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RISS 인기검색어
- 검색키워드
- 저자 : 손호선(Ho Sun Son) (검색결과 3 건)
- 무료
- 기관 내 무료
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손호선(Ho Sun Son),고동혁(Dong Hyuk Ko),김향(Hyang Kim),이만호(Man Ho Lee),정을순(Eul Soon Chung),이상종(Sang Jong Lee),원남희(Nam Hee Won) 대한내과학회 1989 대한내과학회지 Vol.37 No.3
N/A Membranoproliferative glomerulonephritis (MPGN) with dense intramembranous deposits, so-called type II MPGN, is a subtype of idiopathic MPGN, and was described as a separate entity by Berger and Galle in 1963. It frequently occurs in older children and young adults and the clinical course is variable, but is generally progressive. The presenting feature is nephrotic syndrome in many patients, and proteinuria and hematuria are also seen frequently. Recently we experienced a case of type II MPGN which was proven by renal biopsy. A 14-year-old school boy was admitted to this hospital because of generatlized edema and hematuria which developed three weeks after an upper respiratory infection. The histopathologic findings showed a thickened capillary basement membrane with a tram-track appearance and epithelial crescent formation on light microscopy, and a characteristic rihbon-like appearance of the glomerular basement membrame with electron-dense deposits on electron microscopy. The patient received triple drug therapy including corticosteroid, dipyridamole and cyclophosphamide without improvement.
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이상종(Sang Jong Lee),이만호(Man Ho Lee),박영철(Young Chul Park),김명숙(Myung Sook Kim),서영주(Young Joo Suh),손호선(Ho Sun Son),임시영(Si Young Lym),송준호(Jun Ho Song) 대한소화기학회 1989 대한소화기학회지 Vol.21 No.1
Mesotheliomas are infrequently encountered tumors that arise from the surfaces of any mesothelial lined body cavity. They are found most often in the pleural cavity, less frequently in the peritioneal cavity, and much less frequer,tly in the pericardial cavity or arising from the tunica vaginalis. The tumors are most often malignant and usually are detected late in their course when they begin to interfere with organ fuction. Recently we experienced three cases with peritoneal mesothelioma who proved by laparoscopi biopsy. The first case had a five-month history of exhaustion, epigastric distress after meal and weight loss which was treated under the impression fo nephritis without improvement by LMD. After abdomial ultrasound and CT examination disclosed an irregular soft tissue mass in the omentum and per- itoneum associated with ascites, he received vincristin, doxorubicn and dacarbazine with transient improvement. The second case in a 74-year-old widow who had noted epigastric discomfort after meal for a few years, and recently increasing girth. Both abdominal ultrasound and computed tomogram showed an irregular soft tissue mass in the omentum, peritoneum and mesentery with a large amount of ascites. The latter patient had selected to receive only supportive therapy. The last case is a 53-year-old farmer who had suffered from abdominal discomfort for a few years. The ]aparoscope showed irregular sized tumor mass in the peritoneum, omentum and pelvic cavity, also there was ascites in the peritoneal cavity. He received chemotherapy including cycophosphamide vincrstin and adriamycin, but expired.
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몇가지 간질환에 있어 혈중 Neopterin 치의 의의
정을순(Eul Soon Chung),이상종(Sang Jong Lee),김향(Hyang Kim),손호선(Ho Sun Son),김병익(Byoung Ik Kim),백문철(Moon Chul Baek),이승세(Seung Se Lee) 대한소화기학회 1989 대한소화기학회지 Vol.21 No.2
N/A It was recently observed that the hyperimmune response in vitro as in vivo was always accompanied by high levels of neopterin. Indeed in vitro, the stimulation of lymphocytes or macrophages either with viral alloantigens or with chemically modified autologous cells induces a remarkable release of this substance by means of the gamma interferon induction. In the viral infections the increased levels of neopterin could be due to the direct stimulation by the virus on the nucleic acid of the hosts cell (wacher et al ; 1957) Our aim was to verify if during fatty liver or hepatitis, and in cirrhosis of the liver there could be significant variation of serum neopterin levels. We studied 75 patients suffering from hepatic diseases, ranging between 22 and 84 year (mean age 48.96+14.2) and 20 healthy controls homogeneous for sex and age to our patients. The mean values of serum neopterin were 2.17+0.94 ng/ml in patients and 1.59+0.35 ng/ml in the control group. These data was correlated with the mean values of both SGOT and SGPT that were 152.25+278.61 IU/L, 204+405.94 IU/ respectively, and the statistical study showed positive but low correlation coefficient (SGOT:r = 0.28, p<0.05; SGPT:r = 0.30, p<0,05). There was no significant difference of serum neopterin levels between patients with fatty liver and control group (t = 1.057, p>0.05). However, the statistical study showed a significant difference between hepatitis, cirhosis of the liver and the normal control group(p<0.05). Serum neopterin levels and triglycerides were shown to be the best variables for discriminating between the hepatitis and fatty liver patients, neopterin being the more specific of the two. No significant correlation of serum neopterin levels between B hepatitis and non B hepatopathies could be found.
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