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폐의 소세포암종에서 Synaptophysin, Neuron-SpecificEnolase, Chromogranin A, Neurofilarnent 항체들의 감수성에 대한연구
노종섭 ( Jong Sup Roh ),왕성수 ( Sung Su Wang ),이정아 ( Chung A Lee ),곽효일 ( Hyo Il Kwak ),윤기중 ( Ki Jung Yun ) 대한임상검사과학회 1998 대한임상검사과학회지(KJCLS) Vol.30 No.3
A variety of benign and malignant tumors may arise in the lung, but the bronchogenic carcinoma is majority. Among the brochogenic carcinomas, small cell carcinoma is a histologically distinctive type, and it is higly malignant and chemosensitive To evaluate of sensitivity of neuroendocrine markers such as synaptophysin, neuron-specific enolase(NSE), chrorrogranin A and neurofilament antibodies, we studied the small cell carcinoma of lung on the 32 paraffin embedded tissues. The sensitivities of synaptophysin, NSE, chrorrogranin A and neurofilarrent were ``irl.5%, 31.30/0, 25%, and l000~ respectively, Above result indicates that neurofilament and synaptophysin antibodies are good for diagnosis of small cell carcinoma of the lung.