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- 저자 : 윤세효 ( She Yo Yune ) (검색결과 1 건)
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위장관 ; 장폐쇄를 동반한 크론병 환자에서 내과적 치료에 대한 반응 예측 인자
김은 ( Eun Kim ),윤세효 ( She Yo Yune ),하정민 ( Jung Min Ha ),이우주 ( Woo Joo Lee ),황지원 ( Ji Won Hwang ),민신영 ( Sin Young Min ),홍성노 ( Sung Noh Hong ),장동경 ( Dong Kyung Chang ),이풍렬 ( Poong Lyul Rhee ),김재준 ( Jae J 대한소화기학회 2013 대한소화기학회지 Vol.62 No.4
Background/Aims: Crohn`s disease is a chronic inflammatory bowel disease. Stricture is a very important indication for surgical intervention as strictures can lead to intestinal obstruction. Strictures can be divided into inflammatory and fibrous strictures. Intestinal obstruction due to inflammatory stricture is expected to be resolved with medical treatment. However, factors that can predict the response to medical treatments are unknown. In the present study, we aimed to identify the factors that can predict the response to medical treatments in Crohn`s disease patients with intestinal obstruction. Methods: Data were collected by retrospectively reviewing the medical records of patients with Crohn`s disease who visited the emergency department at Samsung Medical Center in Seoul from January 1, 2000 to December 31, 2010 because of intestinal obstruction. Based on the response to medical treatments, we classified the patients as responders and non-responders and compared the clinical, biochemical, and radiological findings of the two groups. Results: A total of 39 patients were enrolled. Twenty-nine patients responded to medical treatments whereas 10 patients did not. Significant differences were observed between the two groups in terms of vomiting and duration of disease before the development of obstruction. Conclusions: Patients who responded to the medical treatments exhibited a higher incidence of vomiting and longer duration of disease before the development of obstruction. However, further prospective studies are needed to identify the factors that can predict the response to medical treatments. (Korean J Gastroenterol 2013;62:213-218)
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