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리튬에 의해 동시에 발병된 미소 변화 신질환 및 만성 세뇨관 간질성 신염
하혜정 ( Ha Hye Jeong ),정은영 ( Jeong Eun Yeong ),백주은 ( Baeg Ju Eun ),김현정 ( Kim Hyeon Jeong ),이경원 ( Lee Gyeong Won ),양중일 ( Yang Jung Il ),박동준 ( Park Dong Jun ),장세호 ( Jang Se Ho ) 대한신장학회 2004 Kidney Research and Clinical Practice Vol.23 No.3
Lithium is commonly employed in the treatment of bipolar disorders. The commonly reported nephrotoxic effects of lithium therapy are nephrogenic diabetes insipidus and chronic tubulointerstitial nephropathy with little or no proteinuria. Mild proteinuria is a common manifestation of most renal injuries including nephrotoxicity by lithium. But nephrotic syndrome related with lithium therapy is very rare and only one case of membranous glomenilonephritis has been reported in Korea by this time. We report a lithium toxicity case manifested by nephrotic syndrome, nephrogenic diabetes inspidus and chronic renal insufficiency in a 4-year-old man who had been taking lithium for 13 years for bipolar disorder. Kidney pathology showed minimal change disease and chronic tubulointerstitial nephritis which can be seen in chronic lithium toxicity. Polyuria and massive proteinuria disappeared with the withdrawal of lithium. Renal function was gradually improved but not to norma range. Careful and regular monitoring an the renal function in all patients on lithium treatment will be needed. (Korean J Nephrol 2004;23(3) :500-504)
지속성외래복막투석 환자에서 발생한 Trichosporon beigelii 복막염
양중일 ( Yang Jung Il ),김미애 ( Kim Mi Ae ),정은영 ( Jeong Eun Yeong ),백주은 ( Baeg Ju Eun ),하혜정 ( Ha Hye Jeong ),김현정 ( Kim Hyeon Jeong ),박동준 ( Park Dong Jun ),장세호 ( Jang Se Ho ),전은실 ( Jeon Eun Sil ) 대한신장학회 2004 Kidney Research and Clinical Practice Vol.23 No.3
Fungal peritonitis is one of the leading causes of patients dropout from continuous ambluatory peritoneal dialysis (CAPD) therapy. Although the most causative agents of peritonits associated with CAPD are bacteria, fungi are implicated in up to 10% of cases. The most common organism of fungal peritonitis is Candida specises, but Trichosporon beigelii was reported as a rare causative agent of fungal peritonitis. We experienced a case of CAPD peritonitis by Trichosporon beigelii, which was treated with CAPD catheter removal, and antifungal agents with amphotericin B and fluconazole. Thus, we report our experience of CAPD peritonitis caused by Trichosporon beigelli and review of the literature. (Korean J Nephrol 2004;23(3):518-522)