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한국인 간질환 (肝疾患) 환자의 B 형 간염 (肝炎) 바이러스 표식자 (標識子) 양성율에 (陽성율) 관한 연구
강진경(Jin Kyung Kang),최흥재(Heung Jae Choi),박인서(In Suh Park),문영명(Young Myoung Moon),이상인(Sang In Lee),김영수(Young Soo Kim),박규숙(Kye Sook Park) 대한소화기학회 1983 대한소화기학회지 Vol.15 No.2
N/A Authors carried out studies to determine the frequency of Hepatitis B virus markers in the serum of 3450 patients with liver diseases, who were diagnosed by clinically, biochemically, serologically and morphologically from September 1977 to August 1982 at Severance hospital, Yonsei University Medical College. The hepatitis B virus markers were measured by method of solid phase radioimmunoassay technique. The results obtained were summarized as follows. The positivity of HBsAg was 78. 9, in chronic active hepatitis, 68.4% in hepatoma, 60.1% in liver cirrhosis, 55.8% in chronic persistent hepatitis, 47.9% In chronic hepatitis, 45.7% in acute viral hepatitis, 37.9% in fulminant hepatitis. The overall positivity of patients with liver diseases was 54.6%. 2) The positivity of anti-HBs was 46.2% in fulminant hepatitis, 33.6% in chronic hepatitis, 27.0% in liver cirrhosis, 21.3% in hepatoma, 20.0% in chronic persistent hepatitis, 18.3% in acute viral hepatitis, 16.3% in chronic active hepatitis. 3) The positivity of anti-HBc was 100.0% in fulminant and chronic persistent hepatitis, 97.8% in chronic active hepatitis, 97. 6% in hepatoma, 88. 2%. In liver cirrhosis, 87% in chronic hepatitis, 74. 6% in acute viral hepatitis. 4) The positivity of HBeAg was 61.1% in chronic active hepatitis, 50.0% in fulminant hepatitis, 44. 6% in acute viral hepatitis, 38. 1% in chronic hepatitis, 37. 5% in chronic persistent hepatitis, 36.0% in liver cirrhosis, 20.2% in hepatoma. 5) The positivity of anti-Hbe was 66. 7% in fulminant hepatitis, 60. 0% in hepatoma, 48.0% in liver cirrhosis, 35.1% chronic active hepatitis, 33.3% in chronic persistent hepatitis, 29.4% in chronic hepatitis, 20.3% in acute viral hepatitis. 6) The detection rate of one or more markers among HBsAg, anti-HBs, anti-HBc in patients with liver diseases was 84.1%. And the most frequent distribution pattern of 5 hepatitis B viral markers was HBsAg(+), anti-HBc(+), anti-HBs( ), HBeAg(+), anti-HBe( ) in acute and chronic hepatitis, HBsAg(+), anti-HBc(+), anti-HBs( ), HBeAg( ), anti-HBe (+) in liver cirrhosis and hepatoma.
한국인의 B 형 간염 (肝炎) 바이러스 표식자 (標識子) 양성율에 (陽性率) 관한 연구
이상인 ( Sang In Lee ),김영수 ( Young Soo Kim ),강진경 ( Jin Kyung Kang ),박인서 ( In Suh Park ),문영명 ( Young Myoung Moon ),최흥재 ( Heung Jai Choi ),박규숙 ( Kye Sook Park ) 대한소화기학회 1983 대한소화기학회지 Vol.15 No.2
N/A This study was to determine the frequency of Hepatitis B virus markers by employing rad- ioimmunoassay technique in 2634 Korean without liver diseases from September 1977 to August 1982 at Severance Hospital, Yonsei University Medical college. The results obtained were summarized as follows. 1) The HBsAg was detected in 324 among 2634 Korean with the positive rate of 12.3% The positive rate of HBsAg was higher in male(13. 6%) than that in female(10. 4%) 2) The positivity of anti-HBs was 40.4%. 3) The detection rate of one or more markers among HBsAg, anti-HBc and anti-HBs was 81. 0%. 4) The positivity of HBeAg was 38.6% and the anti-HBe was detected in 59.1% among asymptomatic HBsAg carrier.