http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : 유병철(Byung Chul Ryoo) (검색결과 1 건)
- 무료
- 기관 내 무료
- 유료
-
B 형 만성활동성간염 치료제로서 합성 α - Interferon 의 효용성
이호심(Ho Sim Lee),임종찬(Jong Chan Lim),이일남(Il Nam Lee),조현덕(Hyun Duk Cho),유병철(Byung Chul Ryoo),박실무(Sill Moo Park) 대한내과학회 1990 대한내과학회지 Vol.39 No.3
N/A Fifty eight patiens with chronic active hepatitis were entered into a therapeutic trial of 12-week period of recombinant α-interferon therapy. All patients were positive for both HBsAg and HBeAg. During the 13 to 62-week period of follow-up, 24 of 58 (47%) treated patints became negative for serum HBeAg but in 9 of these HBeAg reappeared in their serum. Fifteen patients (30%) were also positive for serum Anti-HBe but 5 of this lost Anti-HBe from serum. 9 patents positive for initial HBV DNA lost their DNA from serum. Responders had a marked improvement in serm aminotransferase activities. Seroconversion rate of female (5/9, 56%) was seemed to be higher than that of male (19/43, 45%). Comparison of responders to non-responders indicated that a high initial level of serum aminotransferuse and a severe form of hepatic histology correlate best with response to interferon herapy. 45 of 58 (78%) patients showed various adverse reactions, such as myalgia (59%), fatigue (57%), fever (52%), nausea and anorexia. Transient decrease in peripheral leukocyte and platelet count were also noted. These findings suggest that α 12-week course of recombinant α-interferon therapy would be effective and safe in approximately half of patients with chronic active hepatitis B.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
