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백서 복강내 2.7% Sorbitol Plus 0.54% Mannitol 주입후 폐와 신장의 병리조직학적 변화
우중원,이창규,류현열 고신대학교 의학부 2000 高神大學校 醫學部 論文集 Vol.15 No.1
Background The purpose of this study was to see the serum electrolyte changes and histologic alteration in organs after experimentally induced water intoxication in the rats. Methods 2.7% sorbitol plus 0.54% mannitol solution was infused into the peritoneum of 80 Sprague-Dawley rats by each amounts of 225, 250, 275 or 300ml/kg. Those rats were sacrificed at 1, 3, 6, 24 hours after intraperitoneal infusion, and then we compared the serum electrolyte changes and histologic alteration in lung and kidney according to each times. Results The serum sodium and chloride were maximally decreased at 6 hours after infusion of sorbitol plus mannitol and then nearly returned to the normal range at 24 hours after infusion. The lungs showed mononuclear cell infiltrations. The kidneys showed hemorrhages, capillary congestions, tubular atrophy in renal cortex and corticomedullary junction regardless of infusion amount and time, And these changes in the lung and kidney persisted after 24 hours. Conclusions In this experimental study of water intoxication using rats, the serological changes returned to nearly normal ranges at 24 hours, but histopathologic changes in the lung and kidney persisted to 24 hours after infusion.
백서 복강내 2.7% Sorbitol Plus 0.54% Mannitol 주입 후 폐와 신장의 병리조직학적 변화
우중원,이창규,류현열 고신대학교(의대) 고신대학교 의과대학 학술지 2000 고신대학교 의과대학 학술지 Vol.15 No.1
Background : The purpose of this study was to see the serum electrolyte changes and histologic alteration in organs after experimentally induced water intoxication in the rats. Methods : 2.7% sorbitol plus 0.54% mannitol solution was infused into the peritoneum of 80 Sprague-Dawley rats by each amounts of 225, 250, 275 or 300ml/kg. Those rats were sacrificed at 1,3,6,24 hours after intraperitoneal infusion, and then we compared the serum electrolyte changes and histologic alteration in lung and kidney according to each times. Results : The serum sodium and chloride were maximally decreased at 6 hours after infusion of sorbitol plus mannitol and then nearly returned to the normal range at 24 hours after infusion. The lungs showed mononuclear cell infiltrations. The kidneys showed hemorrhages, capillary congestions, tubular atrophy in renal cortex and corticomedullary junction regardless of infusion amount and time. And these changes in the lung and kidney persisted after 24 hours. Conclusions : In this experimental study of water intoxication using rats, the serological changes returned to nearly normal ranges at 24 hours, but histopathologic changes in the lung and kidney persisted to 24 hours after infusion.
자동물류취급 시스템의 설계 및 실시간 운용에 관한 연구
김종원,우중원 대한기계학회 1994 大韓機械學會誌 Vol.34 No.2
이 글에서는 무인운반차(AGV: Automated Guided Vehicle), 자동창고 (AS/RS: Automated Storage/Retrieval System), 콘베이어시스템, 바코드시스템 등의 자동물류취급시스템을 응용하여 극단적인 다품종 소량생산체제의 납기단축효과와 가동효율을 어떻게 향상시킬 수 있는지를 저 자들이 직접주도하여 설계 . 설치 . 가동중인 사례를 통하여 실증적으로 밝혀보고자 한다.