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- 저자 : 유우근(Woo-Geun Yu) (검색결과 3 건)
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Botryoid Odontogenic Cyst on Mandibular Anterior and Both Body Area: a Case Report
남정훈,김다영,박영주,안장훈,강태인,박미희,유우근,김보균,이정원,김정희,Nam, Jeong-Hun,Kim, Da-Young,Park, Young-Ju,Ahn, Jang-Hoon,Gang, Tae-In,Park, Mi-Hee,Yu, Woo-Geun,Kim, Bo-Gyun,Lee, Jung-Won,Kim, Jung-Hee Korean Association of Maxillofacial Plastic and Re 2010 Maxillofacial Plastic Reconstructive Surgery Vol.32 No.4
Botryoid odontogenic cyst (BOC) is considered a rare multilocular variant of the lateral periodontal cyst. In this report, a 67-year-old male visited with chief complaint of severe mobility on mandibular incisors. Multilocular radiolucent lesion was seen from the right premolar to the left premolar area, involving almost the whole mandible. Histologically, the botryoid odontogenic cyst showed focal nodular thickening of the lining epithelium. These thickening often showed swirling appearance of the cells. Cyst enucleation and bone graft on mandible anterior and both body area were performed under general anesthesia, and postoperative healing was favorable without recurrence.
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백서 두개골결손모델에서 실크단백과 골형성단백 이식체가 골재생에 미치는 영향
남정훈(Jeong-Hun Nam),노경록(Kyung-Lok Noh),방은오(Eun-O Pang),유우근(Woo-Geun Yu),강응선(Eung-Sun Kang),권해용(Hae-Yong Kweon),김성곤(Seong-Gon Kim),박영주(Young-Ju Park) 대한구강악안면외과학회 2010 대한구강악안면외과학회지 Vol.36 No.5
Introduction: This study evaluated the capability of silk fibroin (SF) and recombinant human bone morphogenetic protein-2 loaded SF (SF-BMP) as a bone defect replacement matrix when grafted in a calvarial bone defect of rats in vivo. Materials and Methods: A total 70 calvarial critical size defects (5.0 mm in diameter) made on 35 adult female Sprague-Dawley rats were used in this study. The defects were transplanted with (1) rhBMP-2 loaded silk fibroin graft (SF-BMP: 0.8+10 μg), (2) Silk fibroin (SF: 10 μg), and (3) no graft material (Raw). The samples were evaluated with soft x-rays, alkaline phosphatase activity, calcium/phosphate quantification, histological and histomorphometric analysis at postoperative 4 and 8 weeks. Results: The SF-BMP group (48.86±14.92%) had a significantly higher mean percentage bone area than the SF group (24.96±11.01%) at postoperative 4 weeks.(P<0.05) In addition, the SF-BMP group (40.01±12.43%) had a higher % bone area at postoperative 8 weeks than the SF group(33.26±5.15%). The mean ratio of gray scale levels to the host bone showed that the SF-BMP group (0.67±0.08) had a higher mean ratio level than the SF group (0.61±0.09) at postoperative 8 weeks. These differences were not statistically significant.(P=0.168 and P=0.243, respectively) The ratio of the calcium and phosphate contents of the SF-BMP (0.93±0.22) group was lower than that of the SF (1.90±1.42) group at postoperative 4 weeks. However, the SF-BMP group (0.75±0.31) had a higher Ca/PO4 ratio than the SF (0.68±0.04) at postoperative 8 weeks. These differences were not statistically significant.(P=0.126 and P=0.627, respectively) For the bone-specific alkaline phosphatase (ALP) activity, which is recognized as a reliable indicator of the osteoblast function, the SF-BMP (23.71±8.60 U/L) groups had a significantly higher value than the SF group (12.65± 6.47 U/L) at postoperative 4 weeks.(P<0.05) At postoperative 8 weeks, the SF-BMP (21.65±10.02 U/L) group had a lower bone-specific ALP activity than the SF group (16.72±7.35 U/L). This difference was not statistically significant.(P=0.263) For the histological evaluation, the SF-BMP group revealed less inflammation, lower foreign body reactions and higher bone healing than the SF group at postoperative 4 and 8 weeks. The SF group revealed more foreign body reactions at postoperative 4 weeks. However, this immunogenic reaction decreased and the remnant of grafted material was observed at postoperative 8 weeks. For histomorphometric analysis, the SF-BMP group had a significantly longer bone length to total length ratio than those of the SF group at postoperative 4 and 8 weeks.(P<0.05) Conclusion: The rhBMP-2 loaded silk fibroin graft revealed fewer immunoreactions and inflammation as well as more new bone formation than the pure silk fibroin graft. Therefore, silk fibroin may be a candidate scaffold for tissue engineered bone regeneration.
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기능적 부하 후 “Short Implant” 주변의 골 흡수에 대한 방사선학적 연구
박영주(Young-Ju Park),남정훈(Jeong-Hun Nam),노경록(Kyung-Lok Noh),연병무(Byoung-Moo Yeon),유우근(Woo-Geun Yu),이정원(Jeong-Won Lee),안장훈(Jang-Hun Ahn),강태인(Tae-In Gang),박미희(Mi-Hee Park) 대한치과의사협회 2010 대한치과의사협회지 Vol.48 No.8
Purpose: The short dental implant is considered as possible solution in the alveolar bone height deficient cases. The aim of this study was to evaluate clinical availability of short implants by measuring the marginal bone loss of short length implants and comparing with that of conventional length implants. Materials and Methods: The groups were composed of patients who had received at least one implant. The samples of this study were selected from patients who with functional loading after prosthetic treatment for 1 year follow up period. The implants with a length of 5.7㎜ and 6㎜ were considered short. (Bicon Dental implants, USA). The experiment group was composed of 4.5×6㎜, 5×6㎜, 6×5.7㎜ implants (total 18 implants were placed in 14 patients, 8 on maxilla, 10 on mandible). The control group was composed of 4.5×8㎜, 5×8㎜, 4.5×11㎜, 5×11㎜. All implants were selected only by implants placed on molar area. We evaluated marginal bone loss in radiographic images at baseline (implant loading) and 3, 6, 12 months after loading. Additionally, crown-to-implant ratio was evaluated, and marginal bone loss according to crown-to-implant ratio after functional loading was analyzed. Results: The short implant group had a mean marginal bone level of -0.52±0.69 ㎜; the 8㎜ group, -0.22±0.82㎜; and the 11㎜ group, -0.10 ± l.09㎜ after 1 year of functional loading. But significant differences were not detected between three groups at every follow-up period. Crown-to-implant ratio in short implant group was 1.55±0.23; 8㎜ group was 1.15±0.18; and 11㎜ group was 0.92±0.15. Additionally, significant differences between three groups were founded. (P<.0001) The greatest marginal bone loss after 1 year follow-up was founded at crown-to-implant ratio 1-1.49 range in short implant. Conclusion: The marginal bone loss of short implants was comparable to that of long implants. So, the short implants can be a clinically acceptable option.
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