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04 포스터 발표 : 농식품 환경분야(PF) ; PF-02 : 찔레꽃 메탄올 추출물의 프리라디칼소거 활성
강선철 ( Sun Chul Kang ),모니카 ( Monika Bhardwaj ),바후구나 ( Ashutosh Bahuguna ) 한국환경농학회 2015 한국환경농학회 학술대회집 Vol.2015 No.-
Living beings possess an innate antioxidant enzymes defense mechanism to protect the biological molecules from detrimental effects of these reactive oxygen species (ROS). However, during intense oxidative stress, where the pro-oxidants, antioxidant defence system become insufficient to control it, as a reason persist high level of oxidative stress remains, which is responsible for the pathological conditions such as cancer, aging, rheumatoid arthritis, atherosclerosis and neurodegenerative diseases. To balance such an oxidative stress condition an external antioxidant source are required. In view of the above, present study was carried out to investigate the in vitro antioxidant potential of the metahanolic extract of Rosa multiflora flowers. The in vitro antioxidant activity of the different concentration of R.multiflora methanol extract (RMA) was determined by the DPPH● and ABTS●+ radical scavenging method. A significant DPPH● radical scavenging activity was observed in different concentration of RMA as compare to control with the IC50 value of 15.2±0.7 μg/ml. Further more, the antioxidant capacity of RMAwas evaluated by ABTS●+ radical scavenging activity at different concentrations. Finding suggests a significant scavenging activity toward ABTS●+ radicals in a concentration dependent manner, with the IC50 value of 7.42±0.63 μg/ml.