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최영민(Young Min Choi),구승엽(Seung Yup Ku),채호진(Ho Jin Chae),정현정(Hyeon Jeong Jeong),김기동(Ki Dong Kim),김훈(Hoon Kim),김정화(Jeong Hwa Kim),김태준(Tai June Kim),정현훈(Hyun Hoon Chung),서창식(Chang Suk Suh),김석현(Seok Hyun K 대한산부인과학회 2001 Obstetrics & Gynecology Science Vol.44 No.10
N/A Objective : To identify the causes of primary amenorrhea in the Korean population. Methods : We reviewed the available medical records of the 100 patients who had visited the Department of Obstetrics and Gynecology at Seoul National University Hospital with the complaint of primary amenorrhea and examined their karyotypes between January 1989 and December 2000. Review of history, physical examination, laboratory findings, imaging studies, and operative findings was done, when needed. Results : The mean age at diagnosis was 25.1±6.1 (mean±S.D.) years of age, ranged 14 to 40. Mllerian agenesis was the most common cause (40.0%), followed by primary ovarian failure (33.0%), and then followed by hypothalamic-pituitary failure (12.0%). Androgen insensitivity syndrome and Swyer syndrome were found in four patients (4.0%), respectively. Conclusion : This study shows that the common cases of primary amenorrhea in Korean women are Mllerian agenesis, primary ovarian failure and hypothalamic-pituitary failure.