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한국산 실거리나무 열매로부터 새로운 축합형탄닌 화학구조결정 및 고혈압 예방효과
안봉전 ( An Bong Jeon ),이진태 ( Lee Jin Tae ),박정미 ( Park Jeong Mi ),곽재훈 ( Gwag Jae Hun ),이진영 ( Lee Jin Yeong ),박찬익 ( Park Chan Ig ),손준호 ( Son Jun Ho ),임흥열 ( Im Heung Yeol ) 대한본초학회 2003 大韓本草學會誌 Vol.18 No.4
N/A Objectives : The study was investigated decrease effiency for blood pressure of the pods of Caesalpinia sepiaria Methods : We isolated an novel compound as an angiotensin converting enzyrne(hrpertensive enzyme) inhibitor from the pods of Caedpinia sepiaria We measured inhibition rate of angiotensin converting enzyme. Results : We decided chemical structure of this new material, prodelphinidin B-3 3-0-gallate that combined with (+)-gallocatechin-3-O-gallate and (+)-gallocatechin by mechanical analysis. Effect of inhibition on the angiotensin converting enzyme was shown that B-ring, gallate compound in prodelphinidins, grown the effect of inhibition. Frodelphinidin B-3 3-0-gallate inhibited about 75.5% at 75 μmole, is shown a possibility that is used to industry. Conclusion : The pods of Chsalpinia sepiaria were expected functional agents for decreasing blood pressure at drug and food industry.
안봉전 ( Bong Jeun An ),이진태 ( Jin Tae Lee ),곽재훈 ( Jae Hoon Kwak ),박정미 ( Jung Mi Park ),이진영 ( Jin Young Lee ),박태순 ( Tae Soon Park ),손준호 ( Jun Ho Son ),이임식 ( Lim Sik Lee ),윤숭섭 ( Sung Seob Yun ) 대한본초학회 2004 大韓本草學會誌 Vol.19 No.2
N/A Objectives : The physiological activities of Pumpkin(Cucurbita moschata Duch) were investigated for industrial application. Methods : We were experimented radical scavenging effect, xanthine oxidase inhibition, tyrosinase inhibition and cytotoxicities effects of various cancer cell. Results : The results were obtained as follows Electron-donating ability(EDA) of the water extract of pumpkin was over 60% at concentration of 500 ppm, and ethanol extracts showed as high as 34% EDA. In both cell lines, water extract of pumpkin( Cucurbita moschata Duch) was higher than ethanol extract. Conclusion : The results indicated that water extract of pumpkin can be used as a natural ingredient with biological functions in cosmetic and food composition.
안봉전 ( An Bong Jeon ),이진태 ( Lee Jin Tae ),곽재훈 ( Gwag Jae Hun ),박정미 ( Park Jeong Mi ),이진영 ( Lee Jin Yeong ),손준호 ( Son Jun Ho ),배종호 ( Bae Jong Ho ),최청 ( Choe Cheong ) 한국응용생명화학회 2004 Applied Biological Chemistry (Appl Biol Chem) Vol.47 No.1
Biological activities and anticarcinogenicity of Korean Pear peel were investigated. Electron donating activity and superoxide dismutase (SOD)-like activity of fraction Ⅱ, Ⅲ were up to 80% and 50~60% at 50ppm, respectively. Inhibitory effects on xanthine oxidase were about 80% at 50ppm, breast adenocarcinoma was about 60% at 2,000ppm, higher Ⅲ than Ⅱ. Inhibitory effect on prostate adenocarcinoma was about 23% at 500ppm. In conclusion, Korean pear peel was expected to use as a functional material.
새로운 증점제 Purecell 첨가 시 샴푸와 크림의 안정화에 관한 연구
안봉전 ( Bong Jeun An ),이진영 ( Jin Young Lee ),손준호 ( Jun Ho Son ),이창언 ( Chang Eon Lee ),박태순 ( Tae Soon Park ),박정미 ( Jung Mi Park ),이인철 ( In Chul Lee ),배호정 ( Ho Jung Bae ),송미애 ( Mi Ae Song ),편정란 ( Jeong Ra 한국응용생명화학회 2006 Applied Biological Chemistry (Appl Biol Chem) Vol.49 No.1
한국산 지유로부터 새로운 Glucosyltransferase 및 Tyrosinase Inhibitor 분리
안봉전 ( An Bong Jeon ),이진태 ( Lee Jin Tae ),박정미 ( Park Jeong Mi ),곽재훈 ( Gwag Jae Hun ),이진영 ( Lee Jin Yeong ),박찬익 ( Park Chan Ig ),손준호 ( Son Jun Ho ),임흥열 ( Im Heung Yeol ) 대한본초학회 2003 大韓本草學會誌 Vol.18 No.4
N/A Objectives : The study was experimented anti-plaque and whitening efficiency of the roots of Sanquisorbae sfficinalis L. Methods : We identificated novel procyanidin structure established by thiolysis, desulfurization, tannase reaction, methylation and spectroscopic analysis, The physiological activity of anti-plaque and whitening efficiency was evaluated. Results : The chemical structure was identified for procyanidin B-3 3-0-gallate containing the dimeric flavan-&oh, gallate and molecular weight was 792[M-H]- by FAB-MS negative ion method. The inhibitory effect on the glucosyltransferase and tyrosinase activity was investigated, novel compound showed complete inhibition at 0.75mM on the glucosyltransferase and tyrosinase was inhibited about 50% at 1001.1M. Conclusion : The roots of Sanguisorbae @citmlis were expected functional agents for anti-plaque and whitening.