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- 저자 : 신지섭(Ji-Seob Shin) (검색결과 4 건)
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방풍통성산(防風通聖散)의 급성 메스암페타민에 의한 보행성 행동량과 c-Fos발현에 대한 효과
신지섭,장은영,김단효,김상찬,김광중,양재하,Shin, Ji-Seob,Jang, Eun-Young,Kim, Dan-Hyo,Kim, Sang-Chan,Kim, Kwang-Joong,Yang, Chae-Ha 대한한의학방제학회 2011 大韓韓醫學方劑學會誌 Vol.19 No.2
Objectives : The BangPungTongSungSan(BPTSS) has been used as a therapeutic agent for cerebrovascular disease, cerebral hemorrhage, hypertension, diabetes and obesity in oriental medicine. The present study designed to investigate the effect of BPTSS on behavioral change and neuronal activation induced by acute methamphetamine(METH, 2 mg/kg, i.p.) in C57BL/6 mice. Methods : Mice received the oral administration of BPTTS(25, 50 and 100 mg/kg) 1 h prior to saline or METH administration. Locomotor activity was measured for 90 min using videotractking method and c-Fos expression, as marker of neuronal activation, was identified in a separate groups of mice by immunohistochemistry. Results and conclusions : Methamphetamine injection significantly increased locomotor activity and c-Fos expression in the nucleus accumbens and striatum. Interestingly, BPTTS(100 mg/kg) significantly suppressed locomotor activity and c-Fos expression in the nucleus accumbens and striatum by acute exposure to METH. These results suggest that BangPungTongSungSan may be effective in suppressing the reinforcing effect of methamphetamine by modulation neuronal activity.
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설문조사 분석을 활용한 제조업 작업자의 위험행동 요인 분석
신지섭(Ji-Seob Shin),이훈기(Hunggi Lee),유상우(Sangwoo Yoo),신동일(Dongil Shin) 한국가스학회 2021 한국가스학회지 Vol.25 No.2
제조업 작업자들에 대한 위험행동 요인의 분석은 효과적인 휴먼에러 예방과 효율적인 안전관리제도의 시스템화를 가능하게 한다. 본 연구는 작업자들의 작업심리, 작업환경, 작업일탈 요인이 위험행동의도에 미치는 영향과 이러한 위험행동의도가 위험행동에 미치는 영향의 관계를, 중소 제조업 중 제조가공업 작업자 80명을 대상으로, 설문조사를 중심으로 분석하였다. 결과를 살펴보면, 작업심리와 작업일탈은 위험행동의도에 영향을 미치는 것으로 나타났으나, 직무만족과 작업부하에 해당하는 작업환경요인은 위험행동의도에 영향을 미치지 않는 것으로 나타났다. 동료들과의 관계, 업무의 만족 내지는 불만족 정도, 작업자가 느끼는 직무의 중요성 정도와 많은 작업량을 소화하기 위한 시간의 촉박함 등이 의도적인 위험 작업 유발에는 영향을 미치지 않지만, 위험행동에는 영향을 미치는 것으로 나타나, 의도성이 결여된 상태에서 작업환경요인은 위험행동을 수반하는 것으로 나타났다. Analysis of risky behavior factors for workers in the manufacturing industry enables effective human error prevention and systemization of an efficient safety management system. This study examines the relationship between the effects of workers work psychology, work environment, and work deviation factors on risky behavior intentions and the effects of such risky behavior intentions on risky behaviors. Among the small and medium-sized manufacturing industries, the analysis was focused on a survey of 80 workers in the manufacturing and processing industry. Looking at the results, it was found that work psychology and work deviation had an effect on the intention of risky behavior, but the work environment factors corresponding to job satisfaction and workload did not affect the intention of risky behavior. The relationship with colleagues, the degree of satisfaction or dissatisfaction with the job, the degree of importance of the job that the worker feels, and the tightness of time to digest a large amount of work do not affect intentionally inducing dangerous work, but they do affect risky behavior. In the absence of intention, the work environment factor was found to accompany dangerous behavior.
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유전 및 육종 : 국내 듀록의 종돈장간의 교류현황과 유전능력평가에 미치는 효과
서재호 ( Jae Ho Seo ),신지섭 ( Ji Seob Shin ),노재광 ( Jae Kwang Noh ),송치은 ( Chi Eun Song ),도창희 ( Chang Hee Do ) 한국동물자원과학회(구 한국축산학회) 2011 한국축산학회지 Vol.53 No.5
The study was carried to identify the impact on nation-wide genetic evaluation and to obtain basic materials for the development of strategies in Swine Improvement Network Project(SINP). Data consisted of pedigree records of 235,511 and performance records of 70,747 for Duroc from 1987 to 2010 were collected by Korea Animal Improvement Association. Performance traits included three point back fat thickness(Shoulder, Belly, Waist), loin area, days to 90 kg and average daily gain. Exchange of genetic resources cross the breeding farms was not high, and furthermore the sizable farms which can accommodate genetic evaluation within the farm were scarce. Three data sets(individual farm evaluation: I, two sub-group evaluation: S, and whole eight farm evaluation: P) were used for genetic analysis. Genetic variances were larger in subordinate farms than in joiners farms for connectedness, and consequently the heritabilities were generally higher in subordinate farms than in joiner farms with I. The standard errors of heritability were small in the order of I, S and P. Estimated average inbreeding coefficients were 1.12%, 0.95% and 1.53% for joiner and subordinate group with S and population with P, respectively. The estimated correlations of breeding values with I and P were lowest. The correlations of breeding values with I and P for traits ranged 0.22 to 0.45 for moved parent animals and 0.24 to 0.72 for all animals. The results in the study suggest that nation-wide evaluation uses more pedigree information and improves accuracy. Furthermore SINP for connectedness could help to improve the accuracy of evaluation.
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