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攝取油脂의 種類가 高콜레스테롤食餌 흰쥐의 血淸 및 肝臟의 脂質成分에 미치는 影響 - 들깨기름과 말쥐치기름을 中心으로 -
정승용(Seung-Yong Chung),서맹희(Maeng-Hee Seo),박필숙(Pil-Sook Park),강보순(Jin-Soon Kang),강정옥(Jeong-Ock Kang) 한국식품영양과학회 1986 한국식품영양과학회지 Vol.15 No.1
w-3계 linolenic acid가 풍부한 들깨기름 및 EPA와 DHA가 함유된 말쥐치기름의 혈청 및 간장의 지질성분에 마치는 영향을 구명하기 위해 지방산조성이 다른 몇가지 유지를 고콜레스테롤 식이 흰쥐에 식이하므로서 혈청 및 간장중의 지질농도에 미치는 영향을 비교 실험하여 다음과 같은 결과를 얻었다.<br/> 1. 사료섭취량과 증체량은 전 시험군간에 있어 별다른 차이가 없었다.<br/> 2. 혈청의총 cholesterol농도는 soybean oil perilla oil및 file fish oil 식이군이 대조군에 비해 유의적으로 낮았다.<br/> HDL-cholesterol 농도는 file fish oil 식이군이 가장 높았으며, perilla oil 식이군도 약간의 상승효과가 있었다.<br/> 총 cholesterol에 대한 HDL-cholesterol의 비율은 file fish oil식이군이 가장 높았다.<br/> 3. 간장의 총 cholesterol농도는 전 시험군간에 유의적인 차이는 없으나 file fish oil 및 perilla oil 식이군에서 약간 낮은 경향이었다.<br/> 4. 혈청의 triglyceride농도는 soybean oil 및 perilla oil식이군이 대조군에 비해 유의적으로 낮았다.<br/> phospholipid의 농도는 file fish oil식이군이 가장 낮았으며, soybean oil 및 perilla oil식이군에서도 대조군에 비해 유의적으로 낮았다.<br/> 5. 간장중의 triglyceride및 phospholipid의 농도는 전시험군간에 유의적인 차이는 없으나, perilla oil식이군이 약간 낮은 경향이었다.<br/> 이상의 결과로 미루어 보아 perilla oil 및 file fish oil은 혈청의 총 cholesterol, 및 phospholipid의 농도저하 효과가 다소 있는 것으로 사려된다. In order to investigate the effect of file fish oil and perilla oil on lipid components in serum and liver of rats on hypercholesterolemic diet, concentrations of total cholesterol, triglyceride and phospholipid in serum and liver were measured along with high density lipoprotein cholesterol concentration of the serum. Body weight gain and amount of food intake did not differ significantly among different dietary groups. Concentration of total-cholesterol in serum was significantly lower with 5% lard+5% soybean oil, 5% lard+5% perilla oil and 5% lard+5% file fish oil diets than with 10% lard diet. High density lipoprotein cholesterol concentration was highest in 5% lard+5% file fish oil group. Ratio of high density lipoprotein cholesterol to total cholesterol was highest in 5% lard +5% file fish oil group. Concentrations of total cholesterol in liver were not significantly different among all groups, but were slightly low in 5% lard+5% file fish oil and 5% lard+5% perilla oil groups. Concentration of serum triglyceride was significantly lower in 5% lard+5% soybean oil and 5% lard+5% perilla oil groups compared with 10% lard group. Concentration of serum phospholipid was lowest in rats on 5% lard+5% file fish oil diet and was lower in 5% lard+5% soybean oil and 5% lard +5% perilla oil groups than in 10% lard group.<br/> Concentration of triglyceride and phospholipid in liver were not significantly different among all groups. but tended to be relatively low in rats on 5% lard+5% perilla oil diet, In conclusion, the results suggest that perilla oil and file fish oil have depressing effects on serum levels of total cholesterol, triglyceride and phospholipid.
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말쥐치기름 및 들깨기름의 攝取가 高콜레스테롤 食餌 흰쥐의 血淸 및 肝臟의 脂質成分에 미치는 影響
鄭承鏞,朴畢淑,徐孟姬,姜晋順,禹靜淑 慶尙大學校 1985 論文集 Vol.24 No.1
Hypercholesterolemic male rats of Sprague Dawley, divided into six groups, were fed for 3 weeks with the diets containing several different oils of 10,0, the mixtures of 5% perilla oil and 5% other oils. The concentration of the lipid peroxide, T-cholesterol, phospholipid and triglyceride in the serum and liver were measured along with the HDL-cholesterol concentration of the serum. The results were as follows: 1. The concentration of LPO in the serum of the rats fed with lO% perilla oil, with 5% perilla oil+5% lard and with 5% perilla oil+5% file fish oil was higher than those with any other oils. The concentration of that was significantaly high in the liver of the rats fed with 10% perilia oil, while it was considerably low with 10% olive oil. 2. The concentration of T-cholesterol in the serum of the rats fed with 10% perilla oil, with 10% file fish oil and with 5% perilla oil+5% file fish oil was lower than those with any other oils. 3. The concentration of HDL-cholesterol was low in the serum of the rats fed with 10% perilla oil, while it was high with 5% perilla oil+5% file fish oil and with 10% file fish oil. The concen tration of that for the T-cholesterol in the serum of the rats fed with 10% file fish oil and with 5% perilla oil+5% file fish oil was much higher than those with any other oils. 4. The concentration of T-cholesterol in the liver of the rats fed with 10% perilla oil was high, while it was low with 10f file fish oil and with any other oils. 5. The concentration of PL and TG in the serum of the rats fed with 10% perilla oil and with 10% file fish oil was lower than those with any other oils, but it was lower in the liver of the rats fed with 10% perilla oil than the mixtures of perilla oil and with 10% file fish oil.
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