가감대황목단피탕(加減大黃牧丹皮湯)의 급성 췌장염 억제 효과

안재선,이해자,박은정,Ahn, Jae-Sun,Lee, Hai-Ja,Park, Eun-Jung 대한한방소아과학회 2006 대한한방소아과학회지 Vol.20 No.3

Objectives : In this study, we investigated the effects of Daehwangmokdanpitang-gagambang(DMG) on treatment for cholecystokinin-octapeptide(CCK)-induced acute pancreatitis(AP) in rats. Methods : Male Wistar rats weighing 200 to 250 g were divided into three groups. The first was normal untreated group, the second was in treatment with DMG group; DMG was administered orally, followed by 75 ${\mu}g/kg$ CCK subcutaneously three times, after 1, 3 and 5 h. This whole procedure was repeated for 5 days. The third was in treatment with saline group, the protocol was the same as in treatment group with DMG. We determined the pancreatic weight/body weight ratio, the levels of pancreatic HSP60, HSP72, ERK, p38 MAPK and the secretion of pro-inflammatory cytokines. Repeated CCK treatment resulted in the typical laboratory and morphological changes of experimentally induced pancreatitis. Results : DMG was significantly decreased the pancreatic weight/body weight ratio in CCKinduced AP and DMG increased HSP60 and HSP72 compared with CCK-induced AP. DMG suppressed ERK and p38 MAPK activation. Additionally, the secretion of $IL-1{\beta}$ and $TNF-{\alpha}$ and the levels of amylase and lipase were lower than that saline. Conclusions : DMG has an effect to treatment for CCK-induced AP.

의료기관 사무직 종사자의 조직공정성이 Followership과 조직시민행동에 미치는 영향 - LMX 조절효과 -

안재선 ( Jae-sun Ahn ),김종두 ( Jong-doo Kim ),김문중 ( Moon-jung Kim ) 한국병원경영학회 2018 병원경영학회지 Vol.23 No.2

Purposes: Based on samples of government officials who are working at public health centers, following research examines the Effect of Organizational Justice on the relationships between Followership and Organizational Citizenship Behavior and analyzes the moderating effect of Leader-Member Exchange. Methodology: For the methods, Sphericity verification, Exploratory factor analysis, Correlation analysis, Causal relation, Mediating effect of followership and Moderating Effect of The Leader-Member Exchange have been analyzed with SPSS 22.0 & AMOS 22.0 Ver. Findings: As a result of Correlation analysis, Predictive validity and Construct validity have meaningful effect. Also, In case of Path analysis, distributive justice and interactional justice have meaningful effect but procedural justice has no such effect on Followership. As a result of Mediated effect of followership analysis, distributive and interactional justice have positive impact on (Organizational and Interpersonal). As to the mediation effect of followership analysis, It is shown that distributive and Followership have meaningful effect on In-group, not Out-group. Lastly, It is shown that procedural justice and Followership have no meaningful effect on both In-group and Out-group. Practical Implications: For the implications, distributive justice and interactional justice have positive impact on Followership, while procedural justice has no such impact on Followership. Also, It also possibly has same result to the moderating effect of Leader-Member Exchange. Consequently, It is recognized that a fair process without a fair result cannot be valued. also, We can know that reward for procedural justice is evaluated to kind of negative.

내부지향 조직문화가 리더-구성원 교환관계와 협업3Cs에 미치는 영향 - 상사신뢰의 조절효과를 중심으로 -

안재선(Ahn, Jae Sun),김문중(Kim, Moon Jung) 글로벌경영학회 2016 글로벌경영학회지 Vol.13 No.2

본 연구는 급변하고 있는 공조직의 혁신을 강화하기 위한 협업방안을 모색하고자 경기도 내 45 개 보건소에 근무하는 공무원을 대상으로 실증 분석하였다. 연구의 목적은 내부지향 문화를 중심으로 리더-구성원 교환관계(LMX)와 협업(3Cs: 소통, 협력, 조정)과의 관계성과 상사신뢰가 LMX와 협업3Cs의 사이에서 조절효과가 존재하는지를 검증하는 것이다. 연구결과를 살펴보면 위계문화요인은 협업(3Cs)과 LMX에 대하여 모두 영향을 주지 않는 것으로 나타났다. 이는 위계적 질서가 중시되던 과거의 공조직의 문화가 변화되었다는 것을 알 수 있다. 반면, 집단문화에서는 협업(3Cs)과 LMX에서 높은 상관성이 있는 것으로 나타나서, 위계중심의 공조직문화가 변화되었다는 결과에 대한 반증으로 해석된다. 그리고 LMX의 매개효과와 상사 신뢰의 조절효과 역시 내부지향문화인 위계문화와 집단문화에 유의한 영향이 있는 것으로 나타났 다. 따라서 보건소에 근무하는 공무원 문화는 위계문화보다는 집단문화에 가까우며, 위계문화는 업무의 효율성 또는 효과성에 있어 무의미한 영향이 미치는 것을 알 수 있었다. 이러한 결과는 보건소라는 전문화된 공조직이 갖는 특수성에 기인한 것으로 판단하기는 어렵지만, 계층적 구조중 심의 공조직에 대한 전반적 변화가 반영된 것으로 해석되어지며, 향후 공조직 협업을 강화하려면 위계적, 계층적 문화가 아닌 집단적 문화가 보다 강조되어야 한다. 현대조직의 핵심요인인 리더 십과 관련하여 LMX와 상사신뢰는 조직운영의 필수적인 요소라는 것이 다시 한 번 확인되었다. 그러므로 조직효율성을 향상하려면 상사와 부하 간에 교환과정이 중요하며, 상사에 대한 신뢰강 화는 조직의 목표달성에 있어 긍정적인 효과가 가져올 것이다. This study was intended to public officials working in 45 health centers in Gyeonggi Province. The purpose of the study is to examine the relationships between Leader-Member Exchange(LMX) and Collaborative 3C; Communication, Cooperation, Coordination, focused on Inter-organizational Culture in an integrated perspective. As a result, It also examined the moderating effects on LMX trust and collaborative(3Cs) to trust in supervisors. Whereas group had given a positive effect on collaboration(3Cs) and LMX, Hierarchical culture has had a negative impact on collaboration (3Cs) and LMX. Mediating effects of LMX and Moderating role of trust in supervisors has also been demonstrated that it can be significant impact on the inter-organizational culture of hierarchy culture and group culture. Therefore, officials culture working in the health center was found to be close to the group culture rather than cultural hierarchy. It can be seen that the hierarchical culture is insignificant impact on the efficiency or effectiveness of the business. With regard to leadership, it is revalidated that trust in supervisors is essential factor to lead organization. Thus, leading organization member based on trust is expected to have a positive effect on the organization’s goal.

미국 보건부의 질 향상활동

김선민,김재선,박영희,안미라,김형호,은상준,박건희,Kim, Sun Mean,Kim, Jae Sun,Park, Younghee,Ahn, Mi Ra,Kim, Hyeong-Ho,Eun, Sang Jun,Park, Kunhee,Shin, Youngsoo 한국의료질향상학회 2007 한국의료질향상학회지 Vol.13 No.1

가미보중익기탕과 가미좌귀음의 폐 섬유화 치료 기전에 대한 예비 연구

이해자,신권성,안재선,Lee, Hai-Ja,Shin, Gwon-Sung,Ahn, Jae-Sun 대한한방소아과학회 2010 대한한방소아과학회지 Vol.24 No.1

Objectives In this study, we evaluated the therapeutic effects of Gami-Bojungikgitang and Gami-Jwagwieum for bleomycin-induced lung fibrosis in mice. Methods Extracted lyophilization, Gami-Bojungikgitang (96g) and Gami-Jwagwieum (118g) boiled, filtered, depressed, concentrated, and are obtained. They were divided into five groups: normal, group IA; Animal group treated with bleomycin observed on the 21th day, group IB; Animal group treated with bleomycin observed on the 42th day, group IIA; Animal group treated with bleomycin and Gami-Bojungikgitang. Gami-Jwagwieum observed on the 21th day, group IIB; Animal group treated with bleomycin and Gami-Bojungikgitang/Gami-Jwagwieum observed on the 42th day. Mice are used on the 42th day and as a result, bronchoalveolar lavages fluid is obtained. Counting total number of cells, different ratio of macrophage, lymphocyte, and neutrophil are established. Results In animal group treated with bleomycin and Gami-Bojungikgitang, total cell count decreased by 50% in 3 weeks compared to animal group with non-administrated Gami-Bojungikgitang. However, total cell count in 6 weeks increased compared to 3 weeks although total cell count still decreased compared to animal group with non-administrated Gami-Bojungikgitang. In the view of differential cell counts in bronchoalveolar lavages fluid in treatment group on 3 and 6 weeks, neutrophile was a few and lymphocyte decreased. In animal group treated with bleomycin and Gami-Jwagwieum, total cell count decreased by 50% in 3 and 6 weeks compared to animal group with non-administrated Gami-Jwagwieum. In the view of differential cell counts in bronchoalveolar lavages fluid in treatment group on 3 and 6 weeks, lymphocyte also decreased. Conclusions Gami-Bojungikgitang and especially Gami-Jwagwieum for bleomycin-induced lung fibrosis in mice were effective in total cell count and differential cell count.

초등학생의 건강기능식품 및 한약 복용 실태에 대한 연구

김미기,정지호,안재선,임정훈,안민섭,박진수,이해자,박은정,Kim, Mi-Ki,Jung, Ji-Ho,Ahn, Jae-Sun,Yim, Jung-Hoon,An, Min-Seop,Park, Jin-Su,Lee, Hai-Ja,Park, Eun-Jung 대한한방소아과학회 2009 대한한방소아과학회지 Vol.23 No.3

Objectives The purpose of this study is to get the basic information from patients how much they understood about their medication and also to know whether patients are making reasonable drug choice between Health Functional Foods and Herbal medicine. Methods 500 questionnaires were handed out to the parents of students in two elementary schools located in OO, Junlabukdo province. 421 questionnaires were completed to be evaluated. Results Among 421 subjects, 53.0% were female, and 47.0% were male. The percentages of the subjects consuming Health Functional Foods and herbal medicine were67.7% and 67.8%, respectively. Among those people who consumed Health Functional Food, 44.1% were using nutritional supplements, red ginseng or ginseng products (26.9%), chlorella products (11.5%), and plum extract products (7.7%). As for the reason to consume Health Functional Foods were varied, but 'in order to be healthy, although currently displaying no illness.'(43.0%) were the most responses among the given choices. On the other hand, the reason for consuming herbal medicine was 'In order to grow taller'(26.1%), 'In order to cure weak physical state frequently displaying common illnesses',(25.9%), and 'In order to cure diseases.'(23.3%). For the questions about effectiveness after consumption,the 69.9% subjects said that it seemed to be effected, and that % was slightly higher than that of subjects with consuming Health Functional Foods(64.4%). For question concerning preferences between Health Functional Foods and herbal medicine, 57.5% chose herbal medicine, and this percentage was higher than that of Health Functional Foods(42.5%).As for the reasons of additional consumption of the Health Functional Foods, subject answered as 'Easy to consume.'(41,6%), which was the most common among the subjects consuming Health Functional Foods. On other hand, the subjects of herbal medicine answered as that herbal medicine is 'more effective'(45.7%), and 'more trustworthy in preventing side-effects.'(40.3%). After consumption of the herbal medication, only 3.9% of the subjects consuming either Health Functional Foods or herbal medicine had side-effects. The most common side-effects were 'dermal reaction' which is normally caused by Health Functional Foods and 'indigestion' problems caused by herbal consumption. Conclusions According to the 421 subjects those involved in study, the percentages of consuming Health Functional Foods(67.7%) and herbal medicine(67.8%) were similar. The most commonly consumed products were a type of Health Functional Foods which were the nutrition-supplying products. Ginseng or red ginseng products were the next commonly used products. Health Functional Foods were commonly consumed for preventing illness and maintaining health rather than any other purpose. In contrary, herbal medicines were more commonly consumed for purposes such as for growth or treating certain type of disease. As a result of consumption, more than half of both subject replied as 'satisfied'. As for the side effects, dermal reaction was the most common problem for those with consuming Health Functional Foods, while indigestion was the most common side effect from the subjects with consuming herbal medicine.

요로감염이 동반된 소아 요로결석 환아 증례 보고

정지호,김미기,오지은,안재선,은선혜,박가영,이해자,박은정,Jung, Ji-Ho,Kim, Mi-Ki,Oh, Ji-Eun,Ahn, Jae-Sun,Eun, Seon-Hye,Park, Ga-Young,Lee, Hai-Ja,Park, Eun-Jung 대한한방소아과학회 2009 대한한방소아과학회지 Vol.23 No.3

Objectives A purpose of this study is to report a case study of a child with urolithiasis and urinary tract infections. Methods A four-year-old female had been taken Korean traditional medicine for two weeks, and clinical symptoms had been observed. Results Treating with Korean traditional medicine, symptoms of urolithiasis with urinary tract infections has been improved. Conclusions This study supports that Korean traditional medicine can be an effective means of treating internal medicine for urolithiasis with urinary tract infections, and further case studies are needed for more accurate results.

보건소직원의 감정노동과 조직신뢰, 조직몰입의 관계: 경기도 45개 보건소를 대상으로

박시현(Park Si Hyun),안재선(Ahn Jae Sun),최병열(Choi Byung Yul) 글로벌경영학회 2018 글로벌경영학회 학술대회 발표논문집 Vol.2018 No.2

연구의 목적은 공공부문의 감정노동자인 보건소에 근무하는 보건의료직 공무원을 대상으로 감 정노동의 표면행위와 내면행위가 조직신뢰와 조직몰입에 밀접한 영향관계가 있는지를 확인하고자 한다. 분석방법은 표본 추출은 경기도에 위치한 45개 보건소를 대상으로 하였으며, 표본의 수는 675부를 배포하여 324부를 사용하였으며, 요인분석, 상관관계분석, 각 경로별 인과관계와 매개효과 검증을 위해 IBM SPSS & AMOS 22.0 Ver 이용하여 분석하였다. 분석결과는 보건소에 근무하는 직원의 감정노동이 조직신뢰에 유의한 영향이 있으며, 조직신뢰가 조직몰입에 유의한 영향이 미치고, 감정노동 행위가 조직몰입에 유의한 영향이 있음이 증명되었다. [연구결과]는 감정노동에 있어 조직몰입에 부정적인 영향이 있는 선행연구가 많이 있으나 본 연구에서는 보건소직원의 감정노동이 조직신뢰와 조직몰입에 긍정적인 영향력이 있음을 알 수 있었다. 공공기관에 근무하는 공무원들 역시 감정노동을 하고 있다. 단순한 연구일수도 있겠으나 타 기관에 비해 보건소에 근무하는 공무원의 감정노동이 조직몰입에 긍정적인 영향이 있음을 확인시켜 준 결과를 제시하는 데 있어 의의를 찾을 수 있었다. 제언으로는 본 연구에서도 조직과 직무와 관련되어 있음을 알 수 있듯이 선행연구의 대부분은 감정노동의 결과변수로 태도와 행동에 초점을 두고 있다. 결과변수에 대한 다양하게 제시하고, 특히, 보건소 공무원의 인적자원에 대한 연구가 활발하게 진행되었으면 한다. The purpose of this study is to find out whether there is a close relationship between organizational trust and organizational commitment on the surface acting and deep acting of emotional labor for public official in public health centers. The analysis method was sampled from 45 public health centers located in Gyeonggi-do. The sample was distributed with 675 copies, and 324 copies were used. By using Structural Equation Model of statistical program SPSS & AMOS 22.0, primary factor and correlation has been analyzed. Validity of each variables’has been verified through primary factor and correlation analysis. As a result, it was proved that emotional labor had a significant effect on organizational trust, organizational trust had a significant influence on organizational commitment, and emotional labor had a significant influence on organizational commitment. This study suggests that emotional labor has a positive influence on organizational trust and organizational commitment, although there are many prior studies that have negative effects on organizational commitment in emotional labor. Public officials working in public institutions are also doing emotional labor. It is possible to find a meaningful result in confirming that the emotional labor of the public servants working at the public health center has a positive influence on organizational commitment. As suggested in the previous section, most of the previous researches focus on attitudes and behaviors as the outcome variables of emotional labor. The results of this study are as follows. I hope that the research on the human resources of public servants in public health centers will be actively conducted.

보건소 종사자의 감정노동과 직무소진이 조직유효성에 미치는 영향

권동연(Kone, Dong Youn),안재선(Ahn, Jae Sun) 한국보건간호학회 2016 韓國保健看護學會誌 Vol.30 No.3

소아 백혈병 환자에서 화학요법 후 간농양을 동반한 호중구감소성 소장결장염

박형석(Hyung Seok Park),이승현(Seung Hyun Lee),안병권(Byung Kwon Ahn),백승언(Sung Uhn Baek),박재선(Jae Sun Park) 대한외과학회 2004 Annals of Surgical Treatment and Research(ASRT) Vol.67 No.2