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확장형 심근증에서 도플러 심초음파를 이용한 좌심실 구혈력 및 내인성 심실 부하역동의 평가
채창식(Chang Sig Chae),이연재(Youn Jae Lee),박정현(Jeong Hyun Park),조기정(Gi Jeong Cho),김환태(Hwan Tae Kim),신형규(Hyung Gyu Shin),김동수(Dong Soo Kim),이경순(Kyung Soon Lee) 대한내과학회 1994 대한내과학회지 Vol.46 No.3
N/A Background: Since the concept of peak aortic blood velocity and peak acceleration by Rushmer et al, doppler echocardiography based on the hemodynamic theory has developed as a new noninvasive measure for the evaluation of left ventricular systolic function during the ejection time. Method: The left ventricular ejection force over the acceleration time and the intrinsic component of the left ventricular load at peak acceleration, measured by pulsed wave doppler echocardiography, were compared in 10 patients with idiopathic dilated cardiomyopathy with 9 normal controls. Results: 1) The fractional shortening, peak aortic blood velocity, mean acceleration and ejection force over the acceleration time were significantly lower in the dilated cardiomyopathy group than control group (control vs DCM =33.88±4.75% vs 17.21±5.99%, p<0 001, respectively). 2) By the regressin in the % fractional shortening,, measurement of ejection force over the acceleration time was more beneficial than measurement of peak aortic blood velocity and mean acceleration in assessing the left venticulat systolic function(r=63, 0.49 and 0.55 respectively). 3) The left ventricular intrinsic wall stress showed no significant statistical difference between 2 groups, but intrinsic σm/total σm ratio was significantly lower in the dialated cardiomyopathy group than control group (control vs DCM = 4.36±1.889: vs 1 88% vs 1.84±0.88% p<0.005). Conclusion: The measurement of the ejection force over the acceleration time and the left ventricular intrinsic wall stress/total ventricular load ratio were beneficial in evaluating the ejection hemodynamics during the left ventricular systole.
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