http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
이영필,이순실,박경호,신완균,손인자,이민화,이상복 한국병원약사회 1993 병원약사회지 Vol.10 No.4
Patient counseling and medication teaching was conducted on compliance and orientation to drug therapy for 278 headache patients from Apr. 1993 to Jul. 1993 by co-work of doctors and pharmacists. Counseling was conducted with medication teaching manual and drug sample and then it was recorded to currently medication history, adverse effects and counseling contents. In analysis of counseling contents, headache incidence was higher in female than male (71.6% : 28.4%) and highest on the fifties. The percentage of headache types of tension HA, migraine, mixed type HA was 76.1%, 13.5%, 10.8% respectively. 160 patients(66.1%) had been conducted compliance well. Adverse effects were appeared in the form drowsiness, GI trouble, dry mouth, weight gain, constipation.
임신시 Lithium의 약동학적 변화 : 증례보고 A Case Presentation
이현정,이정민,김호순,조남춘,신완균 한국병원약사회 1997 병원약사회지 Vol.14 No.1
Lithium carbonate is used to treat patients with manic and bipolar depressive. The drug requires therapeutic drug monitoring because it has narrow therapeutic window its pharmacokinetic parameters show large interpatient variation. The physiological changes which occur as a result of the pregnancy influence upon the disposition of lithium carbonate in the pregnancy women. Those changes associated with pregnancy include in bodyweight with expansion of bodywater, induction of cardiac output and volume of distribution and renal function changes with and almost doubling of renal plasma flow and an approximately increase in the glomerular filtration rate. Lithium is eliminated through renal excretion renal excretion only. It is not binding protein nor metabolized after absorption. Lithium clearance increases with the renal function changes associated with pregnancy. This case presentation reports the changes of lithium clearance with the twenty nine-year-old pregnant woman. Lithium clearance was estimated by Bayesian method with moning trough level. Lithium clearance which was 0.398㎖/min/㎏ before pregnancy rose to 0.749㎖/min/㎏ when she became pregnant and fell to 0.319㎖/min/㎏ when she had therapeutic abortion.