정상임신 및 비임신부에서의 성염색질 출현 빈도에 관하여

이경희(KH Lee) 대한산부인과학회 1973 Obstetrics & Gynecology Science Vol.16 No.7

정상임신 및 비임신부에서의 성염색질 출현 빈도에 관한 연구에서 비임신부와 임신부간에는 통계적으로 유의한 차를 확인할 수 없었다. Sex chromatin mass in the interphase nuclie of somatic cells has proven to be a diagnostic value as an indication of the number of X chromosomes. Recently several investigators reported changes in sex chromatin frequency of mucosal cells throughout the pregnancy and the menstrual cycle. To observe any significant change in the frequency of sex chromatin positive cells with relation to menstrual cycle and pregnancy, 141 pregnant and 176 non-pregnant women have been subjected for the sex chromatin count using carbolfuchsin staining of the oral mucosal cells. Results: 1. The mean sex chromatin frequency was 32.6 per cent in women with normal menstrual cycles. 2. No significant changes in the sex chromatin frequency has been observed in relation to the menstual cycle. 3. The mean sex chromatin frequency was 33.7 per cent in pregnant women. 4. Statistical analysis revealed no significant differnce in the mean sex chromatin frequency among each trimester groups. 5. No significant difference has been observed in the mean sex chromatin frequency between pregnant and non-pregnant condition.

정상부인의 난관에 대한 세포학적 및 조직학적 연구

이경희(KH Lee),김승욱(SW Kim) 대한산부인과학회 1981 Obstetrics & Gynecology Science Vol.24 No.2

Recent report have suggested that intrauterine device(IUD) users may have an increased likelihood of deloping salpingitis. In order to set a basis for comparison with those women wearing IUD, a study on the bacteriology and histology was performed with fallopian tubes obtained at the time of tubal ligation from 40 normal healthy women who have not used IUDs. The results obtained are summarized as follows. 1. The rate of bacteriological contamination of fallopian tube was 17.5% in normal women. 2. Microorganisms cultured from the fallopian tube of normal women were Staphylococcuus, Eubacterium , Bacterodies, Streptococcus, etc. Inclding Lactobacillus. 3. Twenty-eight percent of women were found to have histological evidence of salpingitis. 4. There seems to be no correlation between the positive bacterial culture of the fallopian tube and the histological evidence of salpintitis.

여성외음부에 발생한 Paraffinoma

이경희(KH Lee),최태일(TI choe),황상의(SU Hwang),조진희(CH Cho) 대한산부인과학회 1970 Obstetrics & Gynecology Science Vol.13 No.10

The paraffinoma is a kind of granuloma, revealing the pattern of chronic inflammation and giant cell reaction, developing after the injection of paraffin oil in the tissue. Two cases of the paraffinoma on the female external genitalia were presented, and the literatures of paraffinomas are briefly reviewed.

Methylcyanoacrylate를 이용한 여성 불임수술

이경희(KH Lee),장윤석(YS Chang) 대한산부인과학회 1984 Obstetrics & Gynecology Science Vol.27 No.12

A simple, effective, non-surgical female sterilization procedure that can be applied on an outpatient basis would be of potential benefit in family-planning programs. We have undertaken a clinical trial of MCA in 30 cases of ambullatory women who wished to be sterilized. MCA is a tissue adhesive which can be delivered transcervically to the fallopian tubes by means of the FEMCEPT-MCA device. In our trial of ambullatory patients treated with the FEMCEPT-MCA system, 1. the bilateral tubal closure rate was 80%(24 bilateral tubal closure among 30 women) in the first application. 2. there have been no significant complications or side effects. 3. there were 2 cases of pregnancies among 24 women who had proven bilateral tubal closure one was intrauterine pregnancy after 13 months and the other was ectopic pregnancy after 17 months. The FEMCEPT-MCA system requires minimal technical skills for its application and appears to be readily adaptable to mass production and distribution. It holds promise as a new method for permanent female contraception. Its wide spread use will depend upon achieving a high closure rate in a large series of patients.

과대아의 임상통계적 관찰

이경희(KH Lee),손순희(SH Sohn),강병필(BP Kang),유명렬(MY Yoo) 대한산부인과학회 1969 Obstetrics & Gynecology Science Vol.12 No.8

Deliveruy of giant baby is one of the most important subjects in Obst. & Gynec. field, since this brings quite often dystocia and other dangerous complication. Many have been reported on the delivery of giant baby with varying definitions. According to these weight of the newborn infant depends onvarious factors such as origin, climate, season, sex, gestation period, age and health of the mother, number of deliveries, state of nutrition during pregnancy, social and eco-nomical situation around parents. Among a total of 8962 new born infants in our hospital during the period from Jan. 1964 to Aug. 1968, we have conducted a series of clinical observation against 533 infants weigging more than 4.000g. Our observation and study is summaried as below; 1. Frequency of delivery of the giant baby is independent on the season of delivery. 2. More giant babies are born by multipara than primipara. 3. Giant babyis more closely associated with multipara or grandpara and extended gestation period. 4. Male infants are more in number than among female giant baby. 5. Duration of labor tends to be extended more with multipara or grandpara. 6. Most of the giant babies are delivered vaginally C-sections are performed mainly under the diagnosis of C.P.D. 7. Malpresentations amount to a 2.6% of the total of 536 babies. 8. No maternal mortality was found in connection with the delivery of giant baby. 9. There is a total of 26 cases accinoabued with bleeding more than 500cc, which is about a 5.8% 10. The death rate of giant baby is 2.25% of 536 cases.

정상임신 태반에 있어서의 Betaglucuronidase 및 Esterase의 활성도

이경희(KH Lee),장윤석(YS Chang) 대한산부인과학회 1975 Obstetrics & Gynecology Science Vol.18 No.3

1) Beta-glucuronidase의 활성도는 조기태반에서 보다 만기태반에서 그 활성도가 전체적으로 증강되어 있었다. 2) Esterase의 활성도는 beta-glucuronidase와는 반대로 기기태반에서 만기태반보다 전체적으로 높은 활성도를 보였다. The placenta is one of the most dynamic structures in human body. during the past few decades many histochemical studies by others have contributed greatly to our knowledge of the precise localization of certain metabolic activities in the placenta of human body. It is the purpose of this report to describe certain histochemical reactions of the normal human placenta during its maturation, and to present interpretation of the passible fuctional significance of these reaction. Placental enzymes were studied histochemically in the histologically normal placenta from 25 early pregnant and 50 term pregnant women. Beta-glucuronidase activity was greater in term placenta than early placenta in general and greatest concentration layer, moderate concentration in blood vessels and stroma and scanty in chorionic plate. Esterase activity was, in contrast with beta-glucuronidase, greater in early placenta than term placenta in general and greatest concentration were noted in the chorionic plate, moderate concentration in villi, scanty in blood vessels and stroma.

만삭자궁 파열 3례

김기종(KC Kim),이경희(KH Lee),김용성(YS Kim),이진용(JY Lee) 대한산부인과학회 1971 Obstetrics & Gynecology Science Vol.14 No.12

만삭자궁 파열 3례를 보고하는 바이다. Rupture of the uterus constitues one of the most serious complication of the pregnancy. It is not frequent disease, but it caused 5% of all maternal death. Although the overall incidence has remained fairly constant recently, there has been a realtive change in the number of ruptures attributed to the particular cause. Rupture of the uterus due to obstetrical trauma has shown a marked decrease; this is the result of careful management. The resultant increase in the incidence of cesarean section, however, has brought about a relative increase in incomplete (silent dehiscence) uterine ruptures. We experienced 3 cases of uterine rupture recently: 1-st case was traumatic rupture due to careless use of exytocin by midwife. 2-nd case was spontaneous rupture of cesarean scar during labor. 3-rd case was traumatic rupture of previous cesarean scar by the administration of oxytocin at local clinic.

황체 호르몬방출 자궁내장치가 난소 기능에 미치는 영향

김승욱(SW Kim),이경희(KH Lee) 대한산부인과학회 1983 Obstetrics & Gynecology Science Vol.26 No.12

In order to observe the effect of intra-uterine devices releasing 2ug of levonorge strel and 25ug of progesterone on ovarian function and to monitor their effect on menstrual bleeding patterns, twenty healthy subjects were randomly assigred to one of the two devices which were obtained from the Special Programme of Research in Human Reproduction of the World Health Organisation. After IUD insertion, each subjects were requested to attend the clinic at monthly intervals for six months bet ween days 20~25 following the first day of menstruation to have blood withdrawn for the estimation of estradiol and progesterone. Each subjects were given menstrual diary card to monitor menstrual bleeding patterns. Percent of cycles with blood progesterone level less than 3ng/ml was l3.5out of total 52 postinsertion cycles measured in 2ug levonorgestrel IUD group and l8.8 out of 48 postinsertion cycles in 25ug progesterone IUD group whereas the same rates of pretreatment cycles were 20 and 30 respectively in the two groups, sugges ting that both devices have no effect on ovulation. Menstrual bleeding pattens of subjects wearing 2ug levonorgestrel IUD were found to be different from the control cycles by being shorter and scanty expect during the first 3 months. Two of 9 subjects wearing 25ug progesteone IUD had their devices removed because of prolonged intermenstrual spotting, , however, the remaining 7 were found to have shorter duration and scanty amount of menstruation than those of control cycles.

초기임신인공중절 직후에 삽입된 자궁내장치 TCu 220C , MLCu 250과 IPCS 52의 피임효과에 관한 임상연구

김승욱(SW Kim),이경희(KH Lee) 대한산부인과학회 1985 Obstetrics & Gynecology Science Vol.28 No.6

A clinical study with 2 kinds of copper and one progesterone releasing intrauterine devices was performed to assess their contraceptive effectiveness and acceptability in Korean women. Devices used in the present study were copper-T 220C (TCu 220C), multiload copper 250 (MLCu 250) and Intrauterine Progesterone Contraceptive System 52 (IPCS 52) which releases 25㎍ of progesterone daily. A total of 103 TCu 220c, 100 MLCu 250 and 97 IPCS 52 were inserted following termination of early pregnancy and the total months of use accumulated were 2,246 months with TCu 220C and 2,155 months with MLCu 250 during the 36 months of study period and 1,116 months were accumulated with IPCS 52 during the 18 months of study period. Life table analysis of the first segment event rates at the end of first year showed the pregnancy rate to be 1.0 per 100 insertion with TCu 220C, zero with MLCu 250 and the expulsion rate to be 4.0 with TCu 220C and 2.0 with MLCu 250C and medical removal rate to be 6.8 with TCu 220C and 14.7 with MLCu 250. Neither pregnancy nor spontaneous expulsion was observed during the second and third year of observation in both TCu 220C and MLCu 250 users. Medical removal rates at the end of second year obtained with TCu 220C was 18.5 per 100 insertion and the rate obtained with MLCu 250 was 22.9, whereas the same rates at the end of third year obtained with TCu 220C and MLCu 250 were 24.3 and 25.3 respectively. The pregnancy rates at the end of 12 and 18 months obtained with IPCS 52 were 0 and 1.3, the expulsion rate were 8.3 and 9.4, and the medical removal rates were 24.1 and 30.1 per 100 insertions. The nature of side effects commonly observed were spotting, bleeding, pain and increased vaginal discharge. The incidence of pain observed was highest in the MLCu 250 group and slightly lower in the IPCS 52 and TCu 220C groups. The incidence of spotting observed was remarkably higher in the IPCS 52 group than those of copper IUD groups, but the incidence of menorrhagia was higher in the copper IUD groups than that of progesterone device. This present study suggests that the two copper bearing IUDs, i.e. TCu 220C and MLCu 250 have higher contraceptive effectiveness and acceptability than the progesterone releasing IUD, i.e., IPCS 52, however no great difference in effectiveness and acceptability exist between TCu 220C and MLCu 250.

진공흡인에 의한 초기임신중절술에 있어서 전동식과 수동식흡인기의 효용차

백원영(WY Paik),이경희(KH Lee),김승욱(SW Kim) 대한산부인과학회 1986 Obstetrics & Gynecology Science Vol.29 No.2

진공흡인에 의한 초기임신중절술에 있어서 전동식과 수동식흡인기의 효용차 Suction curettage has been shown to be an effective and safe method of performing induced abortion during the first trimester of pregnancy and the vacuum needed for the suction curettage will usually be provided by an electrically operated pump. Unfortunately electricity supply may not always be available in certain area and an alternative source of vacuum will be needed. This study was undertaken to compare the practicability and safety of using mechanical pump developed by the Battelle Foundation for the first trimester abortion and to compare the outcome with that of abortions performed by the conventional electrically operated pump. A total of 460 cases of first trimester pregnancy were recruited and randomly allocated to either the mechanical or electrically operated pump group. After performing abortion, the volume of aspirates, the duration of the procedure and the number of times the cannulae was introduced into the uterus were recorded and both the immediate and delayed complications were assessed. The mean duration of gestation was 8.6 weeks in the mechanical pump group and 8.7 weeks in the electrical pump group. The average duration of procedure from the start of dilatation was 6.1 minutes in the mechanical pump group and 5.6 minutes in the electrical pump group. The mean volume of aspirate in the mechanical pump group was 101.2ml and mean volume in the electrical pump group was 104.2ml. The incidence of complication in the mechanical pump group was 3.1% whereas the same in the electirical pump group was 3.5% and the nature of complication were similar in both groups. From the above findings, it is concluded that the mechenical pump is safe for use in performing first trimester abortion although it is not as convenient as the electrically operated pumps.