing the conflict or deviation of sympathy that is given significant weight in Dombey and Son. First, the non-existence of sympathy between the central characters and the causes and effects of sympathy conflict is analyzed in relation to Smith`s The Theory of Moral Sentiments. Second, Smith calls the tendency in which people who have realized wealth and power to easily receive sympathy from others as deception and indicates that it is this deception that brings about the development of modern market economy. How Dickens is similar to and differs from Smith`s position of economic liberalism is analyzed. Third, Dickens`s moral judgment on central characters I ending can be likened to the judgment of what Smith deems as the `impartial spectator,` and Dickens`s tendencies presented through this judgment will be analyzed.

연생모형을 이용한 역모기지의 분석

백혜연,이선주,이항석,Baek, HyeYoun,Lee, SeonJu,Lee, Hangsuck 한국통계학회 2013 응용통계연구 Vol.26 No.3

연생모형(multiple life model)은 보험계약에서 두 명 또는 그 이상의 피보험자들의 사망 또는 생존의 상태에 따른 보험금을 지급하는 보험 상품의 보험료 결정 및 리스크 관리를 위한 모형이다. 본 논문에서는 부부 가입자 중 마지막 사망자가 발생할 때까지 연금이 지급되는 연생보험의 대표적인 상품인 역모기지를 살펴보고자 한다. 역모기지 상품은 만 60세 이상의 고령자가 소유주택을 담보로 거주하면서 일정액을 대출받지만 대출금을 다시 상환하지 않는 금융상품으로 부부 가입의 경우 대출 기간의 확률분포를 적용하기 위해서는 연생모형을 적용해야만 한다. 그러나 현행 역모기지 상품에 있어서 대출한도 및 월지급금 산출 시 연생모형이 적용되지 않고 있으며 우리나라의 경우에는 국민 생명표 상의 여자 사망률을 대출 종료(연금지급종료)확률로 활용하고 있다. 여자의 사망률을 이용하는 이유는 보수적인 관점에서 대출 종료 시점을 예측하기 위해 일반적으로 남자보다 여자가 더 수명이 길다는 점 때문이다. 고령화로 인해 수명이 점점 길어지는 추세이기 때문에 역모기지와 같이 계약기간이 확정되어 있지 않은 보험 상품의 경우 특히 더 계약 종료 시점에 대한 확률분포가 리스크 관리를 위하여 중요하다. 본 논문의 의의는 역모기지의 발행기관 및 보증기관의 적정한 월지급금 지급과 차후 월지급금의 과대지급으로 인한 지급불능을 방지하기 위해 현행 사용하고 있는 모형의 위험률에서 연생 모형으로 변경할 필요성을 실증분석을 통하여 제시한다. Multiple life models are useful in multiple life insurance and multiple life annuities when the payment times of benets in these insurance products are contingent on the future life times of at least two people. A reverse mortgage is an annuity whose monthly payments terminate at the death time of the last survivor; however, actuaries have used female life table to calculate monthly payments of a reverse mortgage. This approach may overestimate monthly payments. This paper suggests a last-survivor life table rather than a female life table to avoid the overestimation of monthly payments. Next, this paper derives the distribution of the future life time of last survivor, and calculates the expected life times of male, female and last survivor. This paper calculates principal limits and monthly payments in cases of male life table, female life table and last-survivor life table, respectively. Some numerical examples are discussed.

Ulrich Manthe․Shigeo Nishimura․Mariko Igimi(공동편집), Aus der Werkstatt römischer Juristen: Vorträge der Europäisch-Ostasiatischen Tagung 2013 in Fukuoka (Duncker & Humblot, Berlin, 2016년, 515면)

서을오(Seo, Eulo),이선주(Lee, Seonju),이상훈(Lee, Sang Hoon),한승수(Han, Seungsoo) 한국법사학회 2017 法史學硏究 Vol.55 No.-

포항지역에서 발생한 무균성 뇌막염 환아의 역학적 양상 연구 : 1997~2002

김석헌,배순호,정해관,정철,이선주,고준태,김문규,정은영,Kim, Seog Heon,Cheong, Hae-Kwan,Jung, Cheoll,Lee, Seonju,Ko, Joon Tae,Kim, Moon Kyu,Jeoung, Eun Young,Bae, Sun Ho 대한소아감염학회 2003 Pediatric Infection and Vaccine Vol.10 No.2

목 적 : 1997년부터 2002년까지 6년 동안 포항지역에서 발생한 무균성 뇌막염의 역학적 양상을 연도별로 비교하고 누적발생률을 확인하여 추후 무균성 뇌막염의 전파양상 규명과 예방에 기초자료를 제공하기 위해 본 연구를 시행하였다. 방 법 : 1997년부터 2002년까지 포항지역 3개 종합병원에 무균성 뇌막염으로 1일 이상 입원한 15세미만 환아 중 소아과 전문의와 전공의의 의무기록지 검토를 통해 확인된 1,750명을 대상으로 역학적 발생양상을 조사하고, 누적발생률을 산출하였다. 결 과 : 전산기록으로 확인한 환아의 95.2%(1,750명 : 남아 1,078명, 여아 672명)를 무균성 뇌막염으로 확인하였다. 6개년도 모두 남아가 여아보다 많았으며(1.6 : 1), 1997년에 464명이 발생한 이후 발생수가 감소하였다가 2000년 이후 다시 증가하여 2002년 648명으로 가장 많이 발생하였다. 발생월별 분포는 6월이 31.3%로 가장 많았으며, 5월부터 8월까지 4개월간 집중적으로 발생하여 전체 발생의 84.2%를 차지하였다. 증상 발현일부터 입원까지 걸린 기간은 0일에서 35일까지 다양하였으며, 평균 $4.19{\pm}2.96$(중앙값 3일)일이 소요되었다. 5일 이내가 1,417명(81.0%)을 차지하였다. 증상발현 당일 입원한 경우는 3명(0.2%)에 불과하여 증상이 진행된 후에 병원을 방문하는 것으로 확인되었다. 환아의 연령을 3단계로 구분하여 각 연도별로 인구 10만명당 누적발생률을 조사한 결과 각 연도마다 다발 연령군이 상이한 결과를 보였으며, 매년 특정 연령군 대에 환아가 집중하지 않는 것으로 확인되었다. 결 론 : 1997년부터 2002년까지 포항지역 3개 종합병원에서 입원 치료받은 무균성 뇌막염 환아의 역학적 양상을 조사하였다. 포항지역의 무균성 뇌막염 환아가 매년 지속적으로 보고되고 있으므로 원인을 규명하고 장기적인 예방대책을 수립하기 위한 연구가 계속되어야 할 것이다. Purpose : This study was performed to investigate the epidemiologic feature of aseptic meningitis in Pohang city for 6 years from 1997 to 2002. Methods : We reviewed the clinical records of 1,839(1,138 male and 701 female) aseptic meningitis patients who had been admitted to 3 general hospitals in Pohang city from 1997 to 2002. Results : 1,750 cases(1,078 male and 672 female) were selected as aseptic meningitis by reviewing clinical records. The ratio of male to female was 1.6 : 1. Aseptic meningitis occured in children of all age groups, and the prevalent age group was different by year. The most common developed month was June(31.3%), and 84.2% of cases were focused from May to August. The time from the initial manifestation to hospital admission was $4.19{\pm}2.96$ (median 3 days). Conclusion : We were performed to investigate the epidemiologic feature of clinical records of Aseptic meningitis pediatric patients who had been admitted and treated to 3 General hospitals in Pohang city from 1997 to 2002. We have to keep up Our study for consideration of the basic of Aseptic meningitis epidemiology and long term control is necessary to prevention the impact of Aseptic meningitis because Aseptic meningitis pediatric patients were continuously recorded by Epidemiological annual report in Pohang city.

천리안해양위성 연속자료 구축을 위한 GOCI-II 임무 초기 주요 해색산출물의 GOCI 자료와 비교 분석

박명숙 ( Myung-sook Park ),정한철 ( Hahn Chul Jung ),이선주 ( Seonju Lee ),안재현 ( Jae-hyun Ahn ),배수정 ( Sujung Bae ),최종국 ( Jong-kuk Choi ) 대한원격탐사학회 2021 大韓遠隔探査學會誌 Vol.37 No.5

최근 GOCI-II 위성이 발사되면서 우리나라는 세계 최초로 약 20년 동안 정지궤도상에 있는 천리안 해양위성 시리즈(GOCI, GOCI-II)를 운용하게 되었다. 본 연구에서는 GOCI-II 주요 해색산출물인 엽록소-a 농도(Chl-a), 유색용존유기물(CDOM), 원격반사도(R_rs)를 GOCI 자료와 비교 분석하여, 위성 임무초기 산출물의 현황을 파악하고 향후 천리안 해양위성 시리즈 데이터 구축을 위한 알고리즘 개선 방향을 논의한다. 2020년 황해, 남해, 울릉분지에서 GOCI-II의 엽록소-a 농도의 공간적인 분포는 GOCI 뿐 아니라 MODIS와도 잘 일치한다(상관계수: 0.83 이상). 특히, 여름철 울릉 분지 영역에서는GOCI와GOCI-II 자료의 엽록소-a 농도는 RMSE도 낮으며(~0.08), 편향성(Systematic Bias)도 거의 없었다. 선택된 모든 영역에서 490 nm와 555 nm 원격반사도는 GOCI와 GOCI-II 간 불확도가 낮고, 유사한 경향성이 나타났다. 그러나, 남해와 황해의 443 nm 원격반사도의 경우 GOCI-II가 GOCI에 비해 과소추정하여, 엽록소-a 농도와 유색용존유기물의 과다추정을 유도한다. 또한, 660 nm 원격반사도의 경우에도 systematic bias가 나타나 총부유입자 산출물에 영향을 줄 수 있다. 본 연구는 현재 GOCI-II 자료는 기본적으로 GOCI나 MODIS와 잘 일치하고 있어, 해양환경 관측을 위한 기본적인 신뢰도는 확보되었음을 의미한다. 그러나, 향후 GOCI-II 복사보정, 산출물 검보정, 알고리즘 개선으로 자료의 정량적인 정확도를 개선하는 연구가 반드시 필요하며, 이를 기반으로 20년간 천리안 해양위성자료의 일괄적 재처리로 GOCI, GOCI-II 연속성이 보장된 자료를 제공할 수 있다. The recent launch of the GOCI-II enables South Korea to have the world’s first capability in deriving the ocean color data at geostationary satellite orbit for about 20 years. It is necessary to develop a consistent long-term ocean color time-series spanning GOCI to GOCI-II mission and improve the accuracy through validation using in situ data. To assess the GOCI-II’s early mission performance, the objective of this study is to compare the GOCI-II Chlorophyll-a concentration (Chl-a), Colored Dissolved Organic Matter (CDOM), and remote sensing reflectances (R_rs) through comparison with the GOCI data. Overall, the distribution of GOCI-II Chl-a corresponds with that of the GOCI over the Yellow Sea, Korea Strait, and the Ulleung Basin. In particular, a smaller RMSE value (0.07) between GOCI and GOCI-II over the summer Ulleung Basin confirms the GOCI-II data’s reliability. However, despite the excellent correlation, the GOCI-II tends to overestimate Chl-a than the GOCI over the Yellow Sea and Korea Strait. The similar over-estimation bias of the GOCI-II is also notable in CDOM. Whereas no significant bias or error is found for R_rs at 490 nm and 550 nm (RMSE~0), the underestimation of R_rs at 443 nm contributes to the overestimation of GOCI-II Chl-a and CDOM over the Yellow Sea and the Korea Strait. Also, we show over-estimation of GOCI-II R_rs at 660 nm relative to GOCI to cause a possible bias in Total suspended sediment. In conclusion, this study confirms the initial reliability of the GOCI-II ocean color products, and upcoming update of GOCI-II radiometric calibration will lessen the inconsistency between GOCI and GOCI-II ocean color products.