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        간장 ( 肝臟 ) · 담도 ( 膽道 ) 및 췌장 ( 膵臟 ) : HBeAg 보균자 , 정상성인 그리고 각종 간질환에서 혈청 Ferritin치에 관한 연구

        정남기(nam Ki Joung),심승식(Seung Sik Shim) 대한소화기학회 1991 대한소화기학회지 Vol.23 No.4

        N/A In order to compare serum ferritin levels in each groups, the serum ferritin and serum transaminase were measured in 38 normal adults, and 50 patients with HBeAg carriers, 253 patients of various liver diseases (31 patients with acute hepatitis, 80 patients with chronic hepatitis, 119 patients with liver cirrhosis, 23 patients with hepatoma) who were admitted to St. Columban hospital from January 1989 to December 1989. Then we evaluated the relationship of serum ferritin levels in each groups. The following results were obtained. 1) The serum ferritin levels in 38 normal adults were 225 +- 71.06 ng/ml, and 215.50 +- 63.26 ng/ml in HBeAg carriers, but there was no correlatin in two groups. 2) Ferritin levels in each disease groups were higher than normal adults except acute hepatitis and that of liver cirrhosis was significantly elevated (p<0.01). 3) There was no significant correlation in the levels of serum ferritin with the serum ALT activities. 4) Serum ALT was significantly elevated in HBsAg positive patients than HBsAg negative patients in each liver diseases. In conclusion, there was no significant elevation of serum ferritin levels in HBeAg carriers compared with non-carriers.

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        C 형 감염 바이러스 항체 양성자 75 명 역학조사

        천석배(Seog Bae Cheon),박창현(Chang Hyun Park),박찬웅(Chan Woong Park),강상구(Sang Gu Kang),최요안(Yo An Choi),김건형(Geon Hyung Kim),심승식(Seung Sik Shim),김지운(Ji Woon Kim) 대한내과학회 1995 대한내과학회지 Vol.49 No.4

        N/A Objectives: To determine the transmission route of hepatitis C virus in Korea, we studied 75, anti- HCV positive patients by epidemiologic questionnaire, retrospectively. Methods: 75patients were compared with 75healthy controls on the basis of the following factors : blood transfusion, acupuncture, admission, hepatitis patient within household(spouse andother's), extramarital intercourse, ear piercing, frequent alcohol drinking, frequent raw-fish ingestion, frequent shaving at barbershop, low socio-economic status, tattooing. Results: Compared with control group, the relative ratio(anti-HCV positive case/control case) of the history of blood transfusion was 2.4(p=0.275); acupuncture was 1A2 (p=0.383); admission was 1.83(p=0.001); spouse`s hepatitis was 13(p=0.003) (6.4% in male, 28.6% in female); hepatitis patient within household except spouse was 1.75(p=0.46) (17.0% in male, 35.7% in female); extramarital intercourse was 5.44 (p< 0.001); frequent alcohol drinking was 1.42 (p=0.515); frequent shaving at barbershop in male was 2.95(p=0.043); low status of the education or economic was 1.39 or 1.71, and tattooing were 5cases in only anti-HCV positive group, respectively. Conclusion: According to the results, hepatitis C virus infection was related to the histories of admission, spouses hepatitis, extramarital intercourse, frequent shaving at barber-shop, and tattooing, closely. Although the relationship was not siginficant, the histories of blood transfusion, acupunture, hepatitis patient within household except spouse, frequent alcohol drinking and low socioeconomic status in anti-HCV positive group were more than the control group. Therefore, it is necessary to make a close inspection of these suspicious potential risk factors. And also, every risk factor calls for the serologic examination, not by questionnaire, of the intrafamilial or contracked personal transmission, for the prospective study and for the strengthened test by RIHA or PCR.

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