각종 간질환에서의 (肝疾患) 혈청 (血淸) High Density Lipoprotein - Cholesterol 의 변동

안성훈(Sung Hoon Ahn),박승국(Seung Kook Park),허정욱(Jung Wook Hur),이호찬(Ho Chan lee),김정철(Jung Chul Kim),정태호(Tai Ho Chung) 대한소화기학회 1984 대한소화기학회지 Vol.16 No.1

N/A In patients with liver disease, abnormalities of cholesterol metabolism has been suspected. Hence concentrations of cholesterol in whole serum, and cholesterol concentrations in the high density lipoprotein fraction of serum was measured after the precipitation of low density and very low density lipoproteins with sodium phosphotungstate-13Mg in l patients with liver cirrhosis, 10 patients with acute hepatitis, 10 patients with chronic hepatitis, 7 patients with hepatoma, 5 patients with obstructive jaundice, and 24 healthy control subjects. Total cholesterol concentrations in patients with hepatic cirrhosis were significantly lower than control, but in patients with chronic hepatitis, and obstructive jaundice, total cholesterol concentrations were slightly higher than control. High density lipoprotein cholesterol concentrations in various liver disease were significantly lower than control, and their ratios of high density lipoprotein cholesterol to total cholesterol were also significantly low.

간경변증환자에서 고농도 분지형 아미노산제제 투여후 혈중 아미노산과 간기능 검사상의 변화 - 일반 아미노산제제와 비교조사 -

안성훈 ( Sung Hoon Ahn ),박승국 ( Soong Kook Park ),박원대 ( Won Dae Park ),한승범 ( Seung Beum Han ),이수형 ( Soo Hyeong Lee ),허정욱 ( Jeug Wook Hur ) 대한소화기학회 1987 대한소화기학회지 Vol.19 No.1

N/A This study was done to compare the therapeutic effect of enriched branched chain amino acid (BCAA) infusion to regular amino acid infusion for the decompensated liver cirrhosis. Enriched BCAA solution (Pamisol) was given to 30 patients and regular amino acid solution (Salviamine) was given to 8 patints. The changes of plasma amino acid concentrations and liver profiles in before and 7 days after amino acid infusion daily 1,000 ml were compared. The results were as follow. 1) In the group of patients given enriched BCAA infusion, the plasma concentrations of valine, leucine, isoleucine (BCAA) increased (p<0.001), while the phenylalanine, tyrosine (aromatic amino acid: AAA) decreased (p<0.001). 2) In the group of patients given regular amino acid infusion, both BCAA and AAA concentrations increased (p+0.001). 3) In the group of patients given enriched BCAA infusion, total protein increased (p<=0.01), total bilirubin decreased (p<=0.01), prothrombin time shortened (p<0.05), and blood ammonia decreased (p< 0.01). 4) In the group of patients given regular amino acid infusion, only total protein increased (p < 0.01) but, bilirubin, prothromoin time and blood ammonia remained no significant changes. 5) The molar ratio of BCAA/AAA more improved in the enriched BCAA infusion than regular amino acid.

전이성 거세 저항 전립선암에서 Docetaxel 전신 화학요법의 최적의 횟수

안성훈(Sung Hoon Ahn),박승철(Seung Chol Park) 대한비뇨기종양학회 2013 대한비뇨기종양학회지 Vol.11 No.2

Metastatic prostate cancer is initially treated with androgen deprivation therapy, which induces rapid decrease in bone pain and decrease in serum prostate specific antigen level. However, most of cases with prostate cancer eventually progress to castration-resistant prostate cancer within a median of 18-24 months. Docetaxel-based systemic chemotherapy is now the standard treatment for CRPC, based on the results of 2 phase III studies. However, the optimal cycles of docetaxel-based systemic chemotherapy for CRPC has not been defined. Herein, we present two cases of castration-resistant prostate cancer treated by docetaxel-based systemic chemotherapy and reviewed recent literatures.

간 , 담도 및 췌장 : 한국 임산부에서의 황달에 관한 임상적 고찰

안성훈(Sung Hoon Ahn),박승국(Soong Kook Park),허정욱(Jung Wook Hur),강영우(Young Woo Kang),김경목(Kyung Mok Kim),한승범(Seung Bum Han) 대한소화기학회 1987 대한소화기학회지 Vol.19 No.2

N/A The jaundice in pregnancy generally is devided to peculiar liver disease and intercurrent disease to pregnancy. Its diagnosis and management are the matter of importance to clinician in view of complications of parturition, fetus and neonate. The clinical studies, however, on this field are scarce in this country. We analysed 19537 obstetric medical charts of Korean pregnant women admitted in the department of obstetrics & gynecology, Dongsan medical center in a period of ten years from January 1977 to December 1986. Serum bilirubins were checked in 1357 cases among the 19537 charts. The results were as follows; 1) The incidence of chemical jaundice in pregnancy was 3.5% (48 cases) in 1357 serum bilirubin checked. 2) The associated clinical conditions were 18 cases (37.5%) of toxemia at most, 6 cases (12.5%) of cholestasis of pregnancy, 3 cases (6.3%) of acute viral hepatitis and 18 cases (37.5%) of unknown cause of jaundice. 3) 15 cases (31.2%) of maternal postpartum hemorrhage, 5 cases (10.4%) of prematurity were considered as the complications of jaundice in pregnancy. The incidence of prematurity, fetal distress, perinatal mortality in jaundice group were statistically significant compared to that of Korean general group of pregnancy. For more detail study on jaundice in pregnancy we think prospective study including hepatitis marker, liver function test, liver biopsy and analysis of causes of jaunidce in pregnancy is necessary in all cases of pregnant women.

호산구성 (好酸球性) 위장염 (胃腸炎) 보고

안성훈(Sung Hoon Ahn),박승국(Seung Kook Park),허정욱(Jung Wook Hur),박성배(Seong Bae Park),허준영(Joon Young Huh),이택근(Taek Geun Lee) 대한소화기학회 1984 대한소화기학회지 Vol.16 No.1

Eosinophilic gastroenteritis is an uncommon disease charaterized by abdominal pain, vomiting, diarrhea, eosinophilia in peripheral blood and eosinophilic infiltration of gut. We experienced a case of eosinophilic gastroenteritis, which developed after ingestion of medicinal plant, Acanthopanax sessili florum, reported with review of literature.

탄자니아의 태양광 발전소와 통합된 전기 모빌리티 운영 시스템: 비전과 시범운행

이협승(Hyop-Seung Rhee),임혁순(Hyuck-Soon Im)프랭크 앤드류 마농기(Frank Andrew Manongi),신영인(Young-In Shin),송호원(Ho-Won Song),정우균(Woo-Kyun Jung),안성훈(Sung-Hoon Ahn) 적정기술학회 2021 적정기술학회지(Journal of Appropriate Technology) Vol.7 No.2

전 세계적인 지구온난화의 위협에 대응하고자 세계 각국은 신재생 에너지의 확산, 탄소 배출 감소 등을 추진하고 있다. 또한, UN의 SDGs에도 포함된 기후변화에 맞서기 위한 노력으로 글로벌 자동차 제조사들은 향후 10년내에 전기자동차로의 전면 전환을 추진하고 있다. 전기자동차는 탄소 배출 감소를 위한 유용한 수단이 될 수 있으나, 충전용 전기를 생산하는 단계에서 발생하는 탄소의 저감을 위해서는 친환경 신재생 에너지를 이용한 발전시스템이 요구된다. 본 연구에서는 아프리카 탄자니아에 설립된 태양광 발전소와 통합된 스마트 전기 모빌리티 운영 시스템에 대한 비전을 제안한다. 아두이노 컴퓨팅 장치를 기반으로 하는 스마트 모니터링 및 통신 기능을 적용하여 전기자동차 또는 전기 오토바이의 배터리 잔존용량, 배터리 상태, 위치, 속도, 고도, 도로 상태 등의 정보를 모니터링한다. 또한, 주변의 독립형 태양광 발전소 인프라와 통신하여 주행가능거리를 예측하고 충전 스케쥴 및 목적지까지의 경로 최적화를 수행하는 시나리오를 제시한다. 제안된 시스템의 구현 가능성은 전기 오토바이의 시험운행을 통해 검증되었다. 탄자니아에서 운영될 전기 모빌리티 시스템은 현지의 환경과 특성을 고려하여 친환경성, 경제성, 운용 용이성, 호환성 등의 요소가 고려되어야 한다. 본 연구에서 제안하는 스마트 전기 모빌리티 운영 시스템은 SDGs의 이행을 위한 중요한 기반이 될 수 있을 것이다. To respond to the threat of global warming, countries around the world are promoting the spread of renewable energy and reduction of carbon emissions. In accordance with the United Nation’s Sustainable Development Goal to combat climate change and its impacts, global automakers are pushing for a full transition to electric vehicles within the next 10 years. Electric vehicles can be a useful means for reducing carbon emissions, but in order to reduce carbon generated in the stage of producing electricity for charging, a power generation system using eco-friendly renewable energy is required. In this study, we propose a smart electric mobility operating system integrated with off-grid solar power plants established in Tanzania, Africa. By applying smart monitoring and communication functions based on Arduino-based computing devices, information such as remaining battery capacity, battery status, location, speed, altitude, and road conditions of an electric vehicle or electric motorcycle is monitored. In addition, we present a scenario that communicates with the surrounding independent solar power plant infrastructure to predict the drivable distance and optimize the charging schedule and route to the destination. The feasibility of the proposed system was verified through test runs of electric motorcycles. In considering local environmental characteristics in Tanzania for the operation of the electric mobility system, factors such as eco-friendliness, economic feasibility, ease of operation, and compatibility should be weighed. The smart electric mobility operating system proposed in this study can be an important basis for implementing the SDGs climate change response.

『비급천금요방(備急千金要方)』 침구편(鍼灸篇)으로 구성한 經穴 네트워크에 공간적 위치 변수가 미치는 영향

김민욱 ( Minuk Kim ),양승범 ( Seung Bum Yang ),안성훈 ( Seong Hoon Ahn ),손인철 ( In Chul Sohn ),김재효 ( Jae Hyo Kim ) 경락경혈학회 2012 Korean Journal of Acupuncture Vol.29 No.3

Objectives : Recently, network science is very popular topic in various scientific fields and many studies have reported that it gives meaningful results on studying characteristics of a complex system. In this study, based on network theory, we made acupoints network using data of combined acupoints which appeared at 『Beijiqianjinyaofang』. We focused to find out the distinctive roles of remote and local combinations on the network. Furthermore, we aimed to identify the possibility of numerical and quantitative application to acupuncture researches. Methods : Based on examples of combined acupoints in 『Beijiqianjinyaofang』, the network consisted of 291 nodes and 2,431 links. The spatial distances between combined acupoints were calculated by the human dummy model. We removed the links step by step for the three cases - remote, local, and random cases, and observed the characteristic changes by calculating path lengths, similarity indices, and clustering coefficients. Also cluster analysis was carried out. Results : The network had a small number of remote links, and a large number of local links. These two links had the distinct characteristics. Whereas the local links formed a cluster of nearby nodes, remote links played a role to increase the correlation between the clusters. Conclusions : These results suggest that acupoints network increases the connectivity between the distal part and the trunk of human body, and enables various combinations of the acupoints. This finding conclusively showed that mechanism of combined acupoints could be interpreted meaningfully by applying network theory in acupuncture researches.

유연 스킨을 적용한 모핑 날개 시스템에 관한 개념연구

박일경(Ill-kyung Park),김성준(Seung-jun Kim),김지수(Ji-soo Kim),임재훈(Jae-hoon Lim),안성훈(Seung-hoon Ahn) 대한기계학회 2012 대한기계학회 춘추학술대회 Vol.2012 No.2

흰쥐의 성별과 주령에 따른 족삼리(足三里) 위유(胃兪) 중완(中脘) 배혈(配穴) 시구(施灸)가 소장(小腸)수송능에 미치는 효과

유윤조 ( Yun Cho Yu ),권오상 ( O Sang Kwon ),오인균 ( In Kyun Oh ),양승범 ( Seung Bum Yang ),안성훈 ( Seong Hoon Ahn ),손인철 ( In Chul Sohn ),김재효 ( Jae Hyo Kim ) 경락경혈학회 2012 Korean Journal of Acupuncture Vol.29 No.4

Objetives: The aim of this study was to observe the effect of moxibustion at combined acupoints of ST36, BL21 and CV12 in rats with sex and age. Methods: This study measured small intestinal motility in rats. First, cauterize with moxa was applied 5 times to the ST36, BL21 and CV12 in rats classified by sex and age under enflurane anesthesia. And then same treatment is done to mached acupoints of ST36, BL21 and CV12. Results: In single acupoint groups, cauterizing with moxa on ST36 increased with 5, 7 weeks in female and all weeks in male. The BL21 group increased with 5, 6, 7 weeks in female, and only 5 weeks in male. The CV12 group showed increasing with 5, 6 weeks in female and only 7 weeks in male. In combined acupoints groups, the ST36+BL21 with 8 weeks in male, the ST36+CV12 with 5, 8 weeks in female and 5, 6, 8 weeks in male, the CV12+BL21 only with 5 weeks in female, the ST36+BL21+CV12 only with 5 weeks in female showed increasing, respectively. Conclusions: Although these differents according to the sex and age in rats do not have a established tendency, the results suggested that the effects of moxibustion are experimentally should be considered the sex and age of individual.

Vaccine Cold Chain Monitoring System Using IoT Vaccine Fridge for Developing Countries

유장현(Jang-Hyeon Lyu),박사무엘(Samuel Park),류종하(Jong-Ha Yu),왕심린(Xin-Lin Wang),임혁순(Hyuck-Soon Im),이협승(Hyop-Seung Rhee),안성훈(Sung-Hoon Ahn) 적정기술학회 2021 적정기술학회지(Journal of Appropriate Technology) Vol.7 No.1

콜드체인의 마지막 단계인 백신전달 과정에서 대부분 얼음을 넣은 단열컨테이너로 온도를 조절하며, 백신의 온도 조절이 적절하지 않아 낭비되는 백신의 양이 상당하다. 예방접종을 관리하고 운영하는데 온도 데이터가 중요하며, 본 연구에서는 실시간 백신전달 모니터링 시스템을 개발하였다. 휴대용 백신 냉장고의 온도, 위치 및 전력 소비 데이터를 수집하기 위해 문자(Short Message Service) 통신 방법을 사용하였고, 한국과 탄자니아(아루샤 및 킬리만자로 지역)에서 시스템을 테스트하였다. 개발된 백신 냉장고는 문자통신을 통해 데이터 손실없이 실시간으로 백신상태를 모니터링을 할 수 있었다. 백신의 상태 및 데이터는 클라우드 서버를 통해 웹 기반 유저 인터페이스에서 확인할 수 있었다. In the process of vaccine delivery and vaccination, temperature is mostly controlled by an insulated containers containingice. Moreover, amount of wasted vaccine is significant because the temperature of the vaccine is not properly controlled.A core challenge of vaccination is temperature data monitoring, since it is critical for managing and operating strategicalvaccination by health organizations. In this research, a real-time monitoring vaccine carrier system was developed. Temperature,location, and power consumption data of the vaccine carrier were monitored and working performances of thevaccine carrier were tested in both Korea and Tanzania (Arusha and Kilimanjaro regions). For both places, Short MessageService (SMS) communication method was used to send information of the carrier’s status. As a result, the monitoringsystem was able to transmit and receive real-time data of the vaccine carrier status while the vaccine carrier was tested.The vaccine status data can be accessed from any location through the cloud server and web-based user interface.