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장기간 메티마졸 사용 후 발생한 무과립구증과 연조직농양 1예
박세윤,전성완,김여주,김상진 대한갑상선학회 2011 International Journal of Thyroidology Vol.4 No.1
Antithyroid drugs (ATD) has been widely used to treat Graves’ disease. However agranulocytosis, a serious fatal complication of ATD treatment, occurs in about 0.5 percent. The symptoms may mimic viral infections (fever,sore throat), and the potentially life-threatening pyogenic infections can go unrecognized initially. The median duration of drug exposure before the onset of acute agranulocytosis is within 30 days in most cases. We report a case of agranulocytosis with secondary soft tissue infection and abscess occuring after increasing the dose of methimazole in a woman who had taken methimazole for more than 10 years. We administered broad-spectrum antibiotics and aspirated the soft tissue abscess. A review of the medical literature regarding agranulocytosis in the setting of ATDs is presented.
건강한 성인에서 발생한 거대세포바이러스 전염단핵구증과 동반된 위궤양
박세윤,이은정,이태희,구소미,김진녕,전민혁,추은주,김태형 대한소화기내시경학회 2011 Clinical Endoscopy Vol.42 No.6
Cytomegalovirus (CMV) is a prevalent pathogen, with 98∼100% of Korean adults showing prior exposure by serology. A primary infection, such as CMV infectious mononucleosis, is very rare. CMV infectious mononucleosis often presents an initial diagnostic problem. Patients are often hospitalized with a wide variety of clinical diagnoses including fever of unknown origin without pharyngitis and lymphadenopathy. CMV gastrointestinal infections are rare in previously immunocompetent individuals. The most common sites involved are the colon and rectum,although lesions of the stomach have also been described. It is unusual to see CMV infectious mononucleosis and CMV gastrointestinal infection in the same patient. Our patient received symptomatic treatment and fully recovered. We present a case of CMV infectious mononucleosis with gastric ulcers in a previously healthy adult.