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RISS 인기검색어
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- 저자 : 송태하(Tae-Ha Song) (검색결과 3 건)
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골수술용 압전형 초음파 의료기기 개발을 위한 유한요소해석 및 이의 실험적 검증
송태하,이중호,최종균,이희원,Song, Tae-Ha,Lee, Jung-Ho,Choi, Jong Kyun,Lee, Hee Won 대한의용생체공학회 2022 의공학회지 Vol.43 No.5
In this study, the optimal driving frequency was derived through finite element analysis (FEA) to optimize the developed piezoelectric ultrasonic medical devices(PUMD) for bone surgery. The core of the PUMD is the piezoelectric ceramic (PZT), which is a vibrator that generates vibration energy. The piezoelectric ceramic shows the maximum current value with respect to the input voltage at the resonance frequency, which generates the maximum mechanical vibration. In the past, various studies have been conducted related to the analysis of PUMD, but most of the research so far has been limited to free vibration analysis. However, in order to derive the accurate resonant frequency, the initial stress generated by bolt tightening in the bolt-clamped Langevin type transducer (BLT) must be considered. In this study, after designing a PUMD, the driving performance according to the bolt tightening value was analyzed through FEA, and this was experimentally verified. First, the resonance mode and frequency response were confirmed through modal and harmonic analysis at 20-40 kHz, which is known as the optimal driving frequency band of PUMD for bone surgery. In addition, the design of the PUMD was confirmed by checking the mechanical behavior of the tip and the piezoelectric ceramic at the resonant frequency. Consequentially, the characteristic evaluation was performed, and it was confirmed that the resonant frequency result derived through the FEA was reasonable. Through this study, we presented a more rational FEA method than before for BLT transducers. We expect that this will shorten the time and cost of developing a PUMD, and will enable the development of more stable and high-quality products.
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이식거부반응을 줄이기 위한 cyclosporine A 탑재형 약물전달체의 개발
송태하(Tae-Ha Song),장진아(Jinah Jang),심진형(Jin-Hyung Shim),조동우(Dong-Woo Cho) 대한기계학회 2013 대한기계학회 춘추학술대회 Vol.2013 No.12
Systemic administration of Cyclosporine A (CsA) is frequently associated with a number of side effects which restrict the use of effective dose of immunosuppressant drug. For the purpose of local and controlled delivery of CsA, scaffoldbased CsA delivery system was developed. CsA-Poly(lactic-co-glycolic) acid(PLGA) microspheres-loaded drug carriers were prepared using Multi-head Tissue/Organ Building System which is based on the 3D printing technique. Proinflammatory cytokine expressions, which are secreted by Concanavalin A activated spleen cells such as Interleukin-2, Interleukin-17 and Interferon-gamma were significantly decreased by acting of CsA-loaded drug carrier in-vitro. Human lung fibroblasts-seeded CsA-loaded drug carriers were subcutaneously implanted into the BALB/c mouse model. Infiltration of mononuclear cells and CD4+, CD8+ T-cell populations at the site of implantation were investigated by H&E staining and immunohistochemistry. Mononuclear cells infiltration and population of T-cells were significantly suppressed by CsA-loaded drug carrier in-vivo. These results show that the CsA-loaded drug carrier can be a promising solution for local and controlled delivery of CsA.
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MRI 영상 유도 수술 로봇을 위한 개선된 군집 분석 방법을 이용한 뇌종양 영역 검출 개발
김대관,차경래,승성민,정세미,최종균,노지형,박충환,송태하,Kim, DaeGwan,Cha, KyoungRae,Seung, SungMin,Jeong, Semi,Choi, JongKyun,Roh, JiHyoung,Park, ChungHwan,Song, Tae-Ha 대한의용생체공학회 2019 의공학회지 Vol.40 No.3
Brain tumor surgery may be difficult, but it is also incredibly important. The technological improvements for traditional brain tumor surgeries have always been a focus to improve the precision of surgery and release the potential of the technology in this important area of the body. The need for precision during brain tumor surgery has led to an increase in Robotic-assisted surgeries (RAS). One of the challenges to the widespread acceptance of RAS in the neurosurgery is to recognize invisible tumor accurately. Therefore, it is important to detect brain tumor size and location because surgeon tries to remove as much tumor as possible. In this paper, we proposed brain tumor detection procedures for MRI (Magnetic Resonance Imaging) system. A method of automatic brain tumor detection is needed to accurately target the location of the lesion during brain tumor surgery and to report the location and size of the lesion. In the qualitative assessment, the proposed method showed better results than those obtained with other brain tumor detection methods. Comparisons among all assessment criteria indicated that the proposed method was significantly superior to the threshold method with respect to all assessment criteria. The proposed method was effective for detecting brain tumor.
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