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      • SCOPUSKCI등재

        Ehlers - Danlos 증후군

        주용진,최성문,최영자,성호석 ( Yoing Jin Joo,Sung Moon Choi,Young Ja Choi,Ho Suk Sung ) 대한피부과학회 1990 대한피부과학회지 Vol.28 No.5

        A Case of Ehlers-Danlos syndrome Yoing Jin Joo, M.D., Sung Moon Choi, M.D., Young Ja Choi*, M.D., Ho Suk Sung, M.D. Department of Dermatology, Clooego of Medicine, Inje University, Pusan, Korea We presented a case of Ehlers-Danlos syndrome in a 25-year old female, who had hyperextensibility of skin, skin fragility, cigarette paper-like atrophic scar, joint hyperextensibility and skeletal abnormality of scoliosis since birth. There was no family history. Microscopic and electron microscopic examinations of the skin biopsy specimens from normal appearing skin on the forearm and the site of subcutaneous nodule was compatible with finding of Ehlers-Danlos syndrome. Although the manifestations of this case including marked extensibility of skin, joint, skin fraility and atrophic scar might be in accord with type Ⅰ(gravis) Ehlers-Danlos syndrome, skeletal abnormality of scoliosis did not correspond to this type, but to type Ⅳ(hydroxylysine deficient) Ehlers-Danlos syndrome. We consider this case as a type Ⅳ Ehlers-Danlos syndrome.

      • SCOPUSKCI등재

        조직구성 세포탐식성 지방층염

        박필성(Pill Sung Park),주용진(Yoing Jin Joo),최영자(Young Ja Choi),성호석(Ho Suk Sung) 대한피부과학회 1989 대한피부과학회지 Vol.27 No.6

        We report a case of histiocytic cytophagic panniculitis in a 5-year-old male. The patient has complained of multiple erythematous indurated palques with tenderness on the lower abdomen, periocular areas, left forearm and both thighs associated with high fever for 45 days. Hepatosplenomegaly and enlarged lymph nodes were found. Laboratory data revealed pancytopenia, elevation of liver enzymes and prolon gation of PT and PTT. Histopathologic findings of subcutaneous plaque taken from the left forenrm showed lobular panniculitis with fat necrosis and some phagocytic histiocytes containing erythrocytes, leukocytes, lymphocytes and nuclear debris, that had the appearance of bean bag. There found no atypical histiocytic infiltrations or cellular pleomorphism.

      • 다형홍반의 병리조직학적 고찰

        주용진,최영자,성호석 인제대학교 1990 仁濟醫學 Vol.11 No.3

        임상 및 병리조직학적으로 확진된 다형홍반 43례(남자 22례, 여자 21례)를 대상으로 임상형에 따른 병리조직학적 소견을 비교 검토하였다. 임상적으로는 반, 구진형, 수포형, Stevens-Johnson증후군으로 분류하였으며, 병리조직학적 소견은 표피형, 진피형, 혼합형 등으로 나누어 관찰하였는데, 반구진형에서는 표피형 11.1%, 진피형 22.2%, 혼합형이 66.7%였고, 수포형에서는 표피형 30.8%, 진피형 7.7%, 혼합형이 61.5%였으며, Stevens-Johnson 증후군에서는 모두 표피형이었다. 각질세포의 광범위한 괴사는 표피형에서보다 수포형과 Stevens-Johnson 증후군에서 훨씬 많이 관찰되었다. It is well documented that erythema multiforme presents a varied histopathologic pictures analogous to its clinical multiformity. In order to assess the histopalhologic findings of erythema multiforme according to the clinical types, we analyzed microscopic features of biopsy specimens obtained from 43 patients with erythema multiforme, comprising 22 males & 21 females, aging from 7 to 64 years. The results obtained were as follows; 1.Clinically there were 27 cases of maculopapular type(62.8%), 13 cases of vesicobullous type(30.2%) & 3 cases of Stevens-Johnson syndrome(7.0%) in this series. 2.Histopathologically thre were 26 cases of mixed type of erythema multiforme(60.5%), 10 cases of epidermal type(232%) and 7 cases of dermal type(16.3%) in this series. 3.As for the histological rape of distribution, mixed type of erythema multiforme was most frequently observed in maculopapular & vesicobullous type while epidermal type observed in all 3 cases of Stevens-Johnson syndrome 4.Extensive epidermal necrosis was more likely seen in Stevens Johnson syndrome & in vesicobullous type than in maculopapular type.

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