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방풍통성산이 흰쥐의 Adjuvant 유발 관절염에 미치는 영향
엄관준 ( Kwan Joon Eom ),김지영 ( Ji Young Kim ),김순중 ( Soon Joong Kim ),서일복 ( Il Bok Seo ),정수현 ( Su Hyeon Jeong ) 한방재활의학과학회 2012 한방재활의학과학회지 Vol.22 No.2
Objectives :This study was carried out to investigate the effects of Bangpungtongseong-san(Fangfengtongsheng-san) treatment on the change of the adjuvant-induced arthritis in rats. Methods :Arthritis was induced by injection of complete Freund`s adjuvant(CFA, 0.1 ml) into the tail base of rats. Arthritic rats were divided into control(n=8) and treated(n=8) group. The control group was taken distilled water and the treated group, extracts of Bangpungtongseong-san(Fangfengtongsheng-san) by orally for 15 days. At the end of the experiment(28 days after CFA injection), gross and histopathological examinations on the articular structures of ankle joints were performed. The total number of white blood cells was measured by the ADVIA(automated blood cell counter, Bayer Co., Ireland). And also, tumor necrosis factor-α(TNF-α) and interleukin-1β(IL-1β) contents in paw exudate of rats were measured by enzyme-linked immunosorbent assay(ELISA) method. Results :1. Body weight(g) gain rate(%) of the treated group was increased significantly compared with control group at the 15th day after injection. 2. The thickness of ankle joints of the treated group was decreased significantly compared with the control group. 3. Histopathologically, finding of fibrous ankylosis of the treated group was decreased compared with the control group. 4. The total number of white blood cells in the treated group was decreased significantly compared with the control group. 5. TNF-α content and IL-1β content in paw exudate of the treated group were decreased significantly compared with the control group. Conclusions :On the basis of these results, we suggest that Bangpungtongseong-san(Fangfengtongsheng-san) has inhibiting effects on the progression of arthritis in CFA-induced arthritis model.
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요추 추간판 탈출증을 동반한 대퇴골두 무혈성 괴사 초기 진단 받은 환자를 대상으로 시행한 고관절 MST 및 한방 보존적 치료 치험 1례
백상현,김민우,엄관준,양승희,이승열,Baek, Sang-Hyun,Park, Min-Woo,Eom, Kwan-Joon,Yang, Seung-Hee,Lee, Seung-Yeol 척추신경추나의학회 2013 척추신경추나의학회지 Vol.8 No.2
Objectives : The Purpose of this study is to investigate the clinical application of conservative treatment including hip joint MST for lumbar HIVD(Herniated Intervertebral Disc) and early developed avascular necrosis of femur head. Methods : Patient is hospitalized at Dept. of Oriental Internal Medicine, Jaseng Oriental Medicine Hospital, diagnosed as lumbar HIVD(Herniated Intervertebral Disc) and early developed Avascular Necrosis of Femur Head and treated by herbal medicine, acupuncture, moxibustion and hip joint MST. This study was measured by NRS(Numeric Rating Scale), ODI(Oswestry Disability Index) and ROM(range of motion). Results : After conservative treatment, the patient's pain was controlled and NRS score was decreased. ODI and ROM also were improved. Conclusions : As seen in this one case, Oriental conservative treatment including hip joint MST has a positive effect to control pain with lumbar HIVD(Herniated Intervertebral Disc) and early developed avascular necrosis of femur head.
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