身體畸形恐怖症(Dysmorphophob)1例를 통해 본 診斷上의 問題點

吳東財,張煥一,全成一 서울大學校 醫科大學 精神科學敎室 1992 精神 醫學 Vol.17 No.1

Cognitive-Behavioral Treatment of Obesity: a clinician's guide

오동재 한국인지행동치료학회 2004 인지행동치료 Vol.4 No.1

정신분열증의 사건관련유발전위에 대한 연구(Ⅰ) : 정신분열증 환자의 사건관련유발전위 P3 in the Schizophrenics

오동재,장환일 大韓睡眠-精神生理學會 1994 수면·정신생리 Vol.1 No.1

家庭主婦의 家族緊張度에 관한 硏究 : 神經症 및 對照群의 比較 Comparison between Neurotic and Control Groups

張煥一,吳東財 大韓神經精神醫學會 1987 신경정신의학 Vol.26 No.2

The purpose of this study was to investigate the strains of housewives as stress factors in the family of Korean society. The “Family Strain Questionnaire(FSQ)”was applied to the 99 neurotic housewives who are going treatment at psychiatric outpatient clinic of university and general hospitals and 242 normal control housewives from January to April in 1986. The FSQ is a self-rating questionnaire, consisting of 81 items which can be subgrouped in 14 areas, and is expected to reply basing on response choice in FREQUENCY and SEVERITY with 3 digit selection. The results were summarized as the followings; 1) The FSQ was confirmed highly reliable through the method of split-helf.(frequency: r=0.935, severity: r=0.941) 2) The total scores of both frequency and severity were highly correlated between neurotic and normal control housewives. 3) The frequency and severity of each 81 items were compared between neurotic and normal control housewives. While ‘Marital strain’and ‘Undersirable events/situation’were significantly higher in neurotic housewives than controls. ‘Work-related’was significantly higher in control housewives than in neurotic in terms of frequency and severity. 4) Each items were ranked according to the scores of frequency in both groups While ‘My own physical illness’was firstly ranked in neurotic housewives ‘Not satisfied with daily housework’was control housewives. 5) No significant difference was seen in total scores of FREQUENCY of strains, but significant difference was seen in total scores of SEVERITY of strains between both groups. Those results were discussed in relation with the sociocultural characteristics of Korean society and were compared with those of other researchers.

精神分裂病에서 血漿 Cyclic Adenosine 3', 5' -Monophosphate(Cyclic AMP)에 關한 硏究

田珍叔,張煥一,吳東財 大韓神經精神醫學會 1986 신경정신의학 Vol.25 No.2

The authors estimated plasma cyclic AMP in 10 schizophrenic patients who had not received neuroleptic treatment and who had received neuroleptic treatment for 2 weeks, and 6 normal volunteers. 1)Though slightly lower than controls, plasma cyclic AMP in schizophrenics(15.95±3.23 pmol/100㎖)(mean±standard error)was not significantly different from controls. 2)2 weeks after medication with neuroleptics, the plasma cyclic AMP in schzophrenics(13.35±1.16 pmol/100㎖)was lower than drug-free groups, but there is no statistical significance. 3)Plasma cyclic AMP in males(20.00±6.10 pmol/100㎖ in schizophrenics, 11.17±1.45 pmol/100㎖ in males) were somewhat higher than controls, but there is no statistical significance.

경련과 뇌 혈액 관류장애를 동반한 Zipeprol 남용 6례

김종우,장환일,오동재 大韓神經精神醫學會 1994 신경정신의학 Vol.33 No.2

Zipeprol, an antitussive agent, abuse has recently increased among adolescents. The authors experienced 6 cases of Zipeprol abuse complicated with convulsion and cerebral perfusion defects. They all had experienced drowsy consiciousness, euphoria, and hallucination during the intoxication of zipeprol. One of them had experienced aggressive impulses rather than euphoria. Another one had experienced fear due to persecutory delusion. They habitually used the drug in doses 1.5-7 times higher than the recommended dose. They all, who had never had seizure history, had generalized tonic-clonic seizures during the period of intoxication. The withdrawal symptoms, which were sleep difficulty, headache and anxiety, appeared 1-4 days after discontinuation of the drug and persisted for 3-4 days. The single photon emission tomography of the brain showed multiple defects of perfusion in the temporal, occipital cortex and basal ganglia.

동성 강간 피해자에서 발생한 외상후 자극 장애 1례

장환일,반건호,이혁,오동재 大韓神經精神醫學會 1995 신경정신의학 Vol.34 No.1

While the homosexual rape is not rare in Korea, but there has not been but one report about that. Authors reported a 21-year-old man had post-traumatic stress disorder after being raped by a roommate. When he was 18 years old, he was raped by a roommate in high school dormitory. He had symptoms of post-traumatic stress disorder after the accident. As time went by, he partially recovered. When he was recruited by the army, he had to sleep with men, which reminded him of the previous rape experience. He had acute psychotic symptoms and panic attacks. After environmental manipulation, supprotive pschyotherapy and pharmacotherapy, he improved. As we reviewed studies about female rape victims, we noticed that the psychological responses of a male homosexual rape victim were similar to that of female rape victims and that when the victim was forced to confront the situation which remind of the accident, he relapsed (or exacerbated).

국군○○병원 정신과 입원환자의 추적조사

반건호,오동재 大韓神經精神醫學會 1995 신경정신의학 Vol.34 No.2

Objects : This study was aimed at 1) the comparison between rejoin and CD groups and 2) the rate of diagnostic agreement and evaluation on discharge between psychiatrists in the army hospitals. Method : This study was designed to follow up 150 inpatients in the department of Neuropsychiatry of 00 Armed Forces Hospital(abbreviated as field hospital) or evacuated via that field hospital from July 1, 1991 to December 31, 1992. They were soldier below the rank of sergeant first class. Results : Among 150 patients, 99 soldier rejoined their unit after proper treatment(abbreviated as rejoin group) and 51 patients were discharged from the service(abbreviated as CD group, compassionate discharge group) in field hospital, evacuation hospital or general hospitals. The rate of onset of psychiatric illness before enlistment was 58.8% in CD group. In rejoin group, 75.7% had the onset of psychiatric illness before private first class. In diagnosis, adjustment reaction and conversion disorder patients were 73.7% in rejoin group. In CD group, almost all were epileptics, major depressions, personality disorders, or mental retardations. Average duration of hospitalization was 76.9±54.6 day in all subjects. There was a statistically significant difference, especially for general hospital(F=32.6176, df=2, p〈.01). Evaluation on discharge was as follows : 1) 34.0% were discharged from the service because of psychiatric illness. 2) 27.3% were expected to serve without further psychiatric symptoms or problems. 3) Even though it is not resolved, 26.7% were expected to serve. The rate of diagnostic agreement between doctors in field-evacuation-general hospital was 84.2%. Conclusion : We have to keep in mind that 58.8% of CD group began to show their psychiatric symptoms and 49.0% had psychiatric problems prior to enlistment. The critical period for the rejoin group was from the beginning of private to private first class. The average duration of hospitalization in the army was longer than that of civilian hospitals. One of the main reasons was due to the characteristic of the evacuation system in the army. With due regard to the evluation on discharge and the rate of diagnostic agreement, army doctors, especially psychiatrists, were excellent at diagnosing and treating the psychiatric patients.

Lithium 유지치료 중 발생한 갑상선기능저하증의 임상지침을 위한 연구(I) : Clinical Importance of Antithyroid Antibody 항갑상선 항체의 임상적 중요성

김진우,장환일,송지영,조성욱,윤도준,양기영,오동재 大韓神經精神醫學會 1995 신경정신의학 Vol.34 No.6

This study is a cross-sectional one for clinical reference of hypothyroidism during lithium maintenance therapy, focusing on antithyroid antibody. Thyroid function including T₃,T₄,TSH, thyroid microsomal antibody, and thyroglobulin antibody were evaluated in 60 patients, given the diagnosis of bipolar disorder by DSM-Ⅲ-R criteria. Thirty-five patients had never previously received lithium and the remaining 25 patients were on chronic lithium treatment(mean 22 months). A visible or palpable goiter was not found in any patient. No case of symptomatic hypothyroidism was observed, but subclinical hypothyroidism was present in 16% of patients on lithium, conpmared with 5.7% in the pre-lithium group. The prevalence of antithyroid antibody was 32% in the lithium group, and 8.6% in the pre-lithium group. The difference of prevalena rate was statistically significant(p<0.05). In antibody-positive lithium-treated patients, the mean age was 41 years and the prevalance of thyroid antibody was higher in women. And the subclinical hypothyroidism was more prevalent in antibody-positive patients than in antibody-negative patients. But the prevalence of antithyroid antibody did not significantly correlate with the duration of lifhium treatment in this study. This study shows that the thyroid function test including microsomal antibody and thyroglobulin antibody is very important for early detection of the hypothyroidism when treating bipolar patients with lithium.

본태성 고혈압환자의 정신의학적 연구 : 정신병리와 스트레스 지각을 중심으로 Focused on Psychopathology and Stress

오동재,윤희웅,장환일 大韓神經精神醫學會 1994 신경정신의학 Vol.33 No.4

There is a welath of evidence to support an association between psychological factors and raised blood pressure. And many researchers have said that stress would induce hypertension. We assessed the differences in psychopathology and stress perception between 109 diagnosed hypertensives with essential hypertension in the Department of Internal Medicine and 112 normal controls within a normal range of blood pressure, by using the Symptom Check List-90-Revision(SCL-90-R), the Global Assessment of Recent Stress Sacle(GARS), the State-Trait Anxeity Inventory(STAI),and the Beck's Depression Inventory(BDI). The results were as follows: 1)Hypertensive showed significantly high somatization, obssessive-compulsive, anxiety, phobic anxiety and psychoticism scores on the SCL-90-R, but there was no significant difference between the scores of stress perception of hypertensives and those of normal controls on the GARS, For anxiety and depression, hypertensives showed significantly high state anxiety, trait anxiety and depression scores on both the STAT and BDI. 2)Among hypertensives, those taking benzodiazepine showed significantly high psychopathology and stress. 3)In hypertensive, we couldn't find any significant correlation between the scores of the SCL-90-R, STAI, BDI, and GARS and their blood pressures. In normal controls, there were significant positive correlations between systolic blood pressure and the scores of stress perception in the sickness or injury and the overall global on the GARS. From the results, we concluded that hypertensives had a higher degree of psychopathology than normotensives and that there was no significant correlation between blood pressures and psychopathology and stress in hypertensives, but that there were significant positive correlations between systolic blood pressure and scores of stress perception in the sickness or injury and the overall global on the GARS in normal controls.