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신수경 ( Su Kyong Shin ),서연림 ( Yeon Lim Suh ),최원준 ( Won Jun Choi ),이순애 ( Soon Ae Lee ),이종학 ( Jong Hak Lee ),백원영 ( Won Young Paik ) 대한주산의학회 2002 大韓周産醫學會雜誌 Vol.13 No.3
일반적으로 성상세포종은 주로 20~40대에 나타나는 종양으로 두개강내 종양의 약 12%를 차지하나 악성이며 예후가 불량한 역형성 성상세포종은 흔하지 않다. 임신과 동반되는 성상세포종은 매우 드문 것으로 알려져 있어 국내외적으로 보고된 예가 매우 드물다. 저자들은 임신 34주 4일의 산모에서 좌측 전두엽 역형성 성상세포종을 진단하였으며 임신 38주 1일에 제왕절개 분만을 하였고 분만 후 2개월째에 부분 종양절제술을 시행하고 방사선 치료와 항암 치료를 시행한 1예를 경험하였기에 보고하는 바이다. Intracranial astrocytoma is often discovered in third-fifth decade and occupies about 12% of the intracranial tumor patients. The concurrence of tumors of the brain and pregnancy is uncommon, moreover, astrocytoma of the brain in term pregnancy is very rare. Generally, astrocytoma is divided into six subgroups. Among them anaplastic astrocytoma is thought to be a malignant brain tumor. In the management of patients with brain tumor complicating pregnancy, judgments with regard to the optimal time for neurologic studies and operation and the mode of delivery are frequently difficult and occasionally controversial. We experienced a case of anaplastic astrocytoma of left frontal lobe, which was diagnosed by MR imaging at the third trimester of pregnancy. We report the case with a brief review of literature.
t(1122)(q25q13.1) 균형전좌 부계에서 발생한 Partial Trisomy 22
이상희 ( Sang Hee Lee ),조현철 ( Hyun Chul Cho ),신수경 ( Su Kyong Shin ),이재익 ( Jae Ik Lee ),최원준 ( Won Jun Choi ),이순애 ( Soon Ae Lee ),이종학 ( Jong Hak Lee ),백원영 ( Won Young Paik ) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.9
Trisomy 22 is a frequent finding in spontaneous abortion. However, survival to term is tenuous. So far there have been about 85 cases of trisomy 22. Most of all cases, trisomy 22 was result of 3:1 meiotic segregation in the maternal 11;22 translocation carrier. These patients have a supernumerary, abnormal chromosome 22 [der(22)], in their chromosome constitution: 47, XX(or XY),+der(22),t(11q;22q). Affected children have a distinct phenotype with multiple anomalies and severe mental retardation. We now report a viable case of 47,XX,+der(22)t(11;22)(q25;q13.1) resulting from 3:1 segregation in paternal translocation.