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고환종양의 태반생성물질 분포에 관한 면역조직화학적 연구
염석호,염범우,최종상 고려대학교 의과대학 1988 고려대 의대 잡지 Vol.25 No.1
There were many efforts to find out specific tumor markers of variable tumors for the purpose of early cancer diagnosis, evaluation of cancer treatment and early detection of cancer recurrence. Now many placental hormones and proteins are believed to be produced by tumors of various origins. Among these, PAP, SPI, PAPP-A, HCS and β-HCG are included. Testicular tumors, especially in nonseminomatous germ cell tumors, are known to produce several placental products such as AFP and HCG. But there is no report specific for tumor marker of seminoma. Therefore, the author tried to evaluate presence of above 5 kinds of placental products in the tissue of testicular seminoma, teratoma, choriocarcinoma, embryonal carcinoma, yolk sac tumor, embryonal rhabdomyosarcoma and malignant lymphomaby ABC method, of immunoperoxidase stain, The results are followings: 1. All 5 cases of seminoma revealed strong positive reaction along the cell membrane to anti-PAP antisera. 2. Syncytiotrophoblast of choriocarcinoma and glandular epithelial cell in teratoma showed positive reaction to anti-SPI antisera. 3. Both seminoma and choriocarcinoma, and even embryonal rhabdomyosarcoma and malignant lymphoma disclosed positive reaction to anti-PAPP-A antisera.
오세창(SC Oh),염석호(SH Yeum),최완주(WJ Choi),박찬용(CY Park) 대한산부인과학회 1986 Obstetrics & Gynecology Science Vol.29 No.11
저자들은 국립의료원 산부인과에서 1983년 1월부터 12월까지 1년간 총 3예의 자궁 육종을 경험하였기에 간단한 문헌 고찰과 함께 보고하는 바이다 We have experienced 3 cases of leiomyosarcoma of uterus in 1983 and these cases are presented with relevant review of literature