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Klinefelter 씨 증후군과 연관된 원발성 종격동 생식세포암 1 예
서창인(Chang In Suh),배현주(Hyun Jue Bae),서철원(Cheol Won Suh),방영주(Yung Jue Bang),김노경(Noe Kyeong Kim) 대한내과학회 1989 대한내과학회지 Vol.36 No.4
N/A Klinefelter's syndrome is the most common cause of primary testicular failure and is defined by the spectrum of phenotypic features resulting from a sex chromosome complement that includes 2 or more X chromosomes and 1 or more X chromosomes. Several reports suggest that patients with klinefelter's syndrome are predisposed to the development of a nonseminomatous germ cell tumor in the mediastinum, We recently experienced a 26-year-old man with klinefelter's syndrome and primary mediastinal embryonal cell carcinoma, who was treated with combination chemotherapy and resection of the residual tumor.
급성백혈병의 관해수도시 trimethoprim sulfamethoxazole 의 간염예방효과에 관한 연구
최강원(Kang Won Choe),우준희(Jun Hee Woo),방영주(Yung Jue Bang),배현주(Hyun Joo Bae),서철원(Cheol Won Suh),김시영(Si Young Kim),박선양(Seon Yang Park),김병국(Byoung Kook Kim),김노경(Noe Kyeong Kim),김승택(Seung Taik Kim) 대한내과학회 1988 대한내과학회지 Vol.35 No.1
N/A Fifty patients with acute leukemia were studied during remission induction treatment in a prospectively radnomized trial to assess the effect of prophylactic trimethoprim/sulfamethoxazole on infection and fever rate. Twenty-three patients randomly received two single-strength trimethoprim/sulfamethoxazole tablets twice daily and twenty-seven patients did not receive any drugs. There were no significant differences in the duration of granulocytopenia, number of febrile days, or use of parenteral antibiotics. But trimethorpim/sulfamefhoxazole prophylaxis resulted in a reduced incidence of microbiologically documented infections (8 versus eighteen; p<0.05). This was mainly the result of a reduction in the episodes of bacteremia in the treatment group as compared with the contirol group. The number of patients without fever in the treatment group was eight compared to only 2 in the control group (p<0.05). Thus, trimethoprim/sulfamethoxazole prophylaxis during granulocytopenia reduced the incidence of microbiologically docummented infection and had more patients afebrile.
한진석,이동호,김수태,이정상,이현순,김성권,강윤구,김노경,방영주,배현주 대한내과학회 1987 대한내과학회지 Vol.34 No.1
In Korea, nine cases of Kaposi's sarcoma has been reported until now. We experienced 2 cases of renal transplant-associated Kaposi's sarcoma. The first case was a 56-year-old Korean man who had received cyclosporine and prednisone as immunosuppressant agent, and Kaposi's sarcoma developed 3 months after renal transplantation with multipe skin nodule, right palatine tonsilar nodule, and multiple pulmonary nodule on chest X-ray. These lesions nearly regressed after systemic chemotherapy of VP-16 and discontinuance of Imuran. The second case was a 48-year-old Korean man who had received cyclosporine and prednisone, and Kaposi's sarcoma developed 6 months after renal transplantation with scalp nodule and skin nodules on right axilla and left thigh. He is observed only after discontinuance of Imuran