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0.5% Timolol과 2% Dorzolamide의 병용투여군과 cosopt®단독 투여군에서의 안압 하강 효과비교
서정성,최광주,나경수,조남수 조선대학교 부설 의학연구소 2002 The Medical Journal of Chosun University Vol.27 No.1
ackground and Objective: This study was designed to compare the IOP decreasing effect between the IOP decreasing effect of patients who were treated with 0.5% Timolol and 2% of Dorzolamide and that of patients who were treated with Cosopt® only being the patients who couldn't be controlled by Timolol adequately. Materials and Method: Twenty eight open angle glaucoma patients, 40 eyes, who weren't able to reach desirable IOP when treated with 0.5% Timolol, were tested. The patients were divided into two groups. In group A 13 patients, 20 eyes, were treated with Timolol and 2% Dorzolamide. In group B 15 patients, 20 eyes, were treated with Cosopt® only. The IOP and side effects were recorded after The 1st week, the 1st month and the 3rd month. Results: After 3 months, the IOP in group A was decreased by 20.5% (4.0mmHg) from 19.5mmHg to 15.5mmHg and the IOP in group B was decreased by 23.7% (4.7mmHg) from 19.8mmHg to 15.1mmHg. There was no statistical significance between the two groups. Conclusion Cosopt® has a similar IOP decreasing effect with that of 0.5% Timolol and 2% Dorzolamide combined. It may increase adaptation of patients by decreasing the number of dispensions.
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EYEMAX free RGP 콘택트렌즈의 임상성능에 대한 유용성 평가
유근창,서정성 대한시과학회 2010 대한시과학회지 Vol.12 No.1
목적: 본 연구는 안정피로 개선용 EYEMAX free(Happy vision, Korea) RGP 렌즈에 대한 원거리 및 근거리 시력보정효과, 렌즈착용 후 증상, 안정피로에 대한 피험자의 만족도 등의 임상성능에 대한 유용성을 평가하고자 하였다. 방법: 18세~43세 남·여 35(70안)명을 대상으로 EYEMAX free RGP 렌즈를 착용 한 달 후 근거리시력과 원거리시력, 렌즈착용 증상, 렌즈 적응도, 안정피로 개선효과에 대하여 조사하였다. 결과: 피검사자의 원거리 및 근거리 안경교정시력이 각각 0.97±0.08D, 1.04±0.19D이었으나, 렌즈 착용 한 달 후 원거리 및 근거리 교정시력은 각각 1.19±0.16D, 1.30±0.13D로 안경교정시력 보다 높게 나타났다. 렌즈착용 1개월 후 자각증상의 빈도가 높은 증상은 건조감과 이물감이었으며, 피험자의 렌즈 적응도는 쉬운 적응이 23명, 보통의 적응이 9명이었으며, 3명만 적응이 어렵다고 하였다. 렌즈착용에 대한 6개 항목 만족도의 유효성 평가에서 평가점수가 0~2점의 피험자 수의 백분율이 66.7% 이상으로 유효성이 있는 것으로 나타났다. 결론: 전체 피험자 수에 대한 유효성 평가에서 EYEMAX free RGP 렌즈는 교정 후 원거리 및 근거리 시력보정 효과에 대한 피험자 수의 백분율이 97.2%로 나타나 시력교정에 대한 유효성이 있으며, 안정피로 개선에 대한 만족도가 높은 기능성 RGP 렌즈라고 생각된다. Purpose: To analyze clinical performance of Auto ref-Keratometer(ARK-510A: NIDEK Co.) and Corneal Analyzer (OPD-SCANⅡ: NIDEK Co.). Method: 33 subjects(mean age of 27.42±3.3) who have no ocular disease were recruited. Automatic refraction(ARK-510A: NIDEK Co.), OPD-SCAN Ⅱ: NIDEK Co.) and subjective refraction were measured twice with one day interval at the least. The values were converted to J vector(M, J0, J45) in order to evaluate reliability and accuracy. Result: Mean difference and 95% limit of agreement of test-retest by ARK-510A were M=-0.027±0.405D(-0.821~0.767D), J0=0.020±0.138D(-0.250~0.290D), J45=-0.002±0.097D(-0.192~ 0.188D) and M=0.094±0.495D(-0.876~1.064D), J0=0.026±0.138D(-0.244~0.300D), J45=0.002±0.093D(-0.180~0.184D) by OPD-SCANⅡ respectively. Reliability coefficient of ARK-510A was M=0.992, J0=0.976, J45=0.932, and that of OPD-SCANⅡ was M=0.989, J0=0.967, J45=0.903. Mean difference and 95% limit of agreement between measurements of subjective refraction and ARK-510A was M=0.258±0.600D(-0.918~1.434D), J0=-0.088±0.116D(-0.315~0.139D), J45=-0.009±0.120 (-0.244~0.226D) and those between subjective refraction and OPD-SCANⅡ was M=0.381±0.624D(-0.842~1.604D), J0=0.022±0.098D(-0.170~0.214D), J45=0.001±0.108D(-0.210~0.212D). Accuracy of two instrument was different at M(p=0.006) and J0(p=0.000) significantly. Conclusion: Automatic refractometer (ARK-510A) was showed better accuracy and repeatability than those of corneal analyzer(OPD-SCANⅡ). It is considered that corneal analyser can be used clinically to measure refractive error.
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