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RISS 인기검색어
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- 저자 : 윤영범(Yong Bum Yoon) (검색결과 3 건)
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내시경적 (內視鏡的) 역행성 췌담관조영술의 (膵膽管造影術) 합병증에 (合倂症) 대한 Gabexate mesilate ( FOY ) 의 예방적 (豫防的) 효과
송인성(In Sung Song),김정용(Chung Yong Kim),윤영범(Yong Bum Yoon),배순기(Soon Kie Bae),송제일(Je Il Song) 대한소화기학회 1981 대한소화기학회지 Vol.13 No.2
N/A The development and prevalence of endoscopic retrograde cholangiopancreatography(ERCP) has resulted in great progress in the diagnosis of the disease of the pancreas, and biliary tract. At the same time, however, the rise of serum amylase level has been often point out as the complication of ERCP. To assess the effect of synthetic protease inhibitor, Gabexate mesilate(FOY), in hyperamylasemia following ERCP, the authors carried out a controlled trial in 39 patients who were underwent ERCP under the impression of pancreatic or biliary system disease. Of them 20 patients were allocated to FOY@ treated group and 10 patients to control group. The following results were obtained: 1) There was no significant difference in serum amylase level between FOY treated group and control group before ERCP, however significant difference was observed in seram amylase level at 2 hour and 2 day after ERCP between FOY treated group and control group Before ERCP the serum amylase level was 107. 6 45. 1 I.U./dl in control group and 105. 7+-42.1 I.U./dl in FOY treated group.At 2hour after ERCP the serum amylase level was 186.7 +-150.1 I.U./dl in control group and 103.2+-47.9 I.U./dl in FOY treated group. On 2nd day after ERCP, the serum amylase level was 167.7+-84. 1 I.U,/dl in control group and 109.6+-59.1 I.U./dl in FOY treated group 2) The change in serum amylase levels at 2 hour and 2 day after ERCP by the extent of visualization showed a tendency that a greater extent of visualization was associated with a higher incidence of serum amylase levels. Such a tendency was more pronounced in control group and the mean serum amylase level was significantly higher in the control group. 3) FOY did not cause any serious side effect such as shock, fall of blood pressure, itching, eruption, chest pain etc. in all cases. 4) There was some report that FOY has a relaxant action on the Oddis sphincter and helps the cannulation to the opening of Papilla of Vater, however it more depended upon the skill of the endoscopist, anatomical variation of the Papilla of Vater and FOY did not give any great advantage to the cannulation.
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이진호(Jin Ho Lee),김나영(Na Young Kim),윤한두(Han Doo Yoon),유권(Kwon Yoo),정영화(Young Hwa Chung),이효석(Hyo Suk Lee),정현채(Hyun Chae Jung),윤영범(Yong Bum Yoon),송인성(In Sung Song),김정룡(Chung Yong Kim) 대한내과학회 1989 대한내과학회지 Vol.36 No.2
N/A The gastrointestinal polyp is a premalignant lesion, especially villous or large adenoma in the colorectum, which should be removed. Polyps in the gastrointestinal tract can be removed by surgical excision, cryotherapy, electrocoagulation, or contact radiotherapy with some limitations. So, the usefullness, efficacy and safety of endoscopic laser therapy were investigated prospectively in 41 patients. We treated 29 cases of gastric polyps in 24 patients and 23 cases of colorectal polyps in 17 patients with the Nd: YAG laser from May 1986 to July 1988. The patients were analyzed by grouping those with gastric polyps and those with colorectal polyps. The patients with gastric polyp were most frequenty in the 6th decade and the majority were in female. But, in the case of colorectal polyps, 7th decade and male respectively. Gastric polyps were most frequently found in the gastric body and as Yanada type III. Colorectal polyps were found evenly in the rectum, sigmoid colon, descending colon, and Yamada type I were most fre- quent. The size of gastric and colorectal polyps was generally less than 1 cm in diameter. Histologically, gastric polyps were more frequently hyperplastic than adenomatous but colorectal polyps were more adenomatoous than hyperplastic. We irradiated the Nd: YAG laser along a flexible waveguide through the endoscope. The energy required to remove the polyps was increased according to their size; in gastric polyps, 458 J±303 (mean±S.D) for less than 0.5cm, 1336S605 for greater than 0,5 cm and less than 1.0 cm, and 2170±266 for greater than 1.0 cm; in colorectal polyps, 366±303 for less than 0.5 cm, 935±456 for greater than 0.5 cm and less than 1.0 cm, and 2099707 for greater than 1.0 cm. A patients were followed-up in 1-4 weeks by endoscopy. The post-laser therapy ulceraton developc4 in 10 cases of gastric polyp patients (59%) and in 5 cases of colorectal polyp patients (42%) without major complications such as perforation, hemorrhage or stricture. The polyps were removed completely within two sessions of laser irradiation. Thus, we concluded that laser therapy can be very effective and saft in the removal of gastrointestinal polyps in terms of the number of sessions and complications respectively. A long term follow-up may be needed for changes around the area of laser injured tissues.
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